Dopamine agonists for preventing future miscarriage in women with high prolactin levels and a history of recurrent miscarriage
Dopamine agonists for restless legs syndrome
Dopamine agonists for the treatment of people who misuse cocaine
Dopamine agonists for traumatic brain injury
Dopamine agonists to prevent ovarian hyperstimulation syndrome in women undergoing assisted reproduction technology
Dopamine for prevention of morbidity and mortality in term newborn infants with suspected perinatal asphyxia
Dopamine transporter imaging for the diagnosis of dementia with Lewy bodies
Dopamine versus dobutamine for hypotensive preterm infants
Dopamine versus no treatment to prevent renal dysfunction in indomethacin-treated preterm newborn infants
Dopaminergic agents versus control for enhancing stroke recovery and rehabilitation
Dopaminergic antagonists for alcohol dependence
Doppler trans-thoracic echocardiography for detection of pulmonary hypertension in adults
Doppler ultrasound for fetal assessment in high risk pregnancies
Doppler ultrasound of blood vessels in the placenta and uterus of pregnant women as a way of improving outcome for babies and their mothers
Doppler ultrasound of fetal blood vessels in normal pregnancies
Doppler ultrasound of fetal vessels in pregnancies at increased risk of complications
Doppler ultrasound, CT angiography, MR angiography, and contrast-enhanced MR angiography versus intra-arterial angiography for moderate and severe carotid stenosis in symptomatic patients
Dornase alfa, an inhaled drug, for treating lung disease in cystic fibrosis
Dosage intervals of amoxicillin for the treatment of acute middle ear infection
Dose-escalated radiotherapy for clinically localised and locally advanced prostate cancer
Dosing regimens for pancreatic enzyme replacement therapy (PERT) in cystic fibrosis
Double gloving to reduce surgical cross-infection
Double wall versus single wall incubator for reducing heat loss in very low birth weight infants in incubators
Double-bundle versus single-bundle reconstruction for anterior cruciate ligament rupture in adults
Double-stapled anastomosis versus mucosectomy and handsewn anastomosis in ileal pouch-anal anastomosis for ulcerative colitis or familial adenomatous polyposis
Doubtful effect of lecithin as a treatment for dementia
Doxapram for ventilatory failure due to exacerbations of chronic obstructive pulmonary disease
Doxapram treatment for apnea in preterm infants
Doxapram versus methylxanthine for apnea in preterm infants
Doxazosin for benign prostatic obstruction
Doxorubicin after initial treatment for sarcoma reduces risk of recurrence
Doxycycline plus ivermectin for preventing and treating river blindness (onchocerciasis)
Doxycycline for osteoarthritis
Dr Matthew Page on winning the 2018 Bill Silverman Prize
Dr. Christian Osadnik wins Monash University 2018 Faculty Early Career Research prize for Cochrane Review
Dr. David Tovey awarded Emeritus Editor-in-Chief
Drain use after an open appendectomy for complicated appendicitis
Drain use after pancreatic surgery
Drainage tube placement after lymph gland removal from the armpit for breast cancer
Drains are often used after thyroid operations.
Drains for leg artery surgery
Drains increase the harms to patients undergoing open cholecystectomy
Drains versus no drains after pelvic lymphadenectomy to prevent lymphocyst formation in women with gynaecological cancer
Drama therapy for schizophrenia or schizophrenia-like illnesses
Dressings and securement devices to prevent complications for peripheral arterial catheters
Dressings and securement for central venous catheters (CVCs)
Dressings and topical agents (creams or lotions) for preventing pressure ulcers
Dressings and topical agents (gels, ointments and creams) for treating venous leg ulcers
Dressings and topical agents containing hyaluronic acid for chronic wound healing
Dressings and topical agents for arterial leg ulcers
Dressings and topical agents for donor sites of split-thickness skin grafts
Dressings and topical agents for the management of open wounds after surgical treatment for sacrococcygeal pilonidal sinus
Dressings and topical agents to help surgical wounds heal by secondary intention
Dressings for healing venous leg ulcers
Dressings for the prevention of surgical site infection
Dressings for treating superficial and partial thickness burns
Dressings to treat foot ulcers in people with diabetes
Drinking extra water or other non-caloric beverages for promoting weight loss or preventing weight gain
Driving assessment for maintaining mobility and safety in drivers with dementia
Driving rehabilitation for stroke
Droperidol for psychosis-induced aggression or agitation
Droperidol for the treatment of nausea and vomiting (sickness) in people with advanced disease
Drug and nutritional treatment for McArdle disease
Drug combinations for chronic neuropathic pain in adults
Drug delivery technique using electrical current for the treatment of non-muscle invasive bladder cancer
Drug interventions for deliberately altering blood pressure in acute stroke
Drug interventions for the treatment of obesity in children and adolescents
Drug interventions versus placebo for the treatment of Raynaud’s phenomenon: generic protocol
Drug management for acute tonic-clonic convulsions (fits), including convulsive status epilepticus in children
Drug therapy for chronic idiopathic axonal polyneuropathy
Drug therapy for delirium in terminally ill adults
Drug therapy for Mycetoma
Drug therapy for obstructive sleep apnoea in adults
Drug therapy for pain in amyotrophic lateral sclerosis or motor neuron disease
Drug therapy for treating idiopathic thrombocytopenic purpura during pregnancy
Drug therapy for treating systemic intravascular activation of coagulation in patients with leukemia
Drug therapy to treat high levels of uric acid in individuals with high blood pressure
Drug treatment for borderline personality disorder
Drug treatment for children with bedwetting (nocturnal enuresis) but not including the drug types desmopressin or tricyclics
Drug treatment for depression in multiple sclerosis
Drug treatment for faecal incontinence in adults
Drug treatment for familial amyloid polyneuropathy
Drug treatment for lower urinary tract symptoms in women with voiding dysfunction
Drug treatment for myotonia (delayed muscle relaxation after contraction) in muscle diseases such as myotonic dystrophy and myotonia congenita
Drug treatment for pain in Guillain-Barré syndrome
Drug treatment for respiratory syncytial virus lung infections
Drug treatment for small abdominal aortic aneurysms
Drug treatment for spinal muscular atrophy type I
Drug treatment of recurrent abdominal pain in children
Drug treatment other than corticosteroids, intravenous immunoglobulin and plasma exchange for acute Guillain Barré syndrome
Drug treatments and electronic cigarettes for stopping smoking in pregnancy
Drug treatments for apathy in Alzheimer's disease
Drug treatments for chronic cognitive impairment in traumatic brain injury
Drug treatments for chronic hair-pulling (trichotillomania)
Drug treatments for constipation caused by antipsychotic medications
Drug treatments for dysthymia
Drug treatments for pain in children and young people with life-limiting conditions
Drug treatments for pain relief in hysterosalpingography
Drug treatments for sexual offenders or those at risk of offending
Drug treatments that specifically target ammonia for adults with cirrhosis and hepatic encephalopathy
Drug treatments to ease breathlessness in cystic fibrosis
Drug-based and non-drug-based interventions to improve the bone mineral density in patients living with HIV
Drug-eluting balloon angioplasty versus uncoated balloon angioplasty for stenosis of stents in lower limb arteries
Drug-eluting bead transarterial chemoembolisation for unresectable hepatocellular carcinoma
Drug-eluting stents versus bare metal stents for angina or acute coronary syndromes
Drug-eluting stents versus bare-metal stents for stable ischaemic heart disease
Drug-free management of young children's pain during medical procedures
Drugs (with the exception of botulinum toxin) to treat spasticity after stroke
Drugs against parasites for prevention of Chagas heart disease
Drugs and natural products for self-harm in adults
Drugs and pacemakers for transient loss of consciousness
Drugs as treatment for self-injurious behaviour in adults with intellectual disabilities
Drugs commonly-used for preventing high altitude illness
Drugs for cancer-related fatigue
Drugs for discoid lupus erythematosus
Drugs for general anaesthesia for caesarean section
Drugs for itching in adult palliative care patients
Drugs for motor complications in people with Parkinson´s disease who are already taking levodopa
Drugs for nocturia in adults
Drugs for perineal pain in the early postpartum period: generic protocol
Drugs for preventing blood clot dissolution (antifibrinolytic therapy) to reduce the occurrence of rebleeding in aneurysmal subarachnoid haemorrhage
Drugs for preventing dry mouth and problems with saliva after radiotherapy
Drugs for preventing graft versus host disease
Drugs for preventing headache after a lumbar puncture
Drugs for preventing hepatitis B recurrence after liver transplantation
Drugs for preventing kidney disease in people with diabetes
Drugs for preventing lung cancer in healthy people
Drugs for preventing major morbidity and mortality related to blood pressure and heart rate changes associated with tracheal intubation
Drugs for preventing migraine headaches in children
Drugs for preventing nausea and vomiting after surgery
Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: a network meta-analysis
Drugs for reducing inflammation in people with familial Mediterranean fever
Drugs for reducing iron in patients with acute stroke
Drugs for reducing stomach acid for people with cystic fibrosis
Drugs for the acute treatment of migraine in children and adolescents
Drugs for the prevention and treatment of pruritus in patients receiving neuraxial opioids
Drugs for the prevention of postoperative urinary retention in adults
Drugs for treating Buruli ulcer (Mycobacterium ulcerans disease)
Drugs for treating giardiasis
Drugs for treating giardiasis
Drugs for treating headache after a lumbar puncture
Drugs for treating people with sleepiness during shift work and sleep problems after shift work
Drugs for treating Schistosoma mansoni infection
Drugs for treating urinary schistosomiasis
Drugs for treatment of urinary retention after surgery in adults
Drugs for treatment of very high blood pressure during pregnancy
Drugs improving insulin resistance for non-alcoholic fatty liver disease and/or non-alcoholic steatohepatitis
Drugs in overactive bladder syndrome
Drugs other than those used for epilepsy for treating trigeminal neuralgia
Drugs targeting PI3K/AKT/mTOR pathway for locally-advanced, metastatic or recurrent endometrial cancer
Drugs that aim to prevent the loss of protein or albumin through urine in people with sickle cell disease
Drugs that aim to reduce the loss of water from red blood cells in people with sickle cell disease
Drugs that aim to relieve clinical symptoms of tuberous sclerosis complex
Drugs that increase alertness (psychostimulants) for excessive daytime sleepiness (hypersomnia) in myotonic dystrophy
Drugs that prevent oral bleeding in people using oral anticoagulants undergoing minor oral surgery or dental extractions
Drugs that prevent oral bleeding in people with haemophilia or Von Willebrand disease undergoing minor oral surgery or dental extractions
Drugs that suppress or modify the immune system for dermatomyositis and polymyositis
Drugs that target abnormal growth protein in high-grade, aggressive brain tumours
Drugs that target blood vessels in malignant brain tumours
Drugs to break down blood clots for people with sudden onset peripheral arterial occlusion
Drugs to control the movement of salt in the lungs of people with cystic fibrosis
Drugs to dissolve pulmonary embolism (blood clot in the lungs)
Drugs to help end amphetamine dependence are not very helpful, and more research is needed.
Drugs to help reduce anxiety in people nearing the end of life due to illness
Drugs to improve blood flow for people who have poor blood circulation in the veins of their legs
Drugs to prevent clots after bleeding in the brain
Drugs to prevent heart damage in cancer patients receiving anthracyclines
Drugs to prevent malaria in HIV-positive pregnant women.
Drugs to prevent nausea and vomiting in children and young people undergoing chemotherapy
Drugs to prevent the re-occurrence of narrowing of blood vessels in peripheral arterial disease after the blood vessels have been surgically widened
Drugs to reduce bleeding and transfusion in adults undergoing cardiac surgery: a systematic review and network meta-analysis
Drugs to reduce bleeding and transfusion in major open vascular or endovascular surgery: a systematic review and network meta-analysis
Drugs to suppress the immune system after lung transplantation in people with cystic fibrosis
Drugs to treat acute respiratory distress syndrome in adults
Drugs to treat fibroids
Drugs to treat phantom limb pain in people with missing limbs
Drugs used as add-on therapy to heart procedure following heart attack
Drugs used to lower blood pressure do not reduce sudden death
Drugs used to treat the symptoms of patellofemoral syndrome have little evidence base
Dual antibiotics for bronchiectasis
Dual task training for improving balance and gait in people with stroke
Duct-to-mucosa pancreaticojejunostomy for the prevention of postoperative pancreatic fistula following pancreaticoduodenectomy
Duloxetine can improve the quality of life of patients with stress urinary incontinence, long-term effects of the treatment are unclear.
Duloxetine for generalised anxiety disorder (GAD)
Duloxetine for treating painful neuropathy, chronic pain or fibromyalgia
Duloxetine versus other antidepressive agents for depression
Duodenum-preserving pancreatic resection versus pancreaticoduodenectomy for chronic pancreatitis
Duplex ultrasound for the detection of stenosis after peripheral arterial bypass grafting using autologous vein
Duplex ultrasound for the diagnosis of symptomatic deep vein thrombosis in the lower limb
Duration of 5FU based chemotherapy in adjuvant setting for colorectal cancer should not exceed 6 months.
Duration of antibacterial treatment for uncomplicated urinary tract infection in women
Duration of chemotherapy for metastatic breast cancer
Duration of therapy for tuberculosis in patients infected with Human Immunodeficiency Virus
Duration of treatment for asymptomatic bacteriuria during pregnancy
Dying Matters Awareness Week
Dynamic exercise programs (aerobic capacity and/or muscle strength training) in patients with rheumatoid arthritis
Dynamic exercise therapy for rheumatoid arthritis is effective in increasing aerobic capacity, muscle strength and joint mobility and does not increase disease activity, joint damage or pain.
Dysphagia occurs frequently in Parkinson's disease although patients themselves may be unaware of swallowing difficulties. Speech and language therapists in conjunction with nurses and dietiticians use techniques that aim to improve swallowing and reduce
E-health interventions for anxiety and depression in children and adolescents with long-term physical conditions
Ear drops for the removal of ear wax
Earlier compared to later addition of human milk fortifier to human milk to promote growth in preterm infants
Early (less than 30 days after the start of chemotherapy) or late (more than 30 days after the start of chemotherapy) chest radiotherapy for patients suffering from limited small cell lung cancer
Early (up to seven days) systemic postnatal corticosteroids for preventing bronchopulmonary dysplasia in preterm infants
Early additional food and fluids for healthy breastfed full-term infants
Early administration of inhaled corticosteroids for preventing chronic lung disease in very low birth weight preterm neonates
Early amniocentesis versus transabdominal chorion villus sampling for prenatal diagnosis
Early amniotomy and early oxytocin for delay in first stage spontaneous labour compared with routine care
Early and late adverse effects on the kidney after treatment for childhood cancer
Early Bird Colloquium Registration Deadline: July 25
Early bird registration and stipends now open for the Global Evidence Summit
Early bird registration now open for Cochrane Colloquium Santiago
Early birth compared with waiting for birth in babies who are thought to be coping poorly towards the end of pregnancy
Early birth for babies with gastroschisis
Early combination therapy with levodopa and dopamine agonist for preventing motor fluctuations in Parkinson's disease
Early compared with delayed oral fluids and food after caesarean section
Early developmental intervention programmes provided post hospital discharge to prevent motor and cognitive impairment in preterm infants
Early discharge of preterm infants from hospital
Early discharge with home support of gavage feeding for stable preterm infants who have not established full oral feeds
Early elbow movement compared to delayed elbow movement after a broken elbow in adults
Early emergency department treatment of acute asthma with systemic corticosteroids
Early erythropoiesis-stimulating agents in preterm or low birth weight infants
Early excision and grafting for burns
Early full enteral feeding for preterm or low birth weight infants
Early intensive behavioral intervention (EIBI) for increasing functional behaviors and skills in young children with autism spectrum disorders (ASD)
Early intervention (movement or active exercise) for critically ill adults in the intensive care unit
Early intervention delivered by parents for young children with autism spectrum disorders
Early intervention delivered by parents to young children with autism spectrum disorder
Early Intervention for psychosis
Early interventions for people at risk of developing psychosis
Early intravenous nutrition for the prevention of neonatal jaundice
Early introduction of lipids to parenterally-fed preterm infants
Early laparoscopy versus observation for patients with acute abdominal pain
Early lens extraction compared to standard treatment in acute primary angle closure
Early light reduction for preventing retinopathy of prematurity in very low birth weight infants
Early nasal intermittent positive pressure ventilation (NIPPV) versus early nasal continuous positive airway pressure (NCPAP) for preterm infants
Early nutritional therapy for malnourished or nutritionally at-risk adult medical inpatients
Early or delayed removal of gallbladder by key-hole surgery after a sudden episode of gallstone-related pancreatitis
Early or delayed surgical removal of appendix in people with symptomatic complicated appendicitis
Early palliative care for adults with advanced cancer
Early palliative interventions for improving outcomes in people with a primary malignant brain tumour and their carers
Early pharmacological interventions for acute traumatic stress symptoms: a network meta-analysis
Early pharmacological interventions for preventing post-traumatic stress disorder (PTSD): a network meta-analysis
Early planned removal of umbilical venous catheters to prevent infection in newborn infants
Early planned removal versus expectant management of peripherally inserted central catheters to prevent infection in newborn infants
Early postnatal discharge from hospital for healthy mothers and term infants
Early pregnancy screening for identification of undiagnosed pre-existing diabetes to improve maternal and infant health
Early psychological interventions to treat acute traumatic stress symptoms
Early referral to a specialist doctor for people with kidney disease
Early registration for Cochrane Colloquium Edinburgh extended until Friday 22 June
Early removal versus expectant management of central venous catheters in newborn infants with bloodstream infection