Combination therapy of inhaled steroids and long-acting beta2-agonists compared to inhaled steroids alone for people with COPD
Combinations of anti-cancer drugs to treat high-risk cancers arising from the placenta, known as high-risk gestational trophoblastic neoplasia (GTN)
Combinations of drugs versus single drugs to treat fibromyalgia pain in adults
Combinations of insulin and oral glucose-lowering drugs for people with type 2 diabetes on insulin treatment
Combinations of tocolytic drugs for inhibiting preterm labour
Combinations of topical fluoride (toothpastes, mouthrinses, gels, varnishes) versus single topical fluoride for preventing dental caries in children and adolescents
Combined beta-agonists and anticholinergics compared to beta-agonists alone for adults with asthma treated in emergency departments
Combined calcium, magnesium and potassium supplementation for the management of primary hypertension in adults
Combined chiropractic interventions for low-back pain
Combined conservative interventions for urge, stress or mixed incontinence in adults
Combined corticosteroid and long-acting beta-agonist in one inhaler for chronic asthma
Combined diet and exercise in pregnancy for preventing gestational diabetes mellitus
Combined DTP-HBV vaccine versus separately administered DTP and HBV vaccines for primary prevention of diphtheria, tetanus, pertussis, and hepatitis B
Combined DTP-HBV-HIB vaccine versus separately administered DTP-HBV and HIB vaccines in healthy infants up to two years old
Combined glaucoma and cataract surgery versus cataract surgery alone for eyes with cataract and glaucoma
Combined hormonal contraceptives for heavy menstrual bleeding
Combined hormonal contraceptives taken in extended regimens for more than 28 days compare favorably to traditional 28-day cyclic hormonal contraceptives.
Combined ICS-LABA for children and adults with bronchiectasis
Combined inhaled anticholinergics and beta2-agonists for initial treatment of acute asthma in children
Combined inhalers compared to tiotropium inhalers for the treatment of chronic obstructive pulmonary disease
Combined inhalers versus placebo for the treatment of chronic obstructive pulmonary disease (COPD)
Combined intermittent pneumatic leg compression and medication for the prevention of deep vein thrombosis and pulmonary embolism
Combined large neutral amino acid supplementation for phenylketonuria (PKU)
Combined oral contraceptive pill (OCP) as treatment for primary dysmenorrhoea
Combined pharmacotherapy and psychological therapies for post traumatic stress disorder (PTSD)
Combined psychosocial and agonist maintenance interventions for treatment of opioid dependence
Combined spinal-epidural versus epidural analgesia in labour
Combined spinal-epidural versus spinal anaesthesia for caesarean section
Combined strategies to avoid foot ulcers in patients with diabetes
Combined therapy with statins and fibrates for people with dyslipidaemia
Combined treatment with GnRH analogues and add-back therapy for women with uterine fibroids
Combined use of hyperthermia and radiation therapy for treating locally advanced cervix carcinoma
Combined use of oestrogen and progesterone for preventing miscarriage
Combining antipsychotic medication for the treatment of schizophrenia
Combining two or more drugs vs one drug for pain control in inflammatory arthritis
Comic highlights Cochrane and World Health Organization collaboration for positive birth experience guideline
Commercial hospital discharge packs for breastfeeding women
Commercial versus home-made spacers in delivering bronchodilator therapy for acute therapy in children
Commercial weight loss products and services for obese and overweight adults
Common antiepileptic drugs in pregnancy in women with epilepsy
Common Mental Disorders partnership with the Mental Health Foundation
Communicating to pregnant woman and parents through their mobile devices to improve maternal, neonatal, and child health
Communicating to young people and adults through their mobile devices to improve sexual and reproductive health
Communication skills interventions for medical students
Communication skills training for mental health professionals working with people with severe mental illness
Communication training for parents of preschool children with motor disorders
Community and home-based exercise for the prevention and treatment of hypertension
Community animal health services for improving household wealth and health status of low-income farmers
Community based interventions for reducing dengue incidence
Community coalition-driven interventions to improve health status and reduce disparities in racial and ethnic minority populations
Community first responders for out-of-hospital cardiac arrest in adults and children
Community level interventions to improve food security in developed countries
Community mental health teams (CMHTs) for people with severe mental health problems
Community mobilization and empowerment interventions for preventing HIV in low and middle income countries
Community mobilization for safe motherhood
Community screening for visual impairment in older people
Community views on active case finding for tuberculosis in low- and middle-income countries: a qualitative evidence synthesis
Community wide interventions for increasing physical activity
Community-based exercise and physical activity programmes led by exercise professionals for osteoarthritis
Community-based intervention packages for preventing maternal and newborn illness and death so that newborn outcomes are improved
Community-based interventions for enhancing access to or consumption of fruit and vegetables (or both) among five to 18-year olds
Community-based interventions for improving mental health in refugee children and adolescents in high-income countries
Community-based maternal and newborn educational care packages for improving neonatal health and survival in low- and middle-income countries
Community-based population-level interventions for promoting child oral health
Community-based rehabilitation for people with physical and mental disabilities in low- and middle-income countries
Community-based self-management programs for improving participation in life activities in older adults with chronic conditions
Community-based versus health facility-based management of acute malnutrition for reducing the prevalence of severe acute malnutrition in children 6 to 59 months of age in low- and middle-income countries
Comparative effectiveness of interventions for treating the psychological consequences of sexual abuse in children and adolescents
Comparative efficacy and acceptability of pharmacological treatments for insomnia in adults: a systematic review and network meta-analysis
Comparative efficacy and risk-benefit balance of modulator and suppressant drugs of the immune system in people with multiple sclerosis (MS)
Compared to single chamber ventricular pacemakers, dual chamber pacemakers may reduce the incidence of complications in people with sick sinus syndrome and atrioventricular block
Compared with interferon alone, the addition of ribavirin increases the number of patients with chronic hepatitis C who clear the hepatitis C virus from the blood
Comparing BIS monitoring with clinical assessment for determining the level of sedation of mechanically ventilated adults in intensive care units
Comparing carboplatin-based chemotherapy with cisplatin-based chemotherapy in the treatment of people with advanced lung cancer
Comparing different durations of the same antibiotic therapy for non-severe community-acquired pneumonia in children under five years of age
Comparing different injection frequencies for neovascular age-related macular degeneration
Comparing different surgical techniques used to remove wisdom teeth from the lower jaw
Comparing different types of antibiotics given routinely to women at caesarean section to reduce infections
Comparing different types of chemotherapy for treatment of older people with advanced lung cancer
Comparing different types of scan (CT, MRI, bone scan) for diagnosis of clinically suspected scaphoid fractures, when initial radiographs are negative
Comparing effect estimates of randomized controlled trials and observational studies
Comparing effectiveness of an older antipsychotic (oral fluphenazine) with newer antipsychotics for treating schizophrenia
Comparing electronic monitoring of the baby's heartbeat on a woman's admission in labour using cardiotocography (CTG) with intermittent monitoring
Comparing inhaled corticosteroids with long-acting beta2-agonists in treating chronic obstructive pulmonary disease (COPD)
Comparing initial antiretroviral regimens stavudine or zidovudine as part of three-drug combinations for treatment of HIV infection
Comparing initial antiretroviral regimens tenofovir or zidovudine as part of three-drug combinations for treatment of HIV infection
Comparing reducing smoking to quit with abrupt quitting.
Comparing sedation versus general anaesthesia for children who need to have dental treatment
Comparing single doses of oral analgesics for acute pain in adults after operation
Comparing standard and extended lymph node removal in people with cancer of the head of the pancreas and the periampullary region
Comparing supplemental oxygen with room air for low-risk pregnant women undergoing an elective caesarean section under regional anaesthesia
Comparing surgical groin hernia repair performed with or without mesh
Comparing the effect of different courses of radiotherapy to the chest for patients with incurable lung cancer
Comparing the effect of medications for treating Ascaris infection
Comparing the time taken to give paclitaxel (an anticancer drug) in advanced adenocarcinoma
Comparing treatment of non-severe pneumonia, in children aged 2 to 59 months, with and without antibiotics
Comparing two different techniques of removing cataracts
Comparing two different techniques of removing cataracts
Comparing two types of blood-thinning drugs, factor Xa inhibitors and vitamin K antagonists, to prevent blood clots in people with atrial fibrillation
Comparing walk-in clinics to physician offices and emergency rooms
Comparision of key hole surgery and conventional surgery in the management of small bowel Crohn's disease.
Comparision of two techniques for the placement of a feeding tube to the stomach through the skin in an individual who has difficulty swallowing food
Comparison of a eutectic mixture of local anaesthetics (EMLA) in a cream and amethocaine for relieving the pain children experience when they have injections
Comparison of a light-emitting diode with conventional light sources for providing phototherapy to jaundiced newborn infants
Comparison of an upper limb nerve block using local anaesthetic with opioid analgesia for pain relief following major shoulder surgery
Comparison of animal-derived surfactants for the prevention and treatment of respiratory distress syndrome in preterm infants
Comparison of artificial lenses placed in eyes with uveitis during cataract surgery
Comparison of bowel reconstruction routes after partial surgical removal of the pancreas and duodenum (first part of the small intestine)
Comparison of central adjudication of outcomes and onsite outcome assessment on treatment effect estimates
Comparison of different human papillomavirus (HPV) vaccines and the number of doses administered to prevent HPV-related disease in females and males
Comparison of different platelet transfusion thresholds prior to insertion of central lines in people with a low platelet count
Comparison of different positions that a mother is placed in during caesarean section to improve outcomes for both the mother and her newborn
Comparison of different protein concentrations of human milk fortifier for promoting growth and neurological development in preterm infants
Comparison of different techniques for planned opening of the trachea
Comparison of different types of artificial hip joints that may be used for treating fractures of the hip
Comparison of exenterative surgery versus medical management for women with recurrent gynaecological malignancies
Comparison of interventions for patients diagnosed with pre-cancerous changes of the anal canal (anal intraepithelial neoplasia)
Comparison of medicinal herbs for chronic hepatitis B virus infection
Comparison of non-surgical treatments for women diagnosed with high-grade VIN (precancerous changes of the vulva related to HPV-infection)
Comparison of open versus minimally-invasive (laparoscopic) pyloromyotomy for hypertrophic pyloric stenosis
Comparison of paravertebral anaesthesia to general anaesthesia for breast cancer surgery
Comparison of propofol (an anaesthetic drug) with other drug options for sedating people undergoing painful procedures in emergency departments
Comparison of protocols and registry entries to published reports for randomised controlled trials
Comparison of protocols and registry entries to published reports for systematic reviews
Comparison of surgical interventions for retinal detachment
Comparison of surgical procedures for women diagnosed with precancerous changes of the vulva (high-grade vulval intraepithelial neoplasia)
Comparison of surgical techniques for the treatment of patients with lumbar stenosis
Comparison of the different ways of giving fluids to patients who cannot drink enough, such as patients with Ebola virus disease
Comparison of the stomach-preserving versus classic 'Whipple' operation for people with cancer of the pancreas or the periampullary region
Comparison of the two international standards of chemotherapy for people with early unfavourable or advanced stage Hodgkin lymphoma
Comparison of two different methods of lens removal in cataract surgery, particularly relevant to lower income settings
Comparison of two forms of local anaesthesia for cataract surgery
Comparison of two methods used in screening for colorectal cancer
Comparison of two muscle relaxants, rocuronium and succinylcholine, to facilitate rapid sequence induction intubation
Comparison of two surgical techniques for the control of eye pressure in people with glaucoma
Comparison of video-assisted and non-video-assisted devices for intubation of children
Comparisons of approaches to pelvic floor muscle training for urinary incontinence in women
Comparisons of methods used in adults to put bone fragments of a fractured wrist back into place
Complement inhibitors for age-related macular degeneration
Complementary and alternative medicine treatments for atopic eczema
Complementary and alternative therapies for pain management in labour
Complementary and alternative therapies for post-caesarean pain
Complementary and alternative therapies for shortening labour
Complementary therapies for acne vulgaris
Complementary therapies for chronic plaque psoriasis
Complementary treatments such as hypnosis, psychotherapy, acupuncture, chiropractic and medicinal herbs for bedwetting in children
Complete versus culprit-only revascularisation in ST elevation heart attack with multi-vessel disease
Complex behavioural and educational interventions for bedwetting (nocturnal enuresis) in children
Compliance therapy for schizophrenia
Complications of trocar types for laparoscopic surgery
Compounds which can break down the structure of mucus for lung disease in cystic fibrosis
Comprehensive care programmes for children with medical complexity
Comprehensive Geriatric Assessment for community-dwelling, high-risk, frail, older people
Comprehensive geriatric assessment for older adults admitted to hospital
Comprehensive paediatric assessments for children in out of home care
Comprehensive physiotherapy for rheumatoid arthritis
Compression bandages and stockings to help the healing of venous leg ulcers
Compression bandages or stockings versus no compression for treating venous leg ulcers
Compression hosiery (stockings) for preventing venous leg ulcers returning
Compression stockings for preventing deep vein thrombosis (DVT) in airline passengers
Compression therapy for prevention of post-thrombotic syndrome
Compression therapy for treating post-thrombotic syndrome of mild to moderate severity
Compulsory community and involuntary outpatient treatment for people with severe mental disorders
Computed tomography angiography or magnetic resonance angiography for detecting blood vessel abnormalities in patients with intracerebral haemorrhage
Computed tomography for the diagnosis of hepatocellular carcinoma in chronic advanced liver disease
Computer assisted knee arthroplasty for osteoarthritis and other non-traumatic diseases
Computer programmes for sexual health promotion
Computer-assisted surgery for knee ligament reconstruction
Computer-assisted versus oral-and-written dietary history taking for diabetes mellitus
Computer-assisted versus oral-and-written family history taking for identifying people with elevated risk of type 2 diabetes mellitus
Computer-assisted versus oral-and-written history taking for the management of cardiovascular disease
Computer-assisted versus oral-and-written history taking for the prevention of cardiovascular disease
Computer-based Cognitive Remediation Therapy plus standard care versus standard care for people with schizophrenia or related disorders
Computer-based programmes ('Interactive Health Communication Applications') for people with chronic disease
Computer-based versus in-person stress management programmes for workers
Computer-controlled delivery versus manual delivery of propofol to produce general anaesthesia or sedation in adult patients
Computerised cognitive training for maintaining cognitive function in cognitively healthy people in late life
Computerised cognitive training for maintaining cognitive function in cognitively healthy people in midlife
Computerised cognitive training for preventing dementia in people with mild cognitive impairment
Computerised decision support systems to promote appropriate use of blood products
Computerized advice on drug dosage to improve prescribing practice
Concentrated salt solution versus other treatments to lower pressure around the brain for people with acute traumatic brain injury
Conclusions about the effects of electronic cigarettes remain the same
Concurrent chemoradiotherapy reduces risk of death at two years compared to sequential chemoradiotherapy or radiotherapy alone in patients with stage III non small cell lung cancer
Concurrent chemoradiotherapy with weekly versus three-weekly cisplatin in locally advanced head and neck squamous cell carcinoma
Concurrent health promotion interventions for preventing cardiovascular disease in low- and middle income countries ("resource-limited settings")
Condylocephalic nails versus extramedullary implants for extracapsular hip fractures
Conflicts of interest and recommendations in clinical guidelines, advisory committee reports, opinion pieces, and narrative reviews
Confusion Assessment Method for the intensive care unit (CAM-ICU) for the diagnosis of delirium in adults in critical care settings
Conjugate vaccines for preventing Haemophilus influenzae type b infections in children under 5 years of age
Conjugated pneumococcal vaccine versus polysaccharide pneumococcal vaccine for prevention of pneumonia and invasive pneumococcal disease in immunocompetent and immunocompromised adults and children
Conscious sedation for dental anxiety
Conservative (non-pharmaceutical and non-surgical) treatments for children who have daytime urinary incontinence
Conservative interventions for managing urinary incontinence after prostate surgery
Conservative interventions for shaft fractures of the forearm bones in children
Conservative interventions for treating Achilles tendon ruptures
Conservative interventions for treating scaphoid fractures in adults
Conservative interventions for urinary incontinence in women: an Overview of Cochrane systematic reviews
Conservative interventions for urinary or faecal incontinence, or both, in adults with multiple sclerosis
Conservative management for men with urinary incontinence after prostate surgery
Conservative management of nocturia in adults
Conservative management of pelvic organ prolapse in women
Conservative management of symptomatic and/or complicated haemorrhoids in pregnancy and the puerperium
Conservative treatment for closed fifth (small finger) metacarpal neck fractures
Conservative treatment for exercise-related groin pain
Conservative treatments for whiplash
Conservative treatments in gynaecological cancer for fertility preservation
Conservative versus operative treatment for hip fractures in adults
CONsolidated Standards Of Reporting Trials (CONSORT) and the completeness of reporting of randomised controlled trials published in medical journals
Constraint-induced movement therapy for upper limb (arm) recovery after stroke
Constraint-induced movement therapy in the treatment of the upper limb in children with unilateral cerebral palsy
Consultation letters for use by primary care physicians in their care of patients with physical symptoms for which no organic cause can be found
Consultation liaison in primary care appears to improve mental health practice and outcomes for people with a mental disorder
Consumer guidelines for chronic disease management
Consumer involvement in the development of healthcare policy and research, clinical practice guidelines and information for patients
Consumer-delivered training in intimate examination skills for healthcare students and professionals
Consumers and health providers working in partnership for the promotion of person-centred health services: a co-produced qualitative evidence synthesis
Contact tracing methods for tuberculosis
Containment strategies for people with serious mental illness
Contingency management for substance use disorders
Continued lamivudine for adults with lamivudine-resistant chronic hepatitis B virus infection
Continuing education meetings and workshops for health professionals
Continuity of caregivers for care during pregnancy and childbirth
Continuous ambulatory peritoneal dialysis versus automated peritoneal dialysis for end-stage renal disease
Continuous and individual interrupted sutures for repair of episiotomy or second-degree tears
Continuous cardiotocography (CTG) as a form of electronic fetal monitoring (EFM) for fetal assessment during labour
Continuous chest compression versus interrupted chest compression for cardiopulmonary resuscitation (CPR) of non-asphyxial out-of-hospital cardiac arrest (OHCA)
Continuous delivery of a local anaesthetic around the wound to treat pain after bowel surgery through a vertical cut in the abdomen
Continuous electronic heart rate monitoring for fetal assessment during labor
Continuous epidural analgesia is superior to intravenous opioid patient-controlled analgesia in relieving postoperative pain for up to 72 hours after abdominal surgery
Continuous glucose monitoring systems for monitoring cystic fibrosis-related diabetes
Continuous glucose monitoring systems for the diagnosis of cystic fibrosis-related diabetes
Continuous glucose monitoring systems for type 1 diabetes mellitus
Continuous glucose monitoring systems for type 2 diabetes mellitus
Continuous heparin infusion to prevent thrombosis and catheter occlusion in neonates with peripherally placed percutaneous central venous catheters
Continuous infusion of loop diuretics are safer and more effective than intermittent administration for people with congestive heart failure
Continuous infusion versus intermittent bolus doses of indomethacin for patent ductus arteriosus closure in symptomatic preterm infants
Continuous infusion versus intermittent flushing to prevent loss of function of peripheral intravenous catheters used for drug administration in newborn infants
Continuous nasogastric milk feeding versus intermittent bolus milk feeding for premature infants less than 1500 grams
Continuous negative extrathoracic pressure or continuous positive airway pressure for children with acute respiratory failure and shortage of oxygen
Continuous or intermittent monitoring of people with acute stroke
Continuous passive motion after knee replacement surgery
Continuous passive motion therapy for preventing venous thromboembolism after total knee replacement (arthroplasty)
Continuous positive airway pressure (CPAP) for acute bronchiolitis in children
Continuous positive airway pressure (CPAP) for apnoea of prematurity
Continuous positive airway pressure delivery interfaces for obstructive sleep apnoea in adults
Continuous positive airway pressure for cardiovascular disease associated with sleep apneoa
Continuous positive airway pressure versus theophylline for apnea in preterm infants
Continuous positive airways pressure for relieving signs and symptoms of obstructive sleep apnoea
Continuous positive airways pressure for respiratory distress in preterm infants