Biomarkers for diagnosis of acute appendicitis in adults

This is a protocol for a Cochrane Review (diagnostic). The objectives are as follows:

To determine the diagnostic accuracy of biomarkers for detecting acute appendicitis in hospitalised adults with suspected acute appendicitis.

Secondary objectives

To determine (if possible) the diagnostic accuracy of biomarkers for detecting:

  • uncomplicated and complicated (gangrenous or perforated) acute appendicitis;

  • acute appendicitis in males and females;

  • acute appendicitis in women of reproductive age;

  • acute appendicitis in pregnancy;

  • acute appendicitis at different time intervals from onset of pain.

This is a protocol.