Index

The relative benefits of oral and intravenous fluoropyrimidines in the palliative treatment of colo-rectal cancer are uncertain. Large studies have suggested that response rates to the oral fluoropyrimidines are higher and that the oral agents are better
The relative safety and effectiveness of different epoetin drugs for treating anaemia in people with chronic kidney disease
The repair of a defect in the anterior abdominal wall with minimal invasive (laparoscopic) or conventionally (open) technique
The review found that both, D&C and vacuum aspiration, are safe and effective methods for first trimester termination of pregnancy and complications are rare.
The risk of heart attack and stroke in women using birth control pills
The risk of infertility in women with IBD who have had surgery
The role of aerobic physical exercise for adults with haematological malignancies
The role of allogeneic stem cell transplantation for patients with advanced stage primary cutaneous T-cell lymphoma
The role of bortezomib treatment for patients with multiple myeloma
The role of brain radiotherapy (X-rays) in the treatment of lymphoma in the brain
The role of chemotherapy additional to high-dose methotrexate for treatment of patients with primary central nervous system lymphoma
The role of concomitant extracorporeal photopheresis for the treatment of chronic graft-versus-host disease after allogeneic haematopoietic stem cell transplantation
The role of high-frequency oscillations in epilepsy surgery planning
The role of interleukin-2 as maintenance therapy in children and adults with acute myeloid leukaemia in first complete remission
The role of iron in the management of chemotherapy-induced anemia in cancer patients receiving erythropoiesis-stimulating agents
The role of MRI in the early diagnosis of Alzheimer’s disease or other dementias in persons with mild cognitive impairment (MCI)
The role of prophylactic immunoglobulins in hematological malignancies
The role of removing lymph nodes as part of standard surgery for endometrial cancer
The role of sealants for achieving anastomotic hemostasis in vascular surgery
The role of surgical assessment of lymph nodes before treatment for women with locally advanced cervical cancer
The role of the monoclonal anti-CD20 antibodies for treatment of patients with chronic lymphocytic leukaemia
The role of the monoclonal antibody alemtuzumab for treatment of people with chronic lymphocytic leukaemia
The role of twice versus three times daily heparin dosing for thromboembolism prophylaxis in general medical patients admitted to the hospital
The role of voluntary counseling and testing (VCT) in changing risk behaviors related to HIV
The routine use of traction before surgery in adults with hip fracture
The safety and effectiveness of extending anticoagulant treatment for people who have been treated for blood clots
The Society for Research Synthesis Methodology presents awards to Cochrane contributors
The SPf66 vaccine has little or no effect on preventing malaria
The statement of principles for consumer involvement in Cochrane
The technique popularly known as 'liberation procedure' for treatment of venous stenoses (CCSVI) in the brain of people with MS
The Thomas C Chalmers Award - 2018 Award Winner, Adriani Nikolakopoulou
The Thomas C Chalmers Award - 2018 Award Winner, Leonie Van Grootel
The timing of inhalation of dornase alfa in people with cystic fibrosis
The timing of inhalation of hypertonic saline in people with cystic fibrosis
The treatment of cervical pre-cancer (CIN) with anti-inflammatory agents to induce regression and prevent the progression to cervical cancer
The use of analgesia for acute abdominal pain (AAP) does not mask clinical findings, nor does it delay diagnosis.
The use of anti-inflammatory corticosteroids for treating acute worsening in people with multiple sclerosis
The use of antiarrhythmics prior to cardioversion or catheter ablation for atrial fibrillation
The use of anticoagulants to prevent deep venous thrombosis and pulmonary embolism following surgery for abdominal aortic aneurysm
The use of antiepileptic drugs to prevent seizures following brain surgery
The use of biocompatible dialysis membranes compared with biocompatible membranes does not appear to have a different effect on mortality in patients with acute renal failure (ARF)
The use of blunt needles compared to sharp needles for preventing needle stick injuries in surgical staff
The use of bypassing agents for preventing bleeding in people with hemophilia with inhibitors
The use of colony-stimulating factors in the supportive care of patients with acute myelogenous leukemia (AML)
The use of computed tomography angiography (CTA) to confirm the clinical diagnosis of brain death
The use of decongestants and antihistamines for the treatment of acute otitis media in children
The use of different treatment for incoordination of limb movement (ataxia) or tremor in people with multiple sclerosis
The use of drugs to manage symptoms in people with arthritis related to cystic fibrosis
The use of drugs to slow or stop progression of arthritis related to cystic fibrosis
The use of epinephrine (adrenaline) in the management of transient tachypnea of the newborn
The use of erythropoietin improve anaemia and reduces blood transfusions in surgery for cancer of the large bowel.
The use of glatiramer acetate (Copaxone ®) in people with multiple sclerosis
The use of hormonal treatment in relapsed epithelial ovarian cancer
The use of hyaluronic acid/carboxymethyl cellulose (HA/CMC) membrane, reduces the incidence, extent and severity of adhesions in the abdomen.
The use of immunoglobulins (antibodies) for treating people with multiple sclerosis
The use of incentive spirometry for preventing pulmonary complications in adults people undergoing coronary artery bypass graft surgery
The use of interferons for treating people with the relapsing-remitting form of multiple sclerosis
The use of intravenous antibiotics to treat pulmonary exacerbations in people with cystic fibrosis
The use of lacosamide in partial epilepsy: Does it work and is it harmful?
The use of light as a therapy for acne
The use of machines to preserve kidneys from deceased donors prior to transplantation
The use of medication to treat people with antisocial personality disorder
The use of melatonin as an adjunctive treatment for epilepsy
The use of methotrexate, an immunomodulator drug, for treating people with multiple sclerosis
The use of Nitrous Oxide gas during Colonoscopy procedures
The use of omega-3 supplements in people with cystic fibrosis
The use of oral protein calorie supplements in children with chronic disease
The use of penicillamine in patients with Wilson's disease.
The use of pregabalin analgesia for patients with chronic prostatitis/chronic pelvic pain syndrome
The use of probiotics to prevent Clostridium difficile diarrhea associated with antibiotic use
The use of recombinant growth hormone to improve growth and health in children and young adults with cystic fibrosis
The use of regular vitamin A or vitamin A-like preparations for children and adults with cystic fibrosis
The use of regular vitamin D preparations for children and adults with cystic fibrosis
The use of retinoids (vitamin A derivatives) to prevent progression of cervical intra-epithelial neoplasia (CIN)
The use of Rizatriptan to treat acute migraine in adults
The use of salbutamol (albuterol) in the management of transient tachypnea of the newborn
The use of sapropterin to lower phenylalanine concentration in blood in people with phenylketonuria.
The use of sealants after lung cancer resection reduce postoperative air leaks and, in many cases, the length of hospitalization
The use of standing devices for boys with Duchenne muscular dystrophy
The use of Statins, cholesterol lowering agents, in patients with multiple sclerosis (MS)
The use of telephone for the delivery of HIV testing results
The use of the anticoagulant antithrombin to reduce the risk of intraventricular hemorrhage (i.e. bleeding in the brain) in very preterm infants
The use of the anticoagulant heparin to reduce the risk of intraventricular haemorrhage (i.e. bleeding in the brain) in very preterm infants
The use of the immunosuppressive drug mitoxantrone (MX) in people with multiple sclerosis (MS)
The use of the iron chelator deferiprone in people with thalassaemia who are dependent on blood transfusions
The use of the monoclonal antibody Natalizumab (NTZ) in patients with relapsing remitting multiple sclerosis (RRMS)
The use of the monoclonal antibody rituximab in patients with relapsing remitting multiple sclerosis (RRMS)
The use of the sodium channel blockers in people with multiple sclerosis (MS)
The use of the telephone for the delivery of HIV prevention interventions
The use of the telephone to improve the health of people with HIV infection
The use of vibrating devices to help people with cystic fibrosis clear their airways of mucus
The use of video devices in assisting the placement of breathing tube in babies
The use of vitamin E in the treatment of mild cognitive impairment and Alzheimer's disease (AD)
The usefulness of protocols for reducing the time children spend mechanically ventilated in the intensive care unit
The usefulness of protocols for reducing the time newborn infants spend on mechanical ventilation in the neonatal intensive care unit
The usefulness of weaning protocols for reducing the time critically ill adult patients spend on mechanical ventilation
The WHO Health Promoting School framework for improving the health and well-being of students and their academic achievement
Theophylline, aminophylline, caffeine and analogues for acute ischaemic stroke
Theory-based behavioural interventions for prediabetic state and people with diabetes mellitus
Therapeutic and prophylactic drug interventions for Schistosomiasis japonicum
Therapeutic communities for substance related disorder
Therapeutic communities with aftercare in secure settings may reduced drug misuse and criminal activity.
Therapeutic drug monitoring of antiretroviral medications for people with HIV
Therapeutic exercise for people with amyotrophic lateral sclerosis or motor neuron disease
Therapeutic hypothermia as a neuroprotective therapy after cardiopulmonary arrest in children
Therapeutic interventions for Burkitt lymphoma in children
Therapeutic interventions for daytime somnolence in Parkinson's disease
Therapeutic interventions for sleep disorders in Parkinson's disease
Therapeutic monitoring of antiepileptic drugs for epilepsy
Therapeutic touch for anxiety disorders
Therapeutic touch therapy for healing acute wounds.
Therapeutic ultrasound for acute ankle sprains
Therapeutic ultrasound for carpal tunnel syndrome
Therapeutic ultrasound for chronic low-back pain
Therapeutic ultrasound for chronic rhinosinusitis
Therapeutic ultrasound for osteoarthritis
Therapeutic ultrasound for postpartum perineal pain and dyspareunia
Therapeutic ultrasound for soft-tissue injuries of the elbow
Therapeutic vaccines for advanced non-small cell lung cancer
Therapies for BCG induced disease in children
Therapist-delivered distance cognitive behavioural therapy for anxiety disorders in adults
Therapy for inclusion body myositis
Therapy for treating HIV infection in pregnant women who require treatment for their own health
Therapy for treatment and prevention of pouchitis
Therapy-based rehabilitation services for patients living at home more than one year after stroke
Therapy-based rehabilitation services for stroke patients at home
There is currently insufficient evidence of the effects of Huperzine A for Alzheimer's disease (AD).
There is currently no evidence of effects of heparin and related substances for preventing the onset of diabetic kidney disease (DKD)
There is currently no evidence to determine the best way to treat Mandrax dependence in adults.
There is currently no high quality evidence to support the use of Huperzine A for the treatment of vascular dementia.
There is good evidence that estrogen or combined estrogen and progestagen therapy does not protect against a decline in overall cognitive functioning of older postmenopausal women with normal intellectual ability
There is good evidence that heparin prevents deep vein thrombosis (DVT) after major gynaecological surgery
There is high level evidence to support the safety and effectiveness of Botulinum toxin -A (BoNT-A) as an adjunct to managing the upper limb in children with cerebral palsy.
There is inadequate evidence to evaluate the effect of occupational therapy for people with Parkinson's disease.
There is insufficent evidence to recommend the use of bright light therapy in dementia
There is insufficient evidence for the use of carbohydrates to improve cognitive performance in older adults with normal or mild cognitive impairment
There is insufficient evidence from randomised controlled trials to assess efficacy of surgical and non-surgical interventions for Morton's neuroma. More research is needed.
There is insufficient evidence on whether additional steroids are required at the time of surgery for patients with adrenal insufficiency
There is insufficient evidence that radiotherapy works as well as surgery for treating groin nodes in early vulvar cancer.
There is insufficient evidence to compare equivalence of effect between fully intermittent and daily treatment in adult patients with pulmonary tuberculosis.
There is insufficient evidence to estimate the likely benefits, harms and costs of institutional or at-home care for functionally dependent older people.
There is insufficient evidence to suggest that enteral tube feeding is beneficial in patients with advanced dementia. Data are lacking on the adverse effects of this intervention
There is insufficient evidence to support or refute D-penicillamine for patients with primary sclerosing cholangitis
There is insufficient evidence to support the use of acupuncture for the symptomatic treatment of restless legs syndrome.
There is insufficient evidence to support the use of hyperbaric oxygen for treatment of patients with carbon monoxide poisoning
There is limited evidence from three small trials suggesting that the correction of metabolic acidosis trials may have some beneficial effects on both protein and bone metabolism
There is limited evidence to support the assumption that the care of people with dementia in special care units is superior to care in traditional nursing units.
There is no compelling evidence to support the use of the herbal medicines identified in this review for treatment of HIV infection and AIDS.
There is no convincing evidence from randomized controlled trials that blood pressure lowering in late life prevents the development of cognitive impairment and dementia in patients without apparent prior cerebrovascular disease.
There is no convincing evidence that Ginkgo biloba is efficacious for dementia and cognitive impairment
There is no evidence from randomised controlled trials for or against the use of 'Yizhi capsule' as a treatment for vascular dementia
There is no evidence of a positive effect that estrogen replacement therapy can maintain cognitive function for a longer period of time (> five months) in women with Alzheimer's disease
There is no evidence of difference in clinical and microbiological efficacy of quinolones for uncomplicated acute cystitis in women, but there is some evidence of differences in occurrence and range of adverse reactions.
There is no evidence that adjunctive therapies for AIDS dementia are effective, though they are well-tolerated and safe.
There is no evidence that aspirin improves the symptoms of vascular dementia
There is no evidence that hormonal suppression either before or after surgery for endometriosis is associated with a benefit
There is no evidence that MPACs (PBT1 or PBT2) are of benefit in Alzheimer's dementia
There is no evidence that radiotherapy could help to cure or to prolong the survival of patients with malignant pleural mesothelioma
There is no evidence to indicate whether placement of a shunt to remove fluid is effective in the management of normal pressure hydrocephalus
There is no evidence to recommend that patients with non-small cell lung cancer receive prophylactic radiotherapy to the brain following potentially curative treatment with surgery or radiotherapy
There is no evidence to support azathioprine for patients with primary biliary cirrhosis
There is no evidence to support routine drain use after liver resections
There is no evidence to support the use of donepezil for patients with mild cognitive impairment (MCI). The putative benefits are minor, short lived and associated with significant side effects
There is no strong evidence that any of the variations in surgical technique described in this review for placing implants have superior success rates
There is not enough evidence about the safety and effectiveness of amantadine for people with dyskinesia in Parkinson's disease.
There is not enough evidence about the safety and effectiveness of amantadine for people with Parkinson's disease.
There is not enough evidence on whether pelvic floor exercises can prevent incontinence after childbirth or prostate surgery, but the evidence is most promising for women at high risk after childbirth.
There is not enough evidence that anti-reflux therapies are effective in treating hoarseness
There is not enough evidence to determine if anticoagulants safely prevent blood clots in patients with chronic heart failure who are in normal heart rhythm
There is not enough evidence to establish precise criteria for the prescription of prosthetic ankle-foot mechanisms in individuals with a lower limb amputation.
There is not enough evidence to show that lowering body temperature can reduce nerve damage during coronary artery bypass surgery.
There is not enough high quality evidence to show that dietary magnesium supplementation during pregnancy is beneficial
There is some evidence that human growth hormone may help reduce growth problems in children with chronic kidney disease
Thermotherapy (heat treatment) for treating osteoarthritis of the knee
Thermotherapy (heat treatment) for treating rheumatoid arthritis
Thiamine for prevention and treatment of Wernicke-Korsakoff syndrome in people who abuse alcohol
Thiazide diuretics and hip fracture
Thiazide diuretics for the treatment of high blood pressure
Thiazides best first choice for hypertension
Thiazolidinediones for dementia and mild cognitive impairment
Thienopyridine derivatives versus aspirin for preventing stroke and other serious vascular events in high vascular risk patients
Thioridazine for schizophrenia
Third-line systemic chemotherapy for small cell lung cancer
Third-line systemic treatment for non-small cell lung cancer
This review addresses two questions. First, "Does the oral administration of water soluble contrast media followed by serial abdominal radiographs during the following 24 hours predict the need for early operation or resolution?"
This review aimed to assess how effective contraceptive implants were at preventing pregnancy and how acceptable women found them compared to other methods of contraception.
This review assesses the usefulness surgery for anal fissure, a painful ulcer at the anal opening, by comparing the efficacy of various surgical procedures and how likely they are to result in complications.
This review compares the safety and effectiveness of two of the most popular treatments for haemorrhoids, rubber band ligation (RBL) and excisional haemorrhoidectomy (EH).
This review compares two injectable hormonal contraceptives containing only progestogen, namely depot medroxyprogesterone acetate (DMPA) and norethisterone oenanthate (NET-EN), for the risks and reasons of their discontinuation and for their clinical effe
This review did not find strong evidence to demonstrate the effect of traditional Chinese herbal products in the treatment of stable angina
This review examines strategies to enable the continued use of the antibiotic cotrimoxazole in patients with HIV/AIDS to treat or prevent opportunistic infections in patients who previously experienced hypersensitivity to this drug.
This review examines the net impact of providing written action plans to children with asthma and their parents
This review is no longer appropriate for update as liquid based cytology has superceded smear technology.
This review is not appropriate for update since radiotherapy is now routinely combined with cisplatin and there have been no further studies using hydroxyurea.
This review searched for trials of women followed up after their first treatment for cervical cancer to find out the best approach to this care. 
This systematic review focuses on long-term outcome of laparoscopic versus open surgery for colorectal cancer, including long-term complications and cancer outcome.
This systematic review is on comparative effectiveness of different therapies used in short term management of gastro-oesophageal reflux disease (GORD)
Thoracic endoscopic stent graft versus open surgery for thoracic aneurysm
Thoracic epidural anaesthesia combined with general anaesthesia versus general anaesthesia alone for one-lung ventilation
Three dimensional imaging (3D) compared with two dimensional (2D) imaging for key hole removal of gallbladder
Three versus two treatments for H pylori infection
Three-drug versus two-drug induction therapy regimens for patients with transplant-eligible multiple myeloma
Thrombolysis for cerebral vein and dural sinus thrombosis
Thrombolysis for treatment of acute deep vein thrombosis
Thrombolytic agents for arterial and venous thromboses in neonates
Thrombophilia testing for the prevention of recurrent venous thromboembolism
Thrombopoietin mimetics for patients with myelodysplastic syndromes
Thrombopoietin receptor agonists for prevention and treatment of chemotherapy-induced thrombocytopenia in patients with solid tumours
Thumb-in-palm surgery appears to lead to modest improvement in hand function and quality of life in people with cerebral palsy.
Thymic peptides for treatment of cancer patients in addition to chemotherapy or radiotherapy, or both
Thymosin alpha1 for chronic hepatitis B
Thyroid hormone replacement for subclinical hypothyroidism
Thyroid hormone supplementation for the prevention of morbidity and mortality in infants undergoing cardiac surgery
Thyroid hormone therapy or minimally invasive treatments for benign thyroid nodules
Thyroid hormones for acute kidney injury
Thyroid hormones for preventing neurodevelopmental impairment in preterm infants
Thyroid surgery for Graves' disease and Graves' opthalmopathy
Thyrotropin-releasing hormone added to corticosteroids for women at risk of preterm birth for preventing neonatal respiratory disease
Thyroxine replacement therapy for subfertile women with autoimmune thyroid disease or mildly underactive thyroid
Tiagabine add-on therapy for drug-resistant focal epilepsy
Tiagabine in the maintenance treatment of bipolar disorder
Tiagabine to treat acute affective episodes in bipolar disorder
Tianma Gouteng Yin Formula for primary hypertension
Ticlopidine plus aspirin is better than oral anticoagulants alone for reducing the risk of revascularization, non-fatal myocardial infarction and bleeding following stenting of coronary arteries
Tidal versus other forms of peritoneal dialysis for patients with acute kidney injury
Tight control of mild-to-moderate high blood pressure for pregnant women with pre-existing or gestational hypertension (without protein in the urine) to improve health outcomes 
Time course for blood pressure lowering of alpha blockers
Time course for blood pressure lowering of angiotensin receptor blockers
Time course for blood pressure lowering of angiotensin-converting-enzyme inhibitors
Time course for blood pressure lowering of beta blockers with partial agonist activity
Time course for blood pressure lowering of beta one selective blockers
Time course for blood pressure lowering of dual alpha and beta blockers
Time course for blood pressure lowering of thiazides
Time effects of blood pressure lowering drugs for the treatment of high blood pressure
Time magazine cites Cochrane evidence in a story on lowering blood pressure
Time spent in rehabilitation and effect on measures of activity after stroke
Time to publication for results of clinical trials
Time-lapse systems for embryo incubation and embryo assessment for couples undergoing in vitro fertilisation and intracytoplasmic sperm injection
Time-limited home-care reablement services (up to 12 weeks) for supporting older adults to live independently
Timed intercourse for couples with subfertility
Timed voiding for the management of urinary incontinence in adults
Timing of antiretroviral therapy initiation in HIV-positive people with cryptococcal meningitis
Timing of initiation of renal replacement therapy for acute kidney injury
Timing of surgery for aneurysmal subarachnoid haemorrhage
Timing of surgery for premenopausal women with breast cancer
Timing of tracheostomy for critically ill patients who are predicted to be on long-term artificial respiration
Timing of treatment for people with recent symptoms from neck artery narrowing
Tinnitus Retraining Therapy (TRT) for tinnitus
Tiopronin for chronic hepatitis B
Tiotropium for managing COPD

Pages