Cochrane Handbook for Systematic Reviews of Interventions (current version)

Version 6.5, 2024

Senior Editors: Julian Higgins¹, James Thomas²
Associate Editors: Jacqueline Chandler³, Miranda Cumpston^4,5, Tianjing Li⁶, Matthew Page⁴, Vivian Welch⁷

Part 1: About Cochrane Reviews I.     Introduction II.    Planning a Cochrane Review III.   Reporting the review III.S1 Supplementary material: Considerations and recommendations for figures in Cochrane reviews III.S2 Supplementary material: Guidance for writing a Cochrane Plain language summary IV.   Updating the review V.    Overviews of Reviews Part 2: Core methods Starting a review Determining the scope and questions Inclusion criteria & grouping for synthesis Searching & selecting studies 4.S1 Supplementary material: Technical supplement 4.S2 Supplementary material: Appendix of resources Collecting data Effect measures Bias and conflicts of interest Risk of bias in randomized trials Preparing for synthesis Meta-analyses Network meta-analyses Synthesis using other methods Bias due to missing results ‘Summary of findings’ tables & GRADE Interpreting results

Part 3: Specific perspectives in reviews Equity Intervention complexity Patient-reported outcomes Adverse effects Economic evidence 20.S Technical Supplement to Chapter 20: Integrated full systematic re Living systematic reviews Please note, users should visit the Cochrane and Campbell Handbook for Qualitative Evidence Synthesis for methods on qualitative evidence synthesis. The Handbook chapter on qualitative evidence synthesis (Chapter 21) is no longer available.  Part 4: Other topics Prospective approaches Variants on randomized trials Including non-randomized studies Risk of bias in non-randomized studies Individual participant data

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¹ University of Bristol, UK
² EPPI-Centre, UCL Social Research Institute, University College London, UK
³ Wessex Academic Health Science Network, UK 
⁴ School of Public Health and Preventive Medicine, Monash University, Australia
⁵ Cochrane Public Health; School of Medicine and Public Health, University of Newcastle, Australia
⁶ Department of Ophthalmology, School of Medicine & Department of Epidemiology, School of Public Health, University of Colorado Anschutz Medical Campus USA; Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, USA
⁷ The Campbell Collaboration; Bruyère Research Institute, Ottawa, Canada; School of Epidemiology and Public Health, University of Ottawa, Canada. 

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