Cognitive behavioural therapy for anxiety disorders in children and adolescents

  • To carry out a meta-analysis of identified studies to determine whether CBT leads to remission of 1) the primary child/adolescent anxiety disorder and 2) all anxiety diagnoses, and/or 3) a clinically significant reduction in anxiety symptoms in comparison with passive (waiting list) controls, active controls, treatment as usual, or medication.
  • To determine the comparative efficacy of CBT alone, and the combination of CBT and medication, versus drug placebo.
  • To determine whether post-treatment gains of CBT are maintained at longer-term follow-up.
  • To describe the age range of participants included in CBT trials in order to determine the age of the youngest participants.
  • To determine whether CBT for anxiety leads to a clinically significant reduction in depressive symptoms, and/or improvements in global functioning.
  • To carry out subgroup analyses of different types of CBT according to 1) amount of therapist contact time; and 2) delivery format (child-focused individual, group, and with/without family involvement, and parent-delivered).
  • To carry out a subgroup analysis of CBT for children and adolescents with ASD and for children and adolescents with intellectual impairments.

This is a protocol.