To determine the benefits and harms of branched-chain amino acid (BCAA) supplementation administered both enterally and parenterally in neonates. We will make comparisons as follows: parenteral nutrition with and without BCAA supplementation; enteral BCAA supplementation versus no supplementation; and any type of supplementation including enteral, parenteral and both ways versus no supplementation. We will investigate the effectiveness of different levels of supplementation assessed in the trials. There will be two subgroups within each comparison – preterm and term infants.
This is a protocol.