Conservative treatments in gynaecological cancer for fertility preservation
Conservative versus operative treatment for hip fractures in adults
CONsolidated Standards Of Reporting Trials (CONSORT) and the completeness of reporting of randomised controlled trials published in medical journals
Constraint-induced movement therapy for upper limb (arm) recovery after stroke
Constraint-induced movement therapy in the treatment of the upper limb in children with unilateral cerebral palsy
Consultation letters for use by primary care physicians in their care of patients with physical symptoms for which no organic cause can be found
Consultation liaison in primary care appears to improve mental health practice and outcomes for people with a mental disorder
Consumer guidelines for chronic disease management
Consumer involvement in the development of healthcare policy and research, clinical practice guidelines and information for patients
Consumer-delivered training in intimate examination skills for healthcare students and professionals
Consumers and health providers working in partnership for the promotion of person-centred health services: a co-produced qualitative evidence synthesis
Contact tracing methods for tuberculosis
Containment strategies for people with serious mental illness
Contingency management for substance use disorders
Continued lamivudine for adults with lamivudine-resistant chronic hepatitis B virus infection
Continuing education meetings and workshops for health professionals
Continuity of caregivers for care during pregnancy and childbirth
Continuous ambulatory peritoneal dialysis versus automated peritoneal dialysis for end-stage renal disease
Continuous and individual interrupted sutures for repair of episiotomy or second-degree tears
Continuous cardiotocography (CTG) as a form of electronic fetal monitoring (EFM) for fetal assessment during labour
Continuous chest compression versus interrupted chest compression for cardiopulmonary resuscitation (CPR) of non-asphyxial out-of-hospital cardiac arrest (OHCA)
Continuous delivery of a local anaesthetic around the wound to treat pain after bowel surgery through a vertical cut in the abdomen
Continuous distending pressure for respiratory distress in preterm infants
Continuous electronic heart rate monitoring for fetal assessment during labor
Continuous epidural analgesia is superior to intravenous opioid patient-controlled analgesia in relieving postoperative pain for up to 72 hours after abdominal surgery
Continuous glucose monitoring for the prevention of morbidity and mortality in preterm infants
Continuous glucose monitoring systems for the diagnosis of cystic fibrosis-related diabetes
Continuous glucose monitoring systems for type 1 diabetes mellitus
Continuous glucose monitoring systems for type 2 diabetes mellitus
Continuous heparin infusion to prevent thrombosis and catheter occlusion in neonates with peripherally placed percutaneous central venous catheters
Continuous infusion of loop diuretics are safer and more effective than intermittent administration for people with congestive heart failure
Continuous infusion versus intermittent bolus doses of indomethacin for patent ductus arteriosus closure in symptomatic preterm infants
Continuous infusion versus intermittent flushing to prevent loss of function of peripheral intravenous catheters used for drug administration in newborn infants
Continuous nasogastric milk feeding versus intermittent bolus milk feeding for premature infants less than 1500 grams
Continuous negative extrathoracic pressure or continuous positive airway pressure for children with acute respiratory failure and shortage of oxygen
Continuous or intermittent monitoring of people with acute stroke
Continuous passive motion after knee replacement surgery
Continuous passive motion therapy for preventing venous thromboembolism after total knee replacement (arthroplasty)
Continuous positive airway pressure (CPAP) for acute bronchiolitis in children
Continuous positive airway pressure delivery interfaces for obstructive sleep apnoea in adults
Continuous positive airway pressure for cardiovascular disease associated with sleep apneoa
Continuous positive airway pressure versus theophylline for apnea in preterm infants
Continuous positive airways pressure for relieving signs and symptoms of obstructive sleep apnoea
Continuous quality improvement: effects on professional practice and healthcare outcomes in primary care
Continuous subcutaneous insulin infusion (CSII) versus multiple insulin injections for type 1 diabetes mellitus
Continuous subcutaneous insulin infusion versus multiple daily injections of insulin for pregnant women with diabetes
Continuous support for women during childbirth
Continuous ultrasound to the hand benefits grip strength in people with rheumatoid arthritis (RA)
Continuous venous blood filtration for severe acute pancreatitis
Continuous versus intermittent beta-agonists for acute asthma
Continuous versus intermittent bolus feeding for gastro-oesophageal reflux disease
Continuous versus interrupted stitches for closing the skin after non-childbirth surgery
Continuous versus pulsatile oxytocin administration for the augmentation of labour
Contraception interventions for women seeking abortion
Contraceptive pills and venous thrombosis
Contracting out to improve the use of clinical health services and health outcomes in low- and middle-income countries
Contracts between patients and healthcare practitioners for improving patients' adherence to recommended healthcare activities
Contrast-enhanced ultrasound compared with computed tomography, magnetic resonance imaging, and positron emission tomography for diagnosing liver metastases in people with newly diagnosed colorectal cancer
Contribution types and membership points
Control interventions for preventing spread of vancomycin-resistant enterococci (VRE) in hospitals
Control methods for and
Controlled hypotension versus normotensive resuscitation strategy for people with ruptured abdominal aortic aneurysm
Controlled ovarian stimulation protocols for assisted reproduction: a network meta-analysis
Controlled studies for treatment of dysarthia associated with acquired brain injury in childhood urgently required
Controlling blood glucose in treating diabetic foot ulcers (sores)
Controlling high blood sugar levels with insulin in people who have had an acute ischaemic stroke
Convective radiofrequency water vapor thermal therapy for lower urinary tract symptoms in men with benign prostatic hyperplasia
Conventional surgical hemorrhoidectomy results in fewer recurrences than stapled hemorrhoidopexy.
Conversion of calcineurin inhibitor treatment to target of rapamycin inhibitor treatment versus continuation of calcineurin inhibitor treatment for liver transplant recipients
Cooling for newborns with hypoxic ischaemic encephalopathy
Cooling plus inhaled xenon for newborns with hypoxic-ischaemic encephalopathy
Cooling the body after resuscitation following cardiac arrest
Cooling the brain during surgery to prevent death or severe disability in people with brain aneurysms
Cooling therapy for acute stroke
Cooling therapy for acute stroke
Copper IUDs versus long-acting hormone injections and implants for contraception
Cord traction to deliver the afterbirth
Cordyceps sinensis (a Chinese medicinal herb) for treating chronic kidney disease
Cordyceps sinensis (a traditional Chinese medicine) for kidney transplant recipients
Cordyceps sinensis for hypertension in adults
Coriolus versicolor mushroom in colorectal cancer
Corneal collagen cross-linking for infectious keratitis
Corneal collagen cross-linking for thinning of the transparent front part of the eye ('keratoconus')
Coronary artery bypass grafting surgery versus percutaneous coronary intervention for coronary artery disease
Coronary artery bypass surgery performed with versus without cardiac arrest and cardiopulmonary bypass in patients with ischaemic heart disease
Cortical and deep brain stimulation for functional recovery and reducing complications after stroke
Corticosteroid eye drops used in addition to standard antibiotic therapy in the treatment of bacterial keratitis
Corticosteroid injection for de Quervain's tenosynovitis
Corticosteroid injections for shoulder pain
Corticosteroid injections for tennis elbow
Corticosteroid regimens for treatment of acute and chronic graft versus host disease (GvHD) after allogenic stem cell transplantation
Corticosteroid therapy for children with nephrotic syndrome
Corticosteroid therapy for Duchenne muscular dystrophy
Corticosteroid treatments before early birth for reducing death, lung problems and brain haemorrhage in babies
Corticosteroids as standalone or add-on treatment for sore throat
Corticosteroids for acute ischaemic stroke
Corticosteroids for acute severe asthma in hospitalised patients
Corticosteroids for aneurysmal subarachnoid haemorrhage and primary intracerebral haemorrhage
Corticosteroids for bacterial meningitis
Corticosteroids for Bell's palsy
Corticosteroids for cervical ripening and induction of labour
Corticosteroids for children with septic arthritis
Corticosteroids for chronic inflammatory demyelinating polyradiculoneuropathy
Corticosteroids for Guillain-Barré syndrome
Corticosteroids for HELLP syndrome in pregnancy
Corticosteroids for HELLP syndrome in pregnancy
Corticosteroids for hospitalised children with acute asthma
Corticosteroids for induction of remission in Crohn's disease
Corticosteroids for maintenance of remission in Crohn's disease
Corticosteroids for managing people with tuberculous meningitis
Corticosteroids for myasthenia gravis
Corticosteroids for preventing complications following facial plastic surgery
Corticosteroids for preventing graft-versus-host disease after allogeneic myeloablative stem cell transplantation
Corticosteroids for preventing postherpetic neuralgia
Corticosteroids for preventing relapse following acute exacerbations of asthma
Corticosteroids for preventing respiratory complications in the newborn after caesarean section at term
Corticosteroids for pulmonary sarcoidosis
Corticosteroids for the management of cancer pain in adults
Corticosteroids for the management of cancer-related breathlessness in adults with cancer
Corticosteroids for the management of nausea and vomiting not related to chemotherapy, radiotherapy, or surgery in adult cancer patients
Corticosteroids for the prevention and treatment of bronchopulmonary dysplasia: an overview of systematic reviews
Corticosteroids for the resolution of malignant bowel obstruction in advanced gynaecological and gastrointestinal cancer
Corticosteroids for the treatment of idiopathic acute vestibular dysfunction (vestibular neuritis)
Corticosteroids for the treatment of parasitic eosinophilic meningitis
Corticosteroids for toxoplasma infection in the eye
Corticosteroids for treating cerebral malaria
Corticosteroids for treating dengue infection in children and adults
Corticosteroids for treating hypotension in preterm infants
Corticosteroids for treating nerve damage in leprosy
Corticosteroids for treating optic neuritis
Corticosteroids for treating sepsis
Corticosteroids including ACTH (adrenocorticotrophin hormone) for childhood epilepsy other than epileptic spasms
Corticosteroids to treat brain injury
Corticosteroids used in addition to antiviral drugs in patients with Ramsay Hunt syndrome
Corticosteroids versus placebo and NSAIDs for rheumatoid arthritis
Cot-nursing versus incubator care for preterm infants
Cough augmentation techniques for people with chronic neuromuscular disorders
Counselling and education interventions for promoting adherence to treatment for tuberculosis
Counselling for mental health and psychosocial problems in primary care
Couple and family therapies for post-traumatic stress disorder (PTSD)
Couple therapy for depression
Couple-based interventions for improving dyadic adjustment in people with cancer and their spousal partners
Covering ileo- or colostomy in anterior resection for rectal carcinoma is associated with less anastomotic leakage, but does not offer advantage in term of 30 days or long term mortality.
Covidence continues improvements to streamline Cochrane Reviews
Cox-2 Inhibitors in the Prevention of Melanoma
Cranberries for preventing urinary tract infections
Cranberries for treating asymptomatic bacteriuria during pregnancy
Creams, lotions and gels (topical treatments) for fungal infections of the skin and nails of the foot
Creatine for amyotrophic lateral sclerosis/motor neuron disease
Creatine for Parkinson's disease
Creatine for treating muscle disorders
Creatine for women in pregnancy for neuroprotection of the fetus
Crisis intervention for people with severe mental illnesses
Crisis interventions for people with borderline personality disorder
Critical incident audit and feedback to improve perinatal and maternal mortality and morbidity
Cromolyn sodium for the prevention of chronic lung disease in preterm infants
Cryoablation versus radiofrequency catheter ablation for AV nodal re-entrant tachycardia
Cryoplasty for peripheral vascular disease
Cryotherapy for acute non-specific neck pain
Cryotherapy for liver metastases
Cuffed versus uncuffed tubes in children aged eight years and under, having general anaesthetic
Cultural competence education for health professionals
Culturally appropriate health education for people in ethnic minority groups with type 2 diabetes mellitus
Culture media for human pre-implantation embryos for in assisted reproductive technology cycles 
Culture-specific programs for children and adults from minority groups who have asthma
Cultured epithelial autograft in the treatment of acute burn wounds
Cup feeding versus other forms of supplemental enteral feeding for newborn infants unable to fully breastfeed
Curative surgery for obstruction from primary left colorectal carcinoma: Primary or staged resection?
Curcumin for maintenance of remission in ulcerative colitis
Curettage versus other methods of adenoidectomy in children
Currently available malaria vaccines are not yet sufficiently effective, but new vaccines show promise in early tests.
Currently not enough evidence that using cisplatin, a chemotherapy (anti-cancer) drug, before other treatments improves the survival of people with advanced bladder cancer
Currently there is no clear evidence that cholesterol drugs reduce melanoma risk.
Currently there is no evidence available from randomised control trials to determine whether Single Incision Laparoscopic Surgery provides any better effect than Conventional Multi-incision Laparoscopic Surgery for appendicectomy.
Currently there is no evidence to support the routine use of corticosteroids alone in the management of idiopathic pulmonary fibrosis.
Currently there is not enough evidence to conclude that psychosocial treatments alone are adequate to treat people with opiate abuse and dependence.
Custom-made foot orthoses for the treatment of foot pain 
Customised versus population-based growth charts as a screening tool for detecting small for gestational age infants in low-risk pregnant women
Cutaneous antisepsis for prevention of intravascular catheter–associated infection in newborn infants
Cutting back on sugar-sweetened beverages: What works?
Cutting down or changing the fat we eat may reduce our risk of heart disease
Cyanoacrylate microbial sealants for skin preparation prior to surgery
Cycle regimens for frozen-thawed embryo transfer
Cycled light in the intensive care unit for preterm and low birth weight infants
Cyclin-dependent kinase (CDK) inhibitors for hormone receptor-positive advanced breast cancer
Cycling infrastructure (changes to the road environment) for reducing cycling injuries in cyclists
Cyclo-oxygenase (COX) inhibitors for preventing labour before full-term pregnancy
Cyclo-oxygenase (COX) inhibitors for threatened miscarriage
Cyclo-oxygenase (COX) inhibitors for treating preterm labour
Cyclobenzaprine drug treatment for myofascial pain in adults
Cyclofenil is a drug that has been studied in the treatment for Raynaud's phenomenon and associated conditions. It is not used for RP and is an anabolic steroid. See also Cochrane review on Stanazol which is also an anabolic steroid.
Cyclophosphamide compared to ifosfamide for the treatment of sarcoma in children and young adults
Cyclophosphamide for interstitial lung disease associated with connective tissue disease
Cyclophosphamide for treating rheumatoid arthritis
Cyclophosphamide versus methylprednisolone for lupus
Cyclosporin (the drug for preventing organ rejection after transplant) as an oral corticosteroid sparing agent in stable asthma
Cyclosporin A was without significant effects on mortality, liver transplantation, or progression of primary biliary cirrhosis, and patients given cyclosporin A experienced more adverse events
Cyclosporine A eye drops for the treatment of dry eye
Cyclosporine A for induction of remission in severe ulcerative colitis
Cyclosporine for maintenance of remission in Crohn's disease
Cyclosporine for treating rheumatoid arthritis
Cyclosporine for treatment of active Crohn's disease
Cyproterone acetate appears to be as effective as other medications for hirsutism in women caused by excessive androgen production by the ovaries
Cysteine, cystine or N-acetylcysteine supplementation in parenterally fed neonates
Cytoreductive surgery alone or combined with hyperthermic intraperitoneal chemotherapy (HIPEC) for pseudomyxoma peritonei
Cytoreductive surgery and hyperthermic intraperitoneal chemotherapy (HIPEC) for peritoneal carcinomatosis in patients with colorectal cancer
Czech Republic to host Global Evidence Summit 2021
D-cycloserine for autism spectrum disorder
D-dimer for excluding pulmonary embolism in hospital outpatient and accident and emergency populations
D-Dimer tests for the diagnosis of deep venous thrombosis in symptomatic hospital outpatients with a clinical prediction rule
D-penicillamine did not reduce the risk of mortality of patients with primary biliary cirrhosis but increased the occurrences of adverse events
D-Penicillamine for preventing retinopathy of prematurity in preterm infants
Daclizumab, an antibody, as possible alternative therapy to interferon beta in people with relapsing remitting multiple sclerosis
Daily intake of 1 gr dietary calcium may have moderate protective effect on development of colorectal adenomatous polyps
Daily iron supplementation for prevention or treatment of iron deficiency anaemia in infants, children, and adolescents
Dan Shen agents for acute ischaemic stroke
Danazol for pelvic pain associated with endometriosis
Danazol for treating subfertility
Danazol for treatment of women with symptoms caused by uterine fibroids
Danazol is an effective treatment for the reduction of heavy menstrual bleeding, but the adverse effects may be unacceptable to women
Dance therapy for schizophrenia
Dance/movement therapy for cancer patients
Danshen (Chinese medicinal herb) preparations for acute myocardial infarction
Dapagliflozin for type 2 diabetes mellitus
Dapsone as an oral corticosteroid sparing agent for asthma
Darbepoetin alfa to treat anaemia in people with chronic kidney disease
Day 5 versus day 3 embryo biopsy for preimplantation genetic testing for monogenic/single gene defects
Day care for pre-school children
Day centres for severe mental illness
Day hospital versus admission for acute psychiatric disorders
Day hospital versus outpatient care for people with schizophrenia
Day three versus day two embryo transfer following in vitro fertilisation or intracytoplasmic sperm injection
Day-surgery versus overnight stay surgery for laparoscopic cholecystectomy
De-escalation techniques for psychosis-induced aggression or agitation
Deadline extended for expressions of interest to host Global Evidence Summit, 2021
Death audits and reviews for reducing maternal, perinatal and child mortality
Debridement for surgical wounds
Debridement for venous leg ulcers
Debridement of the nasal and sinus cavities in the postoperative care of patients who have had endoscopic sinus surgery for rhinosinusitis
Debriefing interventions for the prevention of psychological trauma in women following childbirth
Debulking hysterectomy followed by chemoradiotherapy versus chemoradiotherapy for FIGO stage IB2/II cervical cancer
Decentralised versus centralised governance of health services
Decision aids for people deciding about taking part in clinical trials
Decision aids for the management of menopausal symptoms
Decision aids to help people who are facing health treatment or screening decisions
Decision coaching for people making healthcare decisions
Decision-support tools via mobile devices to improve quality of care in primary healthcare settings
Decompressive surgery for treating nerve damage in leprosy
Decongestants, antihistamines and nasal irrigation for acute sinusitis in children
Decontamination of environmental surfaces in hospitals to reduce hospital acquired infections