Antivenom for snake venom-induced neuromuscular paralysis
Antiviral agents for hepatitis B virus-related cirrhosis
Antiviral agents for treating CMV infection of the nervous system in people with HIV
Antiviral agents for treatment of herpes simplex virus infection in neonates
Antiviral drugs amantadine and rimantadine for preventing and treating the symptoms of influenza A in adults
Antiviral drugs can prevent cytomegalovirus (CMV) infection and disease after an organ transplant.
Antiviral drugs for sudden hearing loss (without known cause)
Antiviral drugs used as protective and preventive therapy reduce CMV disease and CMV-associated deaths in solid organ transplant recipients
Antiviral medication for the treatment of infectious mononucleosis (glandular fever)
Antiviral medicines, interferon, and corneal surface removal in the treatment of herpes simplex virus infection of the eye
Antiviral prophylaxis for varicella zoster in immunocompromised patients (excluding haematological malignancies)
Antiviral therapy for genital herpes for prevention of HIV transmission
Antiviral therapy for recurrent liver graft infection with hepatitis C virus
Antiviral therapy for symptomatic congenital cytomegalovirus infection in neonates and infants up to 3 months of age
Antiviral therapy to prevent the recurrence of chronic hepatitis C infection in patients undergoing liver transplantation
Antiviral treatment for Bell's palsy
Antiviral treatment for chronic hepatitis C in patients with HIV infection
Antiviral treatment for influenza infection in people with cystic fibrosis
Antiviral treatment for preventing nerve pain after shingles (postherpetic neuralgia)
Antiviral treatments for lamivudine-resistant chronic hepatitis B adult patients
Antivirals for recurrent respiratory papillomatosis
Antivirals may provide limited help for the common cold but they are not a cure and none are licensed
Apomorphine for the treatment of erectile dysfunction
Appetite stimulants for people with cystic fibrosis
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Applying negative pressure rapidly or in steps for vacuum extraction assisted vaginal delivery
Applying positive pressure at the end of each breath during anaesthesia for prevention of mortality and postoperative pulmonary complications
Appointment of a new Editor in Chief for the Cochrane Library
Appointment of lead to independent advisory group
Approaches for helping children and adolescents with cystic fibrosis to take part in decisions about their healthcare
Aptrotinin and tranexamic acid may show promise in decreasing blood loss and blood transfusion requirements
Aquablation for the treatment of lower urinary tract symptoms in men with benign prostatic hyperplasia
Aquatic exercise for people with osteoarthritis in the knee or hip
Aquatic exercise training for fibromyalgia
Aquatic therapy exercise for treating rheumatoid arthritis
Aqueous shunt surgery and mitomycin C
Aqueous shunts for glaucoma
Arbidol for preventing and treating influenza in adults and children
Are angiotensin receptor blockers (ARBs) an effective treatment for heart failure?
Are anti-blood clotting drugs beneficial for people with chronic kidney disease?
Are antibiotics a safe and effective additional treatment for asthma exacerbations?
Are antibiotics beneficial for flare-ups of chronic obstructive pulmonary disease?
Are antibiotics more effective when given continuously or intermittently to people with bronchiectasis?
Are any effective treatment options available for the management of granulosa cell tumour of the ovary?
Are asthma self-management interventions effective when delivered in schools for children, and how should they be delivered?
Are cardioselective beta-blockers a safe and effective treatment in patients with chronic obstructive pulmonary disease?
Are changes to diet effective to manage mineral and bone abnormalities in people with chronic kidney disease?
Are combined aclidinium and long-acting beta2-agonist inhalers effective and safe for people with stable COPD?
Are communication interventions effective for minimally verbal children with autism spectrum disorder?
Are cyclical progestogens an effective and safe treatment for heavy menstrual bleeding compared to other medical treatments?
Are diuretics effective for treating people with nephrotic oedema?
Are inhaled anticholinergics added to β2-agonists beneficial in children hospitalised with acute asthma?
Are inhalers containing umeclidinium bromide effective and safe for people with COPD?
Are interventions that are implemented in alcohol server settings (e.g. bars and pubs) effective for preventing injuries?
Are interventions to improve clinical incidence reporting effective?
Are interventions to keep people sleeping on their side the best way to treat obstructive sleep apnoea?
Are local opinion leaders effective in promoting best practice of healthcare professionals and improving patient outcomes?
Are newer methods for destroying the lining of the uterus (endometrial ablation) more effective and safer compared to established methods?
Are non-absorbable disaccharides associated with beneficial or harmful effects in people with cirrhosis and hepatic encephalopathy?
Are non-steroidal anti-inflammatory drugs safe and effective for treating heavy menstrual bleeding?
Are non-steroidal anti-inflammatory medicines known as leukotriene receptor antagonists helpful and safe for eczema?
Are oral antibiotics as effective as a combination of injected and oral antibiotics for kidney infections in children?
Are oral homeopathic medicinal products effective and safe to prevent and treat acute respiratory tract infections in children?
Are particular types of colloid solution safer for replacing blood fluids than others?
Are physiotherapy or ergonomic workplace adjustments helpful in participants with work-related arm, neck or shoulder complaints?
Are psychological therapies effective in treating depression in patients with COPD?
Are psychological therapies effective in treating depression that did not get better with previous treatment?
Are psychosocial interventions effective for treating depression among people on dialysis?
Are school-based programmes aimed at children who are considered at risk of aggressive behaviour, effective in reducing violence?
Are shorter courses of systemic steroids as effective as conventional longer courses in the treatment of patients with flare-ups of COPD?
Are smoking cessation interventions effective for quitting smoking and reducing disease activity in people with chronic inflammatory joint disease?
Are stage-based interventions more effective than non-stage-based ones in helping smokers to quit?
Are substances that inhibit the growth of new blood vessels (angiogenesis inhibitors), alone or in combination with conventional chemotherapy, likely to improve outcomes for women with ovarian cancer?
Are telephone or internet check-ups a safe alternative to being seen face-to-face?
Are there any differences in survival between people with low-grade glioma having early compared with delayed radiotherapy at the time of progression?
Are there any effective interventions to help individuals with depression to quit smoking?
Are there any effective interventions to help individuals with schizophrenia to quit or to reduce smoking?
Are there any smoking cessation programmes that can help adolescents to stop smoking?
Are there effective medications for treating depression that does not improve with the first medication used?
Are there effective methods to improve the process of referring patients to specialised care?
Are there ways in which workplace bullying can be prevented?
Are tiotropium plus combination inhalers better than tiotropium or combination inhalers alone for the treatment of COPD?
Are topical and device-based treatments effective in people with fungal infections of the toenails?
Area-wide traffic calming (such as introducing road/speed humps) may reduce death and injury from road traffic crashes but more research is needed
Aripiprazole alone or in combination with other drugs for treating the acute mania phase of bipolar disorder
Aripiprazole dose for schizophrenia
Aripiprazole for autism spectrum disorders (ASD)
Aripiprazole for neuroleptic induced hyperprolactinaemia
Aripiprazole for people with schizophrenia whose illness has been partially responsive to clozapine
Aripiprazole for schizophrenia
Aripiprazole versus chlorpromazine for people with schizophrenia and schizophrenia-like psychoses
Aripiprazole versus haloperidol for people with schizophrenia and schizophrenia-like psychoses
Aripiprazole versus other atypical antipsychotics
Aripiprazole versus perphenazine for people with schizophrenia and schizophrenia-like psychoses
Aripiprazole versus placebo for schizophrenia
Aripiprazole versus sulpiride for people with schizophrenia and schizophrenia-like psychoses
Aripiprazole versus typical antipsychotic drugs for schizophrenia
Aripiprazole versus ziprasidone for schizophrenia
Arm basis training and arm ability training: two impairment-oriented exercise training techniques for improving arm function after stroke
Arm exercise training for COPD
Aromatase inhibitors for ovulation induction
Aromatase inhibitors for short stature in male children and adolescents
Aromatase inhibitors for subfertility treatment in women with polycystic ovary syndrome
Aromatase Inhibitors for the adjuvant treatment of breast cancer in postmenopausal women
Aromatase inhibitors for treatment of advanced breast cancer in postmenopausal women
Aromatase inhibitors for women with uterine fibroids
Aromatherapy and massage for symptom relief in people with cancer
Aromatherapy and massage to relieve symptoms in patients with cancer
Aromatherapy for pain management in labour
Aromatherapy for promotion of relaxation and sleep, relief of pain, and reduction of depressive symptoms in dementia
Aromatherapy for treating postoperative nausea and vomiting
Arsenic trioxide for the treatment of acute promyelocytic leukaemia
Art therapy for schizophrenia or schizophrenia-like illnesses
Artemether injection for treating people with severe malaria
Artemether-lumefantrine (four-dose regimen) for treating uncomplicated malaria
Artemether-lumefantrine (six-dose regimen) for treating uncomplicated malaria
Artemether-lumefantrine for treating uncomplicated falciparum malaria
Artemisinin derivatives for treating severe malaria
Artemisinin drugs for treating uncomplicated malaria are better used in combination therapy
Artemisinin-based combination therapy (ACT) for treating non-severe malaria due to Plasmodium vivax
Artemisinin-based combination therapy for uncomplicated malaria in children with HIV
Artemisinin-based combination treatments for uncomplicated malaria
Artemisinin-naphthoquine for treating uncomplicated Plasmodium falciparum malaria
Artesunate plus mefloquine in areas with low malaria transmission performed better than mefloquine alone for uncomplicated P. falciparum malaria
Artesunate reduces death from severe malaria
Arthrocentesis and lavage for treating temporomandibular joint disorders
Arthrographic distension for adhesive capsulitis (frozen shoulder)
Arthroplasties for hip fracture in adults
Arthroplasty versus fusion for single-level cervical degenerative disc disease
Arthroscopic debridement for osteoarthritis of the knee
Arthroscopy for temporomandibular disorders
Artichoke leaf extract for treating high cholesterol levels
Artificial corneal devices versus human donor corneas for people undergoing repeat corneal transplantation
Artificial limb rehabilitation for older people with a leg amputated at or above the knee because of blood circulation problems
Artificial opening of the cervix during a planned caesarean section before the start of labour for reducing postoperative problems
Artificial tube feeding methods for use with patients with head and neck cancer who are receiving treatment with radiotherapy, chemotherapy or both
Artificial, blue-light filtering lenses in the eye for protecting the macula (back of the eye) after cataract surgery
As required versus fixed schedule analgesic administration schedules for treating postoperative pain in children and adults
Asenapine versus other atypical antipsychotics for schizophrenia
Asenapine versus placebo for schizophrenia
Asenapine versus typical antipsychotics for schizophrenia
Asking men to pass a catheter into their own urethra to try to stop a urethral stricture from coming back
Aspiration and sclerotherapy versus hydrocoelectomy for treating hydrocoeles
Aspiration of the elbow joint for treating radial head fractures
Aspirin (single dose) for relief of perineal pain after childbirth
Aspirin and anti-inflammatory drugs for the prevention of dementia
Aspirin and/or heparin for women with unexplained recurrent miscarriage with or without inherited thrombophilia
Aspirin as an add-on treatment to antipsychotics for people schizophrenia
Aspirin as an additional treatment for giant cell arteritis
Aspirin desensitisation therapy for aspirin-intolerant chronic rhinosinusitis
Aspirin dosage for the prevention of graft occlusion in people undergoing coronary surgery
Aspirin for acute episodic tension-type headache in adults
Aspirin for primary prevention of coronary heart disease
Aspirin for women undergoing assisted reproductive technology (ART).
Aspirin or heparin or both for improving pregnancy outcomes in women with persistent antiphospholipid antibodies and recurrent pregnancy loss
Aspirin to prevent stroke in people with an irregular and rapid heart beat (atrial fibrillation) without rheumatic heart disease and a history of stroke or transient ischaemic attacks (TIA)
Aspirin with or without an antiemetic for acute migraine headaches in adults
Aspirin, steroid and non-steroidal anti-inflammatory drugs use for treating Alzheimer's disease
Assertive community treatment for people with severe mental disorders
Assessing the effects of solid versus liquid dosage forms of oral medications on adherence and acceptability in children
Assessment and support during early labour for improving birth outcomes
Assessment of changes in memory and everyday function in older people using a structured questionnaire, the IQCODE
Assessment of techniques to ascertain correct placement of a breathing tube in neonates
Assisted hatching of fertilised eggs to improve the chances of pregnancy in assisted conception (IVF and ICSI)
Assisted reproductive technology: an overview of Cochrane Reviews
Assistive technology (electronic aids) for children and young people with low vision
Assistive technology for memory support in dementia
Assistive technology for rheumatoid arthritis
Assistive technology, including orthotic devices, for the management of contractures in adult stroke patients
Association between personal conflicts of interest and recommendations on medical interventions
Asthma education for school staff
Asthma reliever inhalers (beta2-agonists) used for exercise-induced asthma and exercise-induced bronchoconstriction
Asthma self management education with either regular healthcare professional review or written action plans or both in adults
Astragalus (a traditional Chinese medicine) for treating chronic kidney disease
At this time, benzodiazepines cannot be recommended for the treatment of non-alcohol related delirium
Ataluren and similar compounds (specific therapies for premature termination codon class I mutations) for cystic fibrosis
Atherectomy for peripheral arterial disease
Atomoxetine for Attention Deficit Hyperactivity Disorder (ADHD) in children and adolescents
Atomoxetine for schizophrenia
Atovaquone-proguanil appears to be more effective than individual drugs for treating uncomplicated malaria, but there are few data comparing atovaquone-proguanil to other combination therapies
Atraumatic restorative treatment (hand instruments only) compared with conventional treatment for managing tooth decay
Atrial fibrillation surgery for patients undergoing heart surgery
Atrial natriuretic peptide for preventing and treating acute kidney injury
Atropine therapy versus no atropine therapy for the prevention of adverse events in paediatric patients undergoing intubation
Attachment to the jejunum versus stomach for the reconstruction of pancreatic stump following pancreaticoduodenectomy ('Whipple' operation)
Attachments for implant dentures
Attention-based interventions for the management of pain and distress in young children (3-12 years) with burn injuries
Atypical antipsychotic drugs for disruptive behaviour disorders in children and youths
Atypical antipsychotic medications for adolescents with psychosis
Atypical antipsychotics benefit people with dementia but the risks of adverse events may outweigh the benefits, particularly with long term treatment
Atypical antipsychotics for people with both schizophrenia and depression
Atypical Antipsychotics for Tourette's Syndrome
Audio recordings of consultations with doctors for parents of critically sick babies
Audio recordings or written summaries of key consultations for adults with cancer
Audio-visual presentation of information used in the informed consent process for people considering entering clinical trials
Audit and feedback: effects on professional practice and patient outcomes
Audit filters for improving trauma care
Auditory integration therapy for autism spectrum disorders
Auditory-verbal therapy for promoting spoken language development in children with permanent hearing impairments
Aural toilet (ear cleaning) for chronic suppurative otitis media
Auranofin for the treatment of rheumatoid arthritis
Auricular acupuncture for cocaine dependence
Auricular acupuncture for opiate dependence in substance misuse treatment programmes
Australian guideline developers join forces to advance Living Evidence
Author Interview: Alcoholics Anonymous and other 12-step programs for alcohol use disorder
Autoinflation for hearing loss associated with otitis media with effusion (glue ear)
Autologous blood and platelet rich plasma injection therapy for lateral elbow pain
Autologous blood product injections including platelet-rich plasma for osteoarthritis of the knee
Autologous bone marrow-derived and blood-derived biological therapies (including cellular therapies and platelet-rich plasma) for bone healing in adults
Autologous chondrocyte implantation for full thickness articular cartilage defects of the knee
Autologous fat grafting for breast reconstruction
Autologous platelet concentrates for treating periodontal infrabony defects
Autologous platelet-rich plasma (PRP) for chronic wounds
Autologous platelet-rich plasma for treating surgical wounds
Autologous versus prosthetic arteriovenous fistulae for vascular access
Autolytic debridement for pressure ulcers
Automated monitoring for the early detection of sepsis in patients receiving care in intensive care units
Automated oxygen delivery for preterm infants with respiratory dysfunction
Automated telephone communication systems for preventing disease and managing long-term conditions
Automated training devices for improving walking after stroke
Avatar therapy for schizophrenia or related disorders
Avoidance of bottles during the establishment of breast feeds in preterm infants
Awake language mapping for cerebral glioma surgery
Ayurveda interventions for rheumatoid arthritis
Ayurvedic herbal preparations for hypercholesterolaemia
Ayurvedic medicine for schizophrenia
Ayurvedic treatments for diabetes mellitus:
Azapirones for generalized anxiety disorder (GAD)
Azapirones versus placebo for panic disorder in adults
Azathioprine and 6-mercaptopurine for maintenance of remission in ulcerative colitis
Azathioprine and 6-mercaptopurine for the maintenance of surgically-induced remission in Crohn’s disease
Azathioprine as an oral corticosteroid sparing agent for asthma
Azathioprine for treating rheumatoid arthritis
Azathioprine or 6-mercaptopurine for maintenance of remission in Crohn's disease
Azathioprine or 6-mercaptopurine for the treatment of active Crohn's disease
Azithromycin for acute lower respiratory tract infections
Azithromycin for treating uncomplicated typhoid and paratyphoid fever (enteric fever)
Azithromycin for treatment of bronchiolitis obliterans syndrome in adult lung transplant recipients
Azithromycin is not useful as monotherapy for uncomplicated malaria. In combinations with other antimalarials, it may need to be used at high doses, potentially affecting tolerability.
Azithromycin versus penicillin G benzathine for early syphilis
B-type natriuretic peptide-guided treatment for heart failure patients
Bacille Calmette-Guerin (BCG) vaccine for induction of remission in Crohn's disease
Bacillus Calmette-Guérin or mitomycin C for treatment of non-muscle-invasive bladder cancer
Back School for the treatment of chronic low back pain
Back schools for acute and subacute non-specific low-back pain
Back schools for non-specific low-back pain
Baclofen for alcohol use disorder
Baclofen for alcohol withdrawal syndrome
Balance training (proprioceptive training) for rheumatoid arthritis.