How effective are non-drug treatments used to prevent attacks of vestibular migraine? |
How effective are physical activity and education for chronic musculoskeletal pain in children and adolescents? |
How effective are strategies to help patients and their families secure emergency medical care when a health condition becomes life-threatening? |
How effective are strategies to improve the way health and social care professional groups work together? |
How effective are supervised exercise programmes compared to supervised walking programmes for treating intermittent claudication? |
How effective are the psychological interventions used for treating the consequences of sexual abuse in children and adolescents |
How effective are urinary catheter washout solutions? |
How effective are visual cycle modulators (a type of medicine) for preventing and treating geographic atrophy (a degenerative eye condition)? |
How effective is aripiprazole for calming people who are aggressive or agitated due to psychosis? |
How effective is pelvic floor muscle training undertaken during pregnancy or after birth for preventing or treating incontinence? |
How effective is radiotherapy for treating wet age-related macular degeneration (AMD) (a degenerative eye condition)? |
How effective is screening for COVID-19? |
How effects on health equity are assessed in systematic reviews of effectiveness |
How good are financial incentives in changing health care? |
How good are ultrasound, CT, MRI, and PET-CT for identifying spread of disease in the body among people with melanoma? |
How health equity is reported and analyzed in randomized trials |
How helpful to recovery and healing are support and psychological interventions after exposure to sexual violence and abuse? |
How long do clinical trials take to publish their results? |
How long do clinical trials take to publish their results? |
How much is enough: two new priority review updates on radiotherapy for breast cancer |
How often should dressings on central venous access devices (CVADs) be changed to reduce catheter-related infection? |
How often should you see your dentist for a check-up? |
How renin inhibitors (RIs) compare with angiotensin converting enzyme (ACE) inhibitors for treating hypertension |
How should we give taxane as a single chemotherapy agent to women with relapsed epithelial ovarian cancer? |
How similar are estimates of treatment effectiveness derived from randomised controlled trials and observational studies? |
How successful are healthy eating programmes in preschools, kindergartens and childcare settings? |
How successful are healthy eating programmes in preschools, kindergartens and childcare settings? |
How successful are healthy eating programmes in preschools, kindergartens and childcare settings? |
How systematic reviewers can bring attention to fraudulent studies, writes Lisa Bero in The Conversation US |
How to communicate scientific uncertainty: A Lifeology and Cochrane collaboration |
How to talk about vaccines when you’re not an expert: a Lifeology and Cochrane collaboration |
How useful is it to deliver asthma education to children, or their caregivers, or both, in the home? |
How useful is ultrasound for diagnosing giant cell arteritis? |
How well do Cesarian or vaginal delivery of babies prevent anal incontinence? |
How well do point-of-care tests detect Schistosoma infections in people living inendemic areas? |
How well do tools predict what happens with adults with newly-diagnosed chronic lymphocytic leukaemia (CLL) over time? |
How well does botulinum toxin (type A; often called ‘Botox’) treat wrinkles on the face? |
HOW WELL DOES CALCIUM SUPPLEMENTS WORK TO PREVENT BONE LOSS IN WOMEN AFTER MENOPAUSE? |
How well does pentoxifylline treat intermittent claudication? |
How well does rufinamide treat drug-resistant epilepsy when given with another antiepileptic medicine? |
HPV vaccination to prevent cancer and pre-cancerous changes of the cervix |
Huangqi preparations for unstable angina |
Human albumin for hypotension in haemodialysis patients |
Human albumin infusion for treating oedema in people with nephrotic syndrome |
Human chorionic gonadotrophin (hCG) priming in in vitro maturation (IVM) |
Human chorionic gonadotrophin for recurrent miscarriage |
Human chorionic gonadotrophin for threatened miscarriage |
Human chorionic gonadotrophin hormone for preventing recurrent miscarriage |
Human growth hormone and glutamine for patients with short bowel syndrome |
Human growth hormone for treating burns and skin graft donor sites |
Human insulin less temperature-sensitive than previously thought |
Human menopausal gonadotropin versus recombinant follicle stimulation hormone for ovarian stimulation in assisted reproductive cycles |
Human milk-derived fortifier in preterm infants fed with all breast milk |
Human papillomavirus (HPV) self-sampling to encourage the uptake of cervical screening |
Human papillomavirus (HPV) test compared to the Papanicolaou (Pap) test to screen for cervical cancer |
Human papillomavirus (HPV) vaccination for the prevention of cervical cancer and other HPV-related diseases: a network meta-analysis |
Human papillomavirus (HPV) vaccine for individuals with HIV infection |
Human papillomavirus testing versus repeat cytology for triage of minor cytological cervical lesions |
Human parathyroid hormone for preventing and treating glucocorticoid-induced osteoporosis |
Human parathyroid hormone for the treatment of osteoporosis in post-menopausal women |
Human recombinant activated protein C for severe sepsis and septic shock in adult and paediatric patients |
Human stem cells for decompensated cirrhosis in adults |
Humanistic therapies versus other psychological therapies for depression |
Humanistic therapies versus treatment as usual for depression |
Humanitarian Evidence Week |
Humour-based interventions for people with schizophrenia |
Hundreds of Nordic clinical trials remain unpublished |
Hyaluronate for shoulder osteoarthritis |
Hyaluronate for temporomandibular joint disorders |
Hyaluronic acid and other non-surgical treatment options for ankle osteoarthritis |
Hyaluronic acid for chronic wound healing |
Hyaluronidase for cervical ripening and induction of labour |
Hybrid versus conventional open repair for aortic arch dissection |
Hybrid versus conventional open surgical repair for thoracic aortic arch aneurysms |
Hydralazine for pulmonary hypertension in low birth weight infants with chronic lung disease |
Hydralazine for treatment of high blood pressure |
Hydration for treatment of preterm labour |
Hydrocolloid dressings for donor sites of split thickness skin grafts |
Hydrocolloid dressings for healing venous leg ulcers |
Hydrocolloid dressings for treating pressure ulcers |
Hydrocolloid dressings to promote foot ulcer healing in people with diabetes when compared with other dressing types |
Hydrogel dressings for treating pressure ulcers |
Hydrogel dressings for venous leg ulcers |
Hydrogel dressings to promote diabetic foot ulcer healing |
Hydromorphone for acute and chronic pain |
Hydromorphone for neuropathic pain in adults |
Hydromorphone for the treatment of cancer pain |
Hydroxychloroquine for systemic lupus erythematosus in adults |
Hydroxyethyl starch (HES) versus other fluid therapies: effects on kidney function |
Hydroxymethylglutaryl-CoA reductase inhibitors (statins) for the treatment of sepsis |
Hydroxyurea (also known as hydroxycarbamide) for people with sickle cell disease |
Hydroxyurea (also known as hydroxycarbamide) for people with sickle cell disease |
Hydroxyurea (hydroxycarbamide) for treating people with transfusion-dependent beta-thalassaemia |
Hydroxyurea for reducing blood transfusion in non-transfusion dependent beta thalassaemias |
Hydroxyzine for generalised anxiety disorder |
Hyperbaric oxygen as an additional treatment for malignant otitis externa |
Hyperbaric oxygen for newborns with hypoxic ischaemic encephalopathy |
Hyperbaric oxygen for sudden hearing loss and tinnitus (ringing in the ears) of unknown cause |
Hyperbaric oxygen therapy for acute surgical and traumatic wounds |
Hyperbaric oxygen therapy for delayed onset muscle soreness and closed soft tissue injury |
Hyperbaric oxygen therapy for persistent post-concussion syndrome following mild traumatic brain injury |
Hyperbaric oxygen therapy for the treatment of the late effects of radiotherapy |
Hyperbaric oxygen therapy for treating chronic wounds |
Hyperbaric oxygen therapy for treating people with acute ischaemic stroke |
Hyperbaric oxygen therapy for vascular dementia |
Hyperbaric oxygen therapy, which involves people breathing pure oxygen in a specially designed chamber, for the treatment of multiple sclerosis |
Hyperfractionated or accelerated radiotherapy for head and neck cancer |
Hyperthermia seems to have an additional effect when added to radiotherapy in the treatment of advanced rectal cancer. |
Hypertonic saline (salt water with at least 3% salt) nebulised as a fine mist through a mask or mouthpiece for cystic fibrosis |
Hypnosis during pregnancy, childbirth, and the postnatal period for preventing postnatal depression |
Hypnosis for alleviation of anxiety in adults undergoing dental treatment |
Hypnosis for children undergoing dental treatment |
Hypnosis for induction of labour |
Hypnosis for pain management during labour and childbirth |
Hypnosis for preventing preterm labour |
Hypnosis for schizophrenia |
Hypnotherapy (treatment by hypnosis) for the treatment of irritable bowel syndrome |
Hypoallergenic formula milk versus cow's milk for prevention of wheeze and asthma in children with a family history of atopy |
Hypoglycaemic agents for pregnant women with polycystic ovarian syndrome |
Hypolipidemic and antihypertensive drugs for prevention of cardiovascular complications in patients with rheumatoid arthritis |
Hypomethylating agents for adult patients with acute myeloid leukaemia |
Hypomethylating agents for patients with myelodysplastic syndrome |
Hypothermia (body temperature cooling) for people with an injury to the brain |
Hysterectomy versus hysterectomy plus ovary removal for premenopausal women |
Hysterectomy with medical management for cervical cancer that has spread to nearby tissues only |
Hysteroscopy for treating suspected abnormalities of the cavity of the womb in women having difficulty becoming pregnant |
Iberogast (STW5) for functional dyspepsia |
Ibuprofen for pain relief after surgical removal of lower wisdom teeth |
Ibuprofen for prevention of patent ductus arteriosus in preterm and/or low birth weight infants |
Ibuprofen for the treatment of patent ductus arteriosus in preterm or low-birth-weight (or both) infants |
Ibuprofen versus paracetamol (acetaminophen) for pain relief after surgical removal of lower wisdom teeth |
Ibuprofen with or without an antiemetic for acute migraine headaches in adults |
Ibuprofen-like painkillers given before cutting the skin in surgery compared with given after cutting the skin in adults undergoing all types of surgery |
Idarubicin for treatment of newly diagnosed acute myeloid leukaemia |
Ideal length of treatment for Helicobacter pylori (H. pylori) eradication |
Idebenone for the treatment of Duchenne muscular dystrophy |
Identification (through screening) of children in the first four years of life for early treatment for otitis media with effusion (OME) |
Identification of nerves using an electrode compared with visual nerve identification for adults undergoing thyroid surgery |
Identifying carrier status for thalassaemia, sickle cell disease, cystic fibrosis, or Tay-Sachs disease in non-pregnant women and their partners |
Identifying the most clinically effective exercise prescription for people with intermittent claudication (MAXIMISE): a component network meta-analysis with concurrent cost-effectiveness analysis |
Idiotype vaccination for Non-Hodgkin lymphoma |
Ileostomy or colostomy for temporary decompression of colorectal anastomosis |
Illness management and recovery programme for people with severe mental illness |
Illustrating Cochrane evidence in a more gentle way: Interview with Jen Ma |
Iloperidone versus placebo for schizophrenia |
Iloprost and cisaprost for Raynaud's phenomenon in progressive systemic sclerosis |
Image-guided percutaneous renal core biopsy of small renal masses to diagnose renal cancer |
Image-guided surgery for brain tumours |
Image-guided surgery for brain tumours |
Image-guided versus blind glucocorticoid injection for shoulder pain |
Imaging guided surgery for brain tumours |
Imaging techniques for antenatal detection of morbidly adherent placenta |
Imaging tests for the non-invasive diagnosis of endometriosis |
Imaging with positron emission tomography (PET) during chemotherapy to predict outcome in adults with Hodgkin lymphoma |
Imaging-adapted therapy for individuals with Hodgkin lymphoma |
Imatinib for treating patients with chronic myelogeneous leukemia |
Imatinib mesylate for gastrointestinal stromal tumours (GISTs) |
Imipramine for neuropathic pain in adults |
Imiquimod for anogenital warts in non-immunocompromised adults |
Immediate antiepileptic drug treatment, versus placebo, deferred, or no treatment for first unprovoked seizure |
Immediate closure or delayed closure for treating traumatic wounds in the first 24 hours following injury |
Immediate or delayed birth for a preterm fetus with suspected compromise |
Immediate start of hormonal birth control |
Immediate versus delayed reconstruction following surgery for breast cancer |
Immersion in water in labour and birth |
Immobilisation and functional treatment for acute lateral ankle ligament injuries in adults |
Immobilisation versus early ankle movement for treating acute lateral ankle ligament injuries in adults |
Immune checkpoint inhibitors (anti PD-1 or anti PD-L1) plus platinum-etoposide versus platinum-etoposide alone for first-line treatment of extensive small cell lung cancer |
Immune checkpoint inhibitors (anti PD-1 or anti PD-L1) versus chemotherapy for second- or third-line treatment of metastatic non-small cell lung cancer |
Immune checkpoint inhibitors and chemotherapy versus chemotherapy for early triple-negative breast cancer |
Immune checkpoint inhibitors for advanced pancreatic cancer |
Immune checkpoint inhibitors for unresectable hepatocellular carcinoma |
Immune checkpoint inhibitors plus chemotherapy versus chemotherapy or immune checkpoint inhibitors for first- or second-line treatment of advanced gastric and gastro-esophageal junction cancer |
Immune checkpoint inhibitors plus chemotherapy versus chemotherapy or immunotherapy for first-line treatment of advanced non-small cell lung cancer: a generic protocol |
Immune system treatments other than corticosteroids, immunoglobulin and plasma exchange for CIDP |
Immune therapies for women with history of failed implantation undergoing IVF treatment |
Immune therapy for lumbosacral plexopathy (a condition that affects the network of nerves at the base of the spine) of unknown cause |
Immune tolerance induction to destroy inhibitors in people with haemophilia A or B |
Immune treatments for peripheral neuropathy caused by an IgM paraprotein antibody, which may bind to MAG, a protein on the myelin sheath of nerves |
Immunity in vulnerable groups after COVID-19 vaccination |
Immunoglobulin for alloimmune hemolytic disease in newborns |
Immunoglobulin for myasthenia gravis |
Immunoglobulin replacement to prevent infections in people with haematological malignancies and haematopoietic stem cell transplantation |
Immunoglobulin treatment for Kawasaki disease |
Immunoglobulins (human serum immune gamma globulins) seem effective for prevention of hepatitis A |
Immunomodulatory interventions (treatments that target the immune system) for focal epilepsy |
Immunomodulatory treatment for amyotrophic lateral sclerosis/motor neuron disease |
Immunonutrition as an adjuvant therapy for burns |
Immunonutrition for acute respiratory distress syndrome (ARDS) in adults |
Immunonutrition for patients undergoing surgery for head and neck cancer |
Immunostimulants to prevent acute respiratory tract infections in children |
Immunostimulating agents for the prevention of acute otitis media |
Immunosuppressants to prevent corneal graft rejection after penetrating keratoplasty |
Immunosuppressive agents for treating IgA nephropathy |
Immunosuppressive and cytotoxic therapy for pulmonary sarcoidosis |
Immunosuppressive and immunomodulatory therapies for idiopathic inflammatory myopathies |
Immunosuppressive T cell antibody induction therapy for liver transplant recipients |
Immunosuppressive therapy for treating of IgA nephropathy in children |
Immunosuppressive treatment for adults with idiopathic membranous nephropathy |
Immunosuppressive treatment for focal segmental glomerulosclerosis in adults |
Immunosuppressive treatment for people with proliferative lupus nephritis |
Immunotherapy by allergen injections for seasonal allergic rhinitis ('hay fever') |
Immunotherapy for advanced and recurrent malignant pleural mesothelioma |
Immunotherapy for advanced kidney cancer |
Immunotherapy for advanced kidney cancer |
Immunotherapy for intracranial metastatic melanoma |
Immunotherapy for non-small cell lung cancer in the elderly population: a generic protocol |
Immunotherapy for preventing allergic reactions to insect stings |
Immunotherapy for recurrent miscarriage |
Immunotherapy versus chemotherapy for people with advanced non-small cell lung cancer who have not been not previously been treated |
Immunotherapy versus chemotherapy for treating inoperable or metastatic bladder cancer |
Impact of computed tomography (CT) on lung cancer screening |
Impact of diagnostic strategies for tuberculosis using lateral flow urine lipoarabinomannan test in people living with HIV |
Impact of entertainment media smoking on adolescent smoking behaviours |
Impact of epithelial ovarian cancer screening on patient-relevant outcomes in average-risk postmenopausal women |
Impact of exposure to alcohol marketing and subsequent drinking patterns among youth and young adults |
Impact of food fortification with multiple micronutrients on health |
Impact of food fortified with vitamin D and Calcium on health outcomes |
Impact of long-term opioid use for chronic non-cancer pain on misuse, abuse or addiction, overdose, falls and fractures |
Impact of morphine, fentanyl, oxycodone or codeine on patient consciousness, appetite and thirst when used to treat cancer pain |
Impact of offering incentives in exchange for attending prenatal care visits on maternal and neonatal health outcomes |
Impact of ovarian preservation on survival for women with endometrial carcinoma |
Impact of shared scientific or ethical review of multicentre clinical research on the quality of clinical research and the clinical research process |
Implantable cardiac monitors compared with conventional methods for the detection of atrial high-rate episodes in individuals with embolic stroke of undetermined source |
Implantable cardioverter defibrillators versus medical therapy for people with inherited heart rhythm abnormalities |
Implantable device monitoring versus usual care for managing individuals with heart failure |
Implantable loop recorder versus conventional diagnostic assessment for people with unexplained recurrent fainting |
Implantable miniature telescope for vision loss due to end-stage age-related macular degeneration |
Implants in knee replacement surgery for patients with osteoarthritis and rheumatoid arthritis |
Implementation of treatment guidelines in mental health care |
Implementation strategies for health systems in low-income countries |
Important Cochrane Links |
Important Update: Colloquium Cancelled |
Improved learning with Cochrane Training website |
Improving access to food in low- and middle-income countries |
Improving birth control use with programs based on theory |
Improving healthcare professionals' reporting of adverse drug reactions and medication errors |
Improving healthcare workers' use of Standard Precautions to decrease infection in healthcare settings |
Improving how antibiotics are prescribed by physicians working in the community. |
Improving how physicians working in hospital settings prescribe antibiotics |
Improving maternal, newborn and women's reproductive health in crisis settings |
Improving outcomes for people with multiple chronic conditions |
Improving palliative care for older people in care homes |
Improving return to work in adults suffering from symptoms of distress |
Improving surgical practice - a systematic review of effective education strategies to improve surgical technical skills in operative procedures |
Improving the implementation of health-promoting policies and practices in workplaces |
Improving the implementation of healthy eating, physical activity and obesity prevention policies, practices or programmes in childcare services |
Improving the implementation of school-based policies and practices to improve student health |
Improving the implementation of school-based policies and practices to improve student health |
Improving the outcome of people with primary brain tumours and their carers using early palliative interventions |