To evaluate third and fourth generation cephalosporins in the treatment of enteric fever in children and adults compared with other antibiotics. The primary objectives are:

• to identify whether the drugs under scrutiny are clinically effective
• which is the optimal agent and at what dose
• what is the most appropriate route of administration
• what is the ideal treatment duration

Therefore, we will perform within-class comparisons and an assessment of third and fourth generation cephalosporin treatment duration.