Do inhaled corticosteroids reduce growth in children with persistent asthma?
Do inhaled steroids increase the risk of pneumonia in people with chronic obstructive pulmonary disease (COPD)?
Do injectable pneumococcal vaccines prevent pneumonia in people with COPD?
Do interventions in families prevent children and adolescents from starting to smoke
Do interventions that reduce the cost of smoking cessation treatment increase quit rates, quit attempts or use of treatments?
Do interventions to enhance one-to-one support provided by partners, family members, or 'buddies' help smokers quit?
Do magnesium sulfate infusions reduce the need for hospital admission in adults with acute asthma?
Do magnesium sulfate infusions reduce the need for hospital admission in children with acute asthma?
Do media campaigns prevent young people from using illicit drugs?
Do medications used to treat depression help smokers who are trying to quit
Do medicinal interventions reduce radiation-related bone fractures and risk of avascular necrosis in adults undergoing pelvic radiotherapy?
Do nasal decongestants used alone relieve cold symptoms?
Do newer laser treatments work better than standard laser treatments for proliferative diabetic retinopathy?
Do nonsteroidal anti-inflammatory drugs (NSAIDs) increase the risk of bleeding in children having their tonsils out?
Do nutritional interventions reduce gastrointestinal toxicity in adults undergoing radical pelvic radiotherapy?
Do opioid antagonists such as naltrexone help people to stop smoking?
Do organizational changes to support people quitting smoking improve services and help more people to quit?
Do painkillers rubbed on the skin really work?
Do PARP inhibitors improve survival in women with ovarian cancer and what are the side effects?
Do people recover from exacerbations of chronic obstructive pulmonary disease (COPD) better in their own home than in the hospital emergency room?
Do people with asthma have fewer serious adverse events when taking formoterol and inhaled corticosteroids or salmeterol and inhaled corticosteroids?
Do people's genes affect how effective medicines can be in helping people to quit smoking?
Do pharmacotherapies which reduce anxiety help smokers to quit
Do printed self-help materials help people to quit smoking?
Do Quit and Win contests encourage people to give up smoking
Do school tobacco policies prevent uptake of smoking?
Do smoking bans at an institutional level help to stop people smoking?
Do speed cameras reduce road traffic crashes, injuries and deaths?
Do statins prevent kidney failure in adults after surgery where cardiac bypass is used?
Do supportive, educational and/or behavioural interventions improve usage of CPAP machines by adults with obstructive sleep apnoea (OSA)?
Do systemic corticosteroids improve treatment outcomes in flare-ups of chronic obstructive pulmonary disease?
Do tobacco cessation interventions provided during substance abuse treatment or recovery help tobacco users to quit?
Do vaginal packing, tranexamic acid, interventional radiology or other interventions control vaginal bleeding in women with advanced cervical cancer?
Do ventilators that manage the reduction of ventilator support (weaning) reduce the duration of weaning compared to strategies managed by clinicians?
Do weight loss programs have beneficial effects on asthma outcomes in people with asthma?
Do workplace pedometer interventions increase physical activity?
Doctors and patients making decisions together could reduce the number of antibiotics prescribed for acute respiratory infections
Does 5-ASA prevent the recurrence of diverticulitis?
Does a combination of stop smoking medication and behavioural support help smokers to stop?
Does a group of drugs known as calcium channel blockers reduce mortality and unfavourable complications in patients with traumatic brain injury?
Does a local anaesthetic injection in children and young people having dental treatment under general anaesthetic reduce pain after treatment?
Does adding a long-acting muscarinic antagonist (LAMA) to an inhaled steroid help people with uncontrolled asthma more than an inhaled steroid alone?
Does adding antileukotriene agents to usual care when people are suffering an asthma attack in the emergency department help?
Does adding tiotropium, a long-acting muscarinic antagonist (LAMA), to combination therapy (LABA/ICS) help to control asthma?
Does administering colony-stimulating factors plus antibiotics in people with fever and low white cell count reduce hospitalization?
Does advice from doctors encourage people who smoke to quit
Does altering dietary salt intake aid in the prevention and treatment of diabetic kidney disease?
Does altering the dose of inhaled corticosteroids make a difference in growth among children with asthma?
Does an aminophylline injection in addition to bronchodilators for an asthma attack improve lung function and other outcomes or cause harm?
Does banning or restricting advertising for alcohol result in less drinking of alcohol?
Does breastfeeding reduce vaccination pain in babies aged 1 to 12 months?
Does chewing gum after a caesarean section lead to quicker recovery of bowel function?
Does chromoscopy (dye-spraying) improve rates of polyp detection when compared to conventional colonoscopy?
Does clonidine help smokers to quit
Does communicating DNA-based risk estimates motivate people to change their behaviour?
Does controlling exposure to house dust mites improve asthma?
Does Daikenchuto reduce postoperative ileus in persons undergoing elective abdominal surgery?
Does daily sedation interruption reduce the time critically ill adults spend on breathing machines compared to other sedation strategies?
Does daily treatment with formoterol result in more serious adverse events compared to placebo or daily salbutamol?
Does daily treatment with salmeterol result in more serious adverse events compared with placebo or a salbutamol?
Does delaying cord clamping or using cord milking at birth improve the health of babies born too early?
Does delivery of home care by outreach nurses improve outcomes for people with chronic obstructive pulmonary disease?
Does denser compared to normal bupivacaine, given as a lower back injection, give more effective and safer anaesthesia during caesarean section
Does dermoscopy improve the accuracy of diagnosing basal cell or squamous cell skin cancer (BCC or cSCC) compared to using the naked eye alone?
Does dietary fibre prevent the recurrence of colorectal adenomas and carcinomas?
Does electromagnetic field stimulation help heal fractures that are failing or have failed to heal?
Does enhanced external counterpulsation reduce symptoms of chronic and refractory angina pectoris?
Does extended-field radiotherapy reduce death from locally advanced cervical cancer and what are the side effects?
Does giving chemotherapy before surgery improve survival or quality of life for women with advanced ovarian epithelial cancer?
Does giving chemotherapy straight away or waiting for symptoms prolong life for persons who have incurable colorectal cancer without symptoms?
Does giving chemotherapy, radiotherapy or both improve survival in people with rare (anaplastic oligodendrogliomas and oligoastrocytomas) brain tumours?
Does giving daily small, steadily increasing amounts of egg protein help people with egg allergy?
Does giving patients carbohydrate supplements before planned surgery lead to improved recovery?
Does giving people feedback on the effects of smoking on their body help them quit smoking?
Does group therapy improve well-being in people living with HIV?
Does haemodialysis membrane type influence outcomes in people with kidney disease?
Does HPV vaccination prevent the development of cervical cancer? Are there harms associated with being vaccinated?
Does hyperbaric oxygen therapy improve outcome after heart attack?
Does hyperbaric oxygen therapy improve the survival and quality of life in patients with traumatic brain injury?
Does hypnotherapy help people who are trying to stop smoking?
Does individually-delivered counselling help people to stop smoking?
Does isolating the site of a dental restoration during treatment improve the performance of the restoration?
Does legislation to ban smoking reduce exposure to secondhand smoke and smoking behaviour?
Does mecamylamine help people to stop smoking
Does monitoring oxygen level with a pulse oximeter during and after surgery improve patient outcomes?
Does more support increase success amongst people using medications to quit smoking?
Does motivational interviewing help people to quit smoking?
Does Nicobrevin help people to stop smoking
Does perioperative blood transfusion affect the recurrence rate of potentially curable operations for colorectal cancer?
Does personalised advice via computer or mobile devices reduce heavy drinking?
Does physical exercise have beneficial or harmful effects in cirrhosis?
Does platelet-rich plasmapheresis (PRP) reduce the need for donor blood
Does pre-transfusion washing of red blood cells for preterm babies improve their health outcomes?
Does prophylactic mesh placement around a stoma prevent the development of future hernia and general patient discomfort?
Does reducing the amount of salt in a diet improve asthma symptoms?
Does reduction of dialysate temperature affect blood pressure during haemodialysis?
Does reminding people to have vaccinations increase the number of people who receive vaccinations?
Does silver acetate help people stop smoking
Does smoking in a way that is unpleasant help smokers to quit
Does special assessment of older people getting surgery improve their recovery after surgery?
Does statin therapy improve survival or reduce risk of heart disease in people on dialysis?
Does subfascial endoscopic perforator surgery (leg-vein surgery) help heal venous leg ulcers?
Does supplementation of human milk with calcium and phosphorus improve growth and development in preterm infants?
Does support and intervention from nurses help people to stop smoking?
Does taking a supplement of myo-inositol work as an effective treatment for women who develop diabetes during pregnancy?
Does taking inhaled steorids either before or after being intubated (having a tube down the throat to help you breathe) prevent the painful swelling that can result?
Does telephone counselling help people stop smoking?
Does the administration of nalbuphine provide effective and safe postoperative pain treatment in children?
Does the perioperative administration of tramadol provide effective and safe postoperative analgesia in children?
Does the prescription of low-calorie (hypocaloric) nutrition support improve the recovery of critically-ill adult patients?
Does the speed of injection make a difference in the amount of pain and bruising in people receiving heparin injections?
Does the timing and route of nutritional support have an effect on survival and disability in head-injured patients?
Does tobacco advertising and promotion make it more likely that adolescents will start to smoke
Does tranexamic acid given before an operation reduce blood loss for women with advanced ovarian cancer?
Does treating obstructive sleep apnoea in children who also have chronic cough improve their cough?
Does treating Streptococcal throat infection help improve psoriasis?
Does treatment for gum disease help people with diabetes control blood sugar levels?
Does use of an electronic health record improve the delivery of stop smoking treatment to patients?
Does written information reduce antibiotic use for upper airway infections among people treated in primary care settings?
Domestic violence screening and intervention programmes for adults with dental or facial injury
Domiciliary oxygen for chronic obstructive pulmonary disease
Domiciliary oxygen for interstitial lung disease
Dominican Republic will now have free access to Cochrane Reviews
Donepezil for dementia in people with Down Syndrome
Donepezil for people with dementia due to Alzheimer's disease
Donor organ preservation techniques for kidney transplantation
Donor versus no donor comparison of hematopoietic cell transplantation for adult acute lymphoblastic leukemia in first complete remission
Dopamine agents for hepatic encephalopathy
Dopamine agonist therapy in early Parkinson's disease
Dopamine agonists for idiopathic hyperprolactinaemia and prolactinoma in adults
Dopamine agonists for preventing future miscarriage in women with high prolactin levels and a history of recurrent miscarriage
Dopamine agonists for restless legs syndrome
Dopamine agonists for the treatment of people who misuse cocaine
Dopamine agonists for traumatic brain injury
Dopamine agonists to prevent ovarian hyperstimulation syndrome in women undergoing assisted reproduction technology
Dopamine for prevention of morbidity and mortality in term newborn infants with suspected perinatal asphyxia
Dopamine transporter imaging for the diagnosis of dementia with Lewy bodies
Dopamine versus dobutamine for hypotensive preterm infants
Dopamine versus no treatment to prevent renal dysfunction in indomethacin-treated preterm newborn infants
Dopaminergic agents versus control for enhancing stroke recovery and rehabilitation
Dopaminergic antagonists for alcohol dependence
Doppler trans-thoracic echocardiography for detection of pulmonary hypertension in adults
Doppler ultrasound for fetal assessment in high risk pregnancies
Doppler ultrasound of blood vessels in the placenta and uterus of pregnant women as a way of improving outcome for babies and their mothers
Doppler ultrasound of fetal blood vessels in normal pregnancies
Doppler ultrasound of fetal vessels in pregnancies at increased risk of complications
Doppler ultrasound, CT angiography, MR angiography, and contrast-enhanced MR angiography versus intra-arterial angiography for moderate and severe carotid stenosis in symptomatic patients
Dornase alfa, an inhaled drug, for treating lung disease in cystic fibrosis
Dosage intervals of amoxicillin for the treatment of acute middle ear infection
Dose-escalated radiotherapy for clinically localised and locally advanced prostate cancer
Double gloving to reduce surgical cross-infection
Double wall versus single wall incubator for reducing heat loss in very low birth weight infants in incubators
Double-bundle versus single-bundle reconstruction for anterior cruciate ligament rupture in adults
Double-stapled anastomosis versus mucosectomy and handsewn anastomosis in ileal pouch-anal anastomosis for ulcerative colitis or familial adenomatous polyposis
Doubtful effect of lecithin as a treatment for dementia
Doxapram for ventilatory failure due to exacerbations of chronic obstructive pulmonary disease
Doxapram treatment for apnea in preterm infants
Doxapram versus methylxanthine for apnea in preterm infants
Doxazosin for benign prostatic obstruction
Doxorubicin after initial treatment for sarcoma reduces risk of recurrence
Doxycycline plus ivermectin for preventing and treating river blindness (onchocerciasis)
Doxycycline for osteoarthritis
Dr Matthew Page on winning the 2018 Bill Silverman Prize
Dr. Christian Osadnik wins Monash University 2018 Faculty Early Career Research prize for Cochrane Review
Drain use after an open appendectomy for complicated appendicitis
Drain use after pancreatic surgery
Drainage tube placement after lymph gland removal from the armpit for breast cancer
Drains are often used after thyroid operations.
Drains for leg artery surgery
Drains increase the harms to patients undergoing open cholecystectomy
Drains versus no drains after pelvic lymphadenectomy to prevent lymphocyst formation in women with gynaecological cancer
Drama therapy for schizophrenia or schizophrenia-like illnesses
Dressings and securement devices to prevent complications for peripheral arterial catheters
Dressings and securement for central venous catheters (CVCs)
Dressings and topical agents (creams or lotions) for preventing pressure ulcers
Dressings and topical agents (gels, ointments and creams) for treating venous leg ulcers
Dressings and topical agents containing hyaluronic acid for chronic wound healing
Dressings and topical agents for arterial leg ulcers
Dressings and topical agents for donor sites of split-thickness skin grafts
Dressings and topical agents for the management of open wounds after surgical treatment for sacrococcygeal pilonidal sinus
Dressings and topical agents to help surgical wounds heal by secondary intention
Dressings for healing venous leg ulcers
Dressings for the prevention of surgical site infection
Dressings for treating superficial and partial thickness burns
Dressings to treat foot ulcers in people with diabetes
Drinking extra water or other non-caloric beverages for promoting weight loss or preventing weight gain
Driving assessment for maintaining mobility and safety in drivers with dementia
Driving rehabilitation for stroke
Droperidol for psychosis-induced aggression or agitation
Droperidol for the treatment of nausea and vomiting (sickness) in people with advanced disease
Drug and nutritional treatment for McArdle disease
Drug combinations for chronic neuropathic pain in adults
Drug delivery technique using electrical current for the treatment of non-muscle invasive bladder cancer
Drug interventions for deliberately altering blood pressure in acute stroke
Drug interventions for the treatment of obesity in children and adolescents
Drug interventions versus placebo for the treatment of Raynaud’s phenomenon: generic protocol
Drug management for acute tonic-clonic convulsions (fits), including convulsive status epilepticus in children
Drug therapy for chronic idiopathic axonal polyneuropathy
Drug therapy for delirium in terminally ill adult patients
Drug therapy for Mycetoma
Drug therapy for obstructive sleep apnoea in adults
Drug therapy for pain in amyotrophic lateral sclerosis or motor neuron disease
Drug therapy for treating idiopathic thrombocytopenic purpura during pregnancy
Drug therapy for treating systemic intravascular activation of coagulation in patients with leukemia
Drug therapy to treat high levels of uric acid in individuals with high blood pressure
Drug treatment for borderline personality disorder
Drug treatment for children with bedwetting (nocturnal enuresis) but not including the drug types desmopressin or tricyclics
Drug treatment for depression in multiple sclerosis
Drug treatment for faecal incontinence in adults
Drug treatment for lower urinary tract symptoms in women with voiding dysfunction
Drug treatment for myotonia (delayed muscle relaxation after contraction) in muscle diseases such as myotonic dystrophy and myotonia congenita
Drug treatment for pain in Guillain-Barré syndrome
Drug treatment for respiratory syncytial virus lung infections
Drug treatment for small abdominal aortic aneurysms
Drug treatment for spinal muscular atrophy type I
Drug treatment for spinal muscular atrophy types II and III
Drug treatment of recurrent abdominal pain in children
Drug treatment other than corticosteroids, intravenous immunoglobulin and plasma exchange for acute Guillain Barré syndrome
Drug treatments for apathy in Alzheimer's disease
Drug treatments for chronic cognitive impairment in traumatic brain injury
Drug treatments for chronic hair-pulling (trichotillomania)
Drug treatments for constipation caused by antipsychotic medications
Drug treatments for dysthymia
Drug treatments for pain in children and young people with life-limiting conditions
Drug treatments for pain relief in hysterosalpingography
Drug treatments for sexual offenders or those at risk of offending
Drug treatments for stopping smoking in pregnancy
Drug treatments that specifically target ammonia for adults with cirrhosis and hepatic encephalopathy
Drug treatments to ease breathlessness in cystic fibrosis
Drug-based and non-drug-based interventions to improve the bone mineral density in patients living with HIV
Drug-eluting balloon angioplasty versus uncoated balloon angioplasty for stenosis of stents in lower limb arteries
Drug-eluting bead transarterial chemoembolisation for unresectable hepatocellular carcinoma
Drug-eluting stents versus bare metal stents for angina or acute coronary syndromes
Drug-eluting stents versus bare-metal stents for stable ischaemic heart disease
Drug-free management of young children's pain during medical procedures
Drugs (with the exception of botulinum toxin) to treat spasticity after stroke
Drugs against parasites for prevention of Chagas heart disease
Drugs and natural products for self-harm in adults
Drugs and pacemakers for transient loss of consciousness
Drugs as treatment for self-injurious behaviour in adults with intellectual disabilities
Drugs commonly-used for preventing high altitude illness
Drugs for cancer-related fatigue
Drugs for discoid lupus erythematosus
Drugs for general anaesthesia for caesarean section
Drugs for itching in adult palliative care patients
Drugs for motor complications in people with Parkinson´s disease who are already taking levodopa
Drugs for nocturia in adults
Drugs for perineal pain in the early postpartum period: generic protocol
Drugs for preventing blood clot dissolution (antifibrinolytic therapy) to reduce the occurrence of rebleeding in aneurysmal subarachnoid haemorrhage