Electroconvulsive therapy for treatment-resistant schizophrenia

Our primary objective is to assess the effects (benefits and harms) of ECT for people with treatment-resistant schizophrenia.

Our secondary objectives are to determine whether ECT produces a differential response in people:

  • who are treated with unilateral compared to bilateral ECT;
  • who have had a long course of ECT (more than 12 sessions) or short course of ECT;
  • who are given continuation or maintenance ECT;
  • who are diagnosed with well defined treatment resistant schizophrenia as opposed to less rigorously defined treatment-resistant schizophrenia (who would be expected to have a greater affective component to their illness).

This is a protocol.