Bupropion versus other antidepressive agents for depression
Buteyko breathing for asthma
Bypass for primary percutaneous intervention or thrombolysis at the nearest hospital for patients suffering ST-elevation myocardial infarction
Bypass surgery for chronic lower limb ischaemia
C-reactive protein for diagnosing late-onset infection in newborn infants
Cabergoline for levodopa-induced complications in Parkinson's disease
Cabergoline versus bromocriptine for levodopa-induced complications in Parkinson's disease
CAD/CAM versus traditional indirect methods in the fabrication of inlays, onlays, and crowns
Caesarean delivery for the second twin
Caesarean section for non-medical reasons at term
Caesarean section versus vaginal delivery for preterm birth for women with a single baby (not multiple birth)
Caesarean section versus vaginal delivery for preventing mother to infant hepatitis C virus transmission
Caffeine as an analgesic adjuvant for acute pain in adults
Caffeine for cognition
Caffeine for preventing injuries and errors in shift workers
Caffeine versus theophylline for apnea in preterm infants
Calcimimetics for secondary hyperparathyroidism in chronic kidney disease patients
Calcineurin inhibitor minimisation, ie, reduction or withdrawal, versus continuation of calcineurin inhibitor treatment for liver transplant patients
Calcineurin inhibitor withdrawal or tapering for kidney transplant recipients
Calcitonin for preventing and treating corticosteroid-induced osteoporosis
Calcitonin testing for detection of medullary thyroid cancer in patients with thyroid nodules
Calcitonin used to treat metastatic bone pain
Calcium and vitamin D for treating osteoporosis caused by the use of steroids
Calcium antagonists as an add-on therapy for drug-resistant epilepsy
Calcium antagonists for acute ischemic stroke
Calcium antagonists for aneurysmal subarachnoid haemorrhage
Calcium antagonists for unstable angina
Calcium channel blockers as medical expulsive therapy for ureteric stones
Calcium channel blockers can reduce the death of tubular cells in the kidney after a transplant operation
Calcium channel blockers for antipsychotic-induced tardive dyskinesia
Calcium channel blockers for inhibiting preterm labour and birth
Calcium channel blockers for people with chronic kidney disease requiring dialysis
Calcium channel blockers for potential impaired fetal growth
Calcium channel blockers for preventing heart dysfunction related with iron overload in transfusion-dependent beta thalassaemia
Calcium channel blockers for primary Raynaud's phenomenon
Calcium channel blockers for pulmonary arterial hypertension
Calcium channel blockers for treatment of patients with Raynaud’s phenomenon
Calcium channel blockers versus other classes of drugs for hypertension
Calcium channel blocking drugs for Duchenne muscular dystrophy
Calcium for improving bone mineral density in children
Calcium supplementation during pregnancy for preventing hypertensive disorders and related problems
Calcium supplementation for the management of primary hypertension in adults
Calcium supplementation for weight reduction in overweight or obese people
Calcium, vitamin D or recombinant parathyroid hormone for managing post-thyroidectomy hypoparathyroidism
Call for nominations: Cochrane seeks two external members to join Board
Calling all Citizen Scientists! Join the CitSciMed Blitz!
Calorie-controlled diets for chronic asthma
Campaigning for Evidence: Sara Yaron - a patient's story
Campaigns to encourage children to wear cycle helmets
Campbell Collaboration
Can additional chemotherapy after initial treatment for locally advanced stage cervical cancer reduce recurrence and extend life?
Can antibody induction therapy help to reduce organ rejection for lung transplant recipients?
Can apps be used for the delivery of survey questionnaires in public health and clinical research?
Can brief interventions delivered in schools reduce substance use among adolescents?
Can cannabinoid type 1 receptor antagonists help smokers to quit, and could they also reduce the amount of weight gained during the quitting process?
Can changing antipsychotic medication improve side effects like increases in weight, blood sugar and cholesterol?
Can cognitive stimulation benefit people with dementia?
Can community interventions deter young people from starting to smoke?
Can community interventions reduce smoking among adults
Can cytokines and growth factors help prevent mouth soreness and ulcers (oral mucositis) in patients being treated for cancer?
Can electronic cigarettes help people stop smoking, and are they safe to use for this purpose?
Can exercise give better results after spinal surgery for spinal stenosis?
Can exercise interventions enhance health-related quality of life among cancer survivors?
Can exercise interventions enhance health-related quality of life among people with cancer undergoing active treatment?
Can exercise, for women with gestational diabetes, improve outcomes for mother and her baby?
Can exercising before vaccination reduce numbers of adults who get flu or develop complications?
Can exhaled nitric oxide be used to adjust asthma medications in children with asthma?
Can health care providers who are not doctors perform abortions as well as doctors?
Can illegal cigarette sales to underage youth be prevented, and does it change their smoking behaviour
Can incentives help smokers to quit in the medium to long term?
Can inserting a cervical stitch prevent early births of single babies?
Can Internet-based interventions help people to stop smoking? 
Can interventions delivered by dental professionals help tobacco users to quit?
Can interventions for parents and people caring for children reduce children's exposure to tobacco smoke?
Can interventions to improve professional adherence to guidelines prevent device-related infections?
Can keeping the mouth cold during cancer treatment help to prevent mouth soreness and ulcers in children and adults?
Can lobeline help people to quit smoking
Can mass media campaigns (television, radio, newspapers, billboards and booklets) deter young people from starting to smoke?
Can mefloquine prevent malaria during travel to areas where the disease is widespread?
Can music interventions benefit cancer patients?
Can music interventions replace sedatives for reduction of preoperative anxiety?
Can nicotine receptor partial agonists, including cytisine and varenicline, help people to stop smoking?
Can nicotine replacement therapy (NRT) help people quit smoking?
Can nicotine vaccines help people stop smoking or help stop recent quitters from relapsing?
Can oral Astragalus (Huang qi) prevent frequent acute respiratory tract infections in children?
Can organisational infrastructures be effective in promoting evidence-based nursing practice?
Can people be helped to stop smoking before they have surgery?
Can percussion, diuresis, and inversion therapy improve outcomes for people with lower pole kidney stones following shock wave lithotripsy?
Can physical exercise improve blood flow through the veins?
Can pressure ulcers be prevented by using different support surfaces?
Can programmes delivered by mobile phones help people to stop smoking?
Can programmes delivered in school prevent young people from starting to smoke?
Can psychological therapies help people who self-harm?
Can recruitment strategies make smokers more likely to enter programmes to help them quit smoking?
Can shared decision-making between the patient and the healthcare professional help people with asthma?
Can smartphone apps improve access to asthma self management?
Can smokers be helped to reduce the harm caused by cigarette smoking by smoking fewer cigarettes or using different tobacco products?
Can smoking cessation interventions among adults with pulmonary tuberculosis improve their tuberculosis treatment outcomes?
Can smoking cessation interventions targeted at Indigenous populations achieve smoking abstinence?
Can smoking prevention interventions targeted at Indigenous youth prevent Indigenous youth from starting to smoke or use other tobacco products?
Can strategies intended to improve how care is organised or delivered to people with overweight or obesity lead to greater weight reduction?
Can taking inhaled corticosteroids when needed for symptoms help people with mild asthma from becoming more unwell?
Can tests used to identify the main groin lymph node/s in women with vulval cancer accurately predict whether the cancer has spread to the groin/s?
Can the glucose-lowering drugs insulin secretagogues prevent or delay type 2 diabetes mellitus and its associated complications in persons at increased risk of this disease?
Can the use of standardised packaging for tobacco products reduce the use of tobacco?
Can third-party inspections of whether healthcare organisations are fulfilling mandatory standards improve healthcare outcomes?
Can tobacco control programmes that include a mass media campaign help to reduce levels of smoking among adults?
Can training health professionals to ask people if they smoke increase offers of advice and help patients quit?
Can ultrasound therapy help to heal venous (varicose) leg ulcers and/or improve symptoms?
Can users of waterpipes be helped to quit through smoking cessation interventions?
Can we increase adherence to medications that help smokers to quit?
Can xylitol used in products like sweets, candy, chewing gum and toothpaste help prevent tooth decay in children and adults?
Canadian C-spine rule and the National Emergency X-Radiography Utilization Study (NEXUS) for detecting clinically important cervical spine injury following blunt trauma
Cancer genetic risk assessment for individuals at risk of familial breast cancer
Cancer patients with fever and suspected infection can be treated with a single 'new-generation' beta-lactam antibiotic
Cannabinoids for epilepsy
Cannabinoids for the treatment of dementia
Cannabinoids for Tourette syndrome
Cannabis for schizophrenia
Cannabis for the treatment of Crohn's disease
Cannabis for the treatment of ulcerative colitis
Cannabis products for adults with chronic neuropathic pain
Cannabis products for people with fibromyalgia
Cannabis-based medicine for nausea and vomiting in people treated with chemotherapy for cancer
Capecitabine for ER-positive versus ER-negative breast cancer
Capsaicin applied to the skin for chronic neuropathic pain in adults
Capsaicin for allergic rhinitis
Capsaicin for non-allergic rhinitis
Capsule endoscopy for the diagnosis of oesophageal varices in people with chronic liver disease or portal vein thrombosis
Carbamazepine and oxcarbazepine for the treatment of behavioural and psychological symptoms of dementia (BPSD)
Carbamazepine does not appear to be effective in reducing cocaine dependence, with high dropout rates and adverse effects
Carbamazepine for chronic neuropathic pain and fibromyalgia in adults
Carbamazepine for schizophrenia
Carbamazepine versus phenytoin (given as a single drug treatment) for epilepsy
Carbamazepine versus valproate monotherapy for epilepsy
Carbetocin for preventing postpartum haemorrhage
Carbohydrate or fat-restricted diets for obesity
Carbohydrate supplementation of human milk to promote growth in preterm infants
Carbon dioxide detection for diagnosis of inadvertent respiratory tract placement of enterogastric tubes in children
Carbon dioxide detection for testing nasogastric tube placement in adults
Carbonic anhydrase inhibitors for hypercapnic ventilatory failure in chronic obstructive pulmonary disease
Cardiac resynchronization therapy for dilated cardiomyopathy
Cardiac testing for coronary artery disease in potential kidney transplant recipients
Cardioselective beta-blockers for reversible airway disease
Cardiotocography (a form of electronic fetal monitoring) for assessing a baby's well-being in the womb during pregnancy
Cardiotocography for antepartum fetal assessment
Cardiovascular safety of phosphodiesterase inhibitors for treating erectile dysfunction in elderly men
Care co-ordination interventions to improve outcomes during pregnancy and early childhood (up to 5 years)
Care delivery and self management strategies for adults with epilepsy
Care delivery and self-management strategies for children with epilepsy
Care for pregnant women who have experienced genital cutting
Care prior to and during subsequent pregnancies following stillbirth for improving outcomes
Care prior to the next pregnancy for women diagnosed with gestational diabetes
Caregiver involvement in interventions for improving children's dietary intake and physical activity behaviors
Caregiver-mediated exercises for improving outcomes after stroke
Cariprazine versus placebo for schizophrenia
Carisbamate add-on therapy for drug-resistant partial epilepsy
Carnitine for fatigue in patients with multiple sclerosis (MS)
Carnitine supplementation for preterm infants with recurrent apnoea
Carnitine supplementation of parenterally fed neonates
Carnitine supplements for treating people with inborn errors of metabolism
Carotid endarterectomy for asymptomatic carotid stenosis
Carotid endarterectomy for carotid stenosis in patients selected for coronary artery bypass graft surgery
Carotid surgery in patients who have symptoms with narrowing of the carotid artery
Carvedilol versus non-selective beta-blockers for portal hypertension in cirrhosis
Case management approaches to home support for people with dementia
Case management for integrated care of frail older people in community settings
Case management for people with severe mental disorders
Case management: effects on professional practice and health care outcomes
Case mangement for persons with substance use disorders.
Castor oil, bath and/or enema for cervical priming and induction of labour
Cataract surgery in people with age-related macular degeneration
Catheter ablation versus pharmacological treatment for patients with Wolff-Parkinson-White syndrome
Catheter ablation would be an alternative to inhibit recurrence of paroxysmal or persistent atrial fibrillation
Catheter balloons and metal tubes for narrowing of neck arteries
Catheter insertion techniques for improving catheter function and clinical outcomes in peritoneal dialysis patients
Catheter lock treatments for catheter-related infections in children with cancer
Catheter policies for management of long-term voiding problems in adults with nerve damage affecting the bladder
Catheter-directed therapies for the treatment of massive and submassive acute pulmonary embolism
Cefepime versus other beta-lactam antibiotics for the treatment of infections in non-neutropenic patients
Celebrating 20 years of Cochrane in Spain
Celebrating the 20th Anniversary of Cochrane Brazil
Celecoxib for RA
Celecoxib for schizophrenia
Celiac plexus block (CPB) in patients with unresectable pancreatic cancer-related pain
Cell salvage (collecting a patient's own blood during surgery) for reducing transfusions with donated blood
Cell-based therapies for amyotrophic lateral sclerosis/motor neuron disease (ALS/MND)
Celsior solution versus University of Wisconsin solution in liver preservation for transplantation
Cemented versus cementless surgical approach for total hip arthroplasty revision
Cemented versus cementless total hip arthroplasty for osteoarthrosis and other non-traumatic diseases
Central action beta-blockers versus placebo for neuroleptic-induced acute akathisia
Central venous access sites to prevent venous blood clots, blood vessel narrowing, and infection
Central venous catheter coating with antiseptics or antibiotics for reducing catheter-related infections in adults
Central venous catheter removal for adults and children suffering from bloodstream infections caused by Candida species
Centralisation of care may prolong survival in women with ovarian cancer, and possibly more generally, gynaecological cancer
Centre-based day care for children younger than five years of age in high-income countries
Centre-based day care for children younger than five years of age in low- and middle-income countries
Centre-based early education interventions for improving school readiness
Cephalic version by moxibustion for breech presentation
Cephalic version by postural management for breech presentation
Cephalocondylic intramedullary nails versus extramedullary implants for extracapsular hip fractures in adults
CERA treatment for anaemia in people with chronic kidney disease
Ceramic inlays for restoring posterior teeth
Cerebral near-infrared spectroscopy (NIRS) for perioperative monitoring of brain oxygenation in children and adults
Cerebral near-infrared spectroscopy monitoring for prevention of brain injury in very preterm infants
Cerebrolysin for acute ischaemic stroke
Cerebrolysin for Alzheimer's disease
Cerebrolysin for vascular dementia
Cerebrospinal fluid drainage for thoracic and thoracic abdominal aortic aneurysm surgery
Cerivastatin for lowering lipids
Cernilton, an extract from rye grass pollen, may help to relieve some urinary symptoms caused by an enlarged prostate gland, but more research is needed.
Certolizumab pegol for induction of remission in Crohn's disease
Certolizumab pegol for treating adults with rheumatoid arthritis
Cervical assessment by ultrasound for preventing preterm delivery
Cervical cap versus diaphragm for birth control
Cervical cerclage in combination with other treatments for preventing preterm birth in singleton pregnancies
Cervical ripening before first trimester surgical evacuation for non-viable pregnancy
Cervical stitch (cerclage) for preventing pregnancy loss in women
Cervical stitch for preventing preterm birth in women with a multiple pregnancy
Cervico-thoracic or lumbar sympathectomy for neuropathic pain
Cessation of medication for people with schizophrenia already stable on chlorpromazine
Cetuximab: a new treatment for advanced non-small cell lung cancer
CFTR correctors, a therapy for cystic fibrosis targeted at specific mutations
Changes at the workplace for preventing disability in workers on sick leave
Changes in out-of-pocket payments on utilisation of health care services
Changing atrial fibrillation to a regular heart rhythm using specific drugs has no advantage over controlling the heart rate in elderly people
Characteristics of randomised trials in ophthalmology using a single eye per person design
Chelation for autism spectrum disorder (ASD)
Chelation therapy for atherosclerotic cardiovascular disease
Chemicals for sticking the outer lung surface to surrounding membranes compared to surgery to stop air persistently collecting in the chest
Chemo-mechanical treatment of tooth decay
Chemo-radiotherapy versus surgery-based treatment for Stage IIIA non-small cell lung cancer: a systematic review and network meta-analysis
Chemoimmunotherapy versus chemotherapy for metastatic malignant melanoma
Chemoprevention agents for prostate cancer
Chemoradiation in locally advanced vulval cancer
Chemoradiotherapy for cervical cancer:  results of a meta-analysis
Chemotherapy (anticancer drugs) for patients with advanced small cell lung cancer
Chemotherapy (drug treatment) for inoperable thymic cancer in adults
Chemotherapy after surgery for early stage non-small cell lung cancer
Chemotherapy after surgery for stage III and IV endometrial cancer
Chemotherapy after surgery versus surgery alone for stomach cancer
Chemotherapy alone versus endocrine therapy alone for metastatic breast cancer
Chemotherapy and radiotherapy may improve survival and quality of life in people with advanced pancreatic cancer
Chemotherapy and supportive care versus supportive care alone for advanced non-small cell lung cancer
Chemotherapy as an adjunct to radiotherapy in locally advanced nasopharyngeal carcinoma
Chemotherapy before surgery for patients with surgically removable cancer of the esophagus
Chemotherapy before surgery in patients with adenocarcinoma of the esophagus, the gastroesophageal junction, and the stomach
Chemotherapy before surgery or radiotherapy or both for women with cervical cancer that has spread beyond the cervix to the tissues close by
Chemotherapy can improve survival rates for non-small cell lung cancer
Chemotherapy delivered via the hepatic artery following surgical resection of liver metastases arising from colorectal cancer does not improve survival.