| Drugs improving insulin resistance for non-alcoholic fatty liver disease and/or non-alcoholic steatohepatitis |
| Drugs in overactive bladder syndrome |
| Drugs other than those used for epilepsy for treating trigeminal neuralgia |
| Drugs targeting PI3K/AKT/mTOR pathway for locally-advanced, metastatic or recurrent endometrial cancer |
| Drugs that aim to prevent the loss of protein or albumin through urine in people with sickle cell disease |
| Drugs that aim to reduce the loss of water from red blood cells in people with sickle cell disease |
| Drugs that aim to relieve clinical symptoms of tuberous sclerosis complex |
| Drugs that prevent oral bleeding in people using oral anticoagulants undergoing minor oral surgery or dental extractions |
| Drugs that prevent oral bleeding in people with haemophilia or Von Willebrand disease undergoing minor oral surgery or dental extractions |
| Drugs that suppress or modify the immune system for dermatomyositis and polymyositis |
| Drugs that target abnormal growth protein in high-grade, aggressive brain tumours |
| Drugs that target blood vessels in malignant brain tumours |
| Drugs to break down blood clots for people with sudden onset peripheral arterial occlusion |
| Drugs to control the movement of salt in the lungs of people with cystic fibrosis |
| Drugs to dissolve pulmonary embolism (blood clot in the lungs) |
| Drugs to help end amphetamine dependence are not very helpful, and more research is needed. |
| Drugs to help reduce anxiety in people nearing the end of life due to illness |
| Drugs to improve blood flow for people who have poor blood circulation in the veins of their legs |
| Drugs to improve placental function in pregnant women carrying babies with poor growth |
| Drugs to manage pain and sedation during cooling in newborns following poor brain oxygenation at birth (hypoxic-ischaemic encephalopathy) |
| Drugs to prevent clots after bleeding in the brain |
| Drugs to prevent heart damage in cancer patients receiving anthracyclines |
| Drugs to prevent malaria in HIV-positive pregnant women |
| Drugs to prevent malaria in HIV-positive pregnant women |
| Drugs to prevent nausea and vomiting in children and young people undergoing chemotherapy |
| Drugs to prevent the re-occurrence of narrowing of blood vessels in peripheral arterial disease after the blood vessels have been surgically widened |
| Drugs to reduce bleeding and transfusion in adults undergoing cardiac surgery: a systematic review and network meta-analysis |
| Drugs to relieve pain for children with acute middle ear infection |
| Drugs to suppress the immune system after lung transplantation in people with cystic fibrosis |
| Drugs to treat acute respiratory distress syndrome in adults |
| Drugs to treat fibroids |
| Drugs to treat phantom limb pain in people with missing limbs |
| Drugs used as add-on therapy to heart procedure following heart attack |
| Drugs used to lower blood pressure do not reduce sudden death |
| Drugs used to treat the symptoms of patellofemoral syndrome have little evidence base |
| Dual antibiotics for bronchiectasis |
| Dual combination therapy versus long-acting bronchodilators alone for chronic obstructive pulmonary disease (COPD): a systematic review and network meta-analysis |
| Dual task training for improving balance and gait in people with stroke |
| Duloxetine can improve the quality of life of patients with stress urinary incontinence, long-term effects of the treatment are unclear. |
| Duloxetine for generalised anxiety disorder (GAD) |
| Duloxetine for treating painful neuropathy, chronic pain or fibromyalgia |
| Duloxetine versus other antidepressive agents for depression |
| Duodenum-preserving pancreatic resection versus pancreaticoduodenectomy for chronic pancreatitis |
| Duplex ultrasound for the detection of stenosis after peripheral arterial bypass grafting using autologous vein |
| Duplex ultrasound for the diagnosis of symptomatic deep vein thrombosis in the lower limb |
| Duration of 5FU based chemotherapy in adjuvant setting for colorectal cancer should not exceed 6 months. |
| Duration of antibacterial treatment for uncomplicated urinary tract infection in women |
| Duration of antibiotic treatment for foot osteomyelitis in people with diabetes |
| Duration of chemotherapy for metastatic breast cancer |
| Duration of therapy for tuberculosis in patients infected with Human Immunodeficiency Virus |
| Duration of treatment for asymptomatic bacteriuria during pregnancy |
| Dying Matters Awareness Week |
| Dynamic exercise programs (aerobic capacity and/or muscle strength training) in patients with rheumatoid arthritis |
| Dynamic exercise therapy for rheumatoid arthritis is effective in increasing aerobic capacity, muscle strength and joint mobility and does not increase disease activity, joint damage or pain. |
| Dysphagia occurs frequently in Parkinson's disease although patients themselves may be unaware of swallowing difficulties. Speech and language therapists in conjunction with nurses and dietiticians use techniques that aim to improve swallowing and reduce |
| E-cigarettes, varenicline and cytisine are the most effective stop-smoking aids, analysis of over 150,000 smokers reveals |
| E-health interventions for anxiety and depression in children and adolescents with long-term physical conditions |
| Ear drops for the removal of ear wax |
| Earlier compared to later addition of human milk fortifier to human milk to promote growth in preterm infants |
| Early (less than 30 days after the start of chemotherapy) or late (more than 30 days after the start of chemotherapy) chest radiotherapy for patients suffering from limited small cell lung cancer |
| Early (started within six days) systemic postnatal corticosteroids for preventing bronchopulmonary dysplasia in preterm infants |
| Early additional food and fluids for healthy breastfed full-term infants |
| Early administration of inhaled corticosteroids for preventing chronic lung disease in very low birth weight preterm neonates |
| Early amniocentesis versus transabdominal chorion villus sampling for prenatal diagnosis |
| Early amniotomy and early oxytocin for delay in first stage spontaneous labour compared with routine care |
| Early and late adverse effects on the kidney after treatment for childhood cancer |
| Early Bird Colloquium Registration Deadline: July 25 |
| Early bird registration and stipends now open for the Global Evidence Summit |
| Early bird registration now open for Cochrane Colloquium Santiago |
| Early bird registration now open for the Global Evidence Summit |
| Early birth compared with waiting for birth in babies who are thought to be coping poorly towards the end of pregnancy |
| Early birth for babies with gastroschisis |
| Early combination therapy with levodopa and dopamine agonist for preventing motor fluctuations in Parkinson's disease |
| Early compared with delayed oral fluids and food after caesarean section |
| Early discharge of preterm infants from hospital |
| Early elbow movement compared to delayed elbow movement after a broken elbow in adults |
| Early emergency department treatment of acute asthma with systemic corticosteroids |
| Early erythropoiesis-stimulating agents in preterm or low birth weight infants |
| Early excision and grafting for burns |
| Early full enteral feeds for preterm or low birth weight infants |
| Early intensive behavioral intervention (EIBI) for increasing functional behaviors and skills in young children with autism spectrum disorders (ASD) |
| Early intervention (movement or active exercise) for critically ill adults in the intensive care unit |
| Early intervention delivered by parents for young children with autism spectrum disorders |
| Early intervention delivered by parents to young children with autism spectrum disorder |
| Early intervention for high risk smoldering multiple myeloma (SMM) |
| Early Intervention for psychosis |
| Early interventions for people at risk of developing psychosis |
| Early intravenous nutrition for the prevention of neonatal jaundice |
| Early introduction of lipids to parenterally-fed preterm infants |
| Early laparoscopy versus observation for patients with acute abdominal pain |
| Early lens extraction compared to standard treatment in acute primary angle closure |
| Early light reduction for preventing retinopathy of prematurity in very low birth weight infants |
| Early mobilization after skin graft for burn injury in adults |
| Early nasal intermittent positive pressure ventilation (NIPPV) versus early nasal continuous positive airway pressure (NCPAP) for preterm infants |
| Early nasal intermittent positive pressure ventilation (NIPPV) versus early nasal continuous positive airway pressure (NCPAP) for preterm infants |
| Early nutritional therapy for malnourished or nutritionally at-risk adult medical inpatients |
| Early or delayed removal of gallbladder by key-hole surgery after a sudden episode of gallstone-related pancreatitis |
| Early or delayed surgical removal of the appendix: which works better to treat an appendiceal mass (lump on the appendix)? |
| Early palliative care for adults with advanced cancer |
| Early planned removal of umbilical venous catheters to prevent infection in newborn infants |
| Early planned removal versus expectant management of peripherally inserted central catheters to prevent infection in newborn infants |
| Early postnatal discharge from hospital for healthy mothers and term infants |
| Early pregnancy screening for identification of undiagnosed pre-existing diabetes to improve maternal and infant health |
| Early psychological interventions to treat acute traumatic stress symptoms |
| Early referral to a specialist doctor for people with kidney disease |
| Early registration for Cochrane Colloquium Edinburgh extended until Friday 22 June |
| Early removal versus expectant management of central venous catheters in newborn infants with bloodstream infection |
| Early skin-to-skin contact for mothers and their healthy newborn infants |
| Early surfactant administration with brief ventilation vs. selective surfactant and continued mechanical ventilation for preterm infants with or at risk for respiratory distress syndrome |
| Early surgical treatment versus observational management for cervical intraepithelial neoplasia 2 (CIN2) |
| Early treatment for early stage multiple myeloma may slow the disease progression but does not appear to improve survival |
| Early treatment versus expectant management of symptomatic patent ductus arteriosus in preterm infants |
| Early treatment with blood-thinning drugs for people who have had a stroke |
| Early trophic feeding versus enteral fasting for very preterm or very low birth weight infants |
| Early use of inhaled corticosteroids in the emergency department treatment of acute asthma |
| Early versus delayed anticoagulation treatment for people with non-valvular atrial fibrillation-related acute ischaemic stroke |
| Early versus delayed dressing removal for people with surgical wounds |
| Early versus delayed erythropoietin for the anaemia of end-stage kidney disease |
| Early versus delayed feeding through a tube for critically ill adults in intensive care, with or without extra nutrition into a vein |
| Early versus delayed initiation of continuous positive airway pressure (CPAP) for respiratory distress in preterm infants |
| Early versus delayed laparoscopic cholecystectomy for people with acute cholecystitis |
| Early versus delayed laparoscopic cholecystectomy for uncomplicated biliary colic |
| Early versus delayed mobilisation to prevent further bleeding after spontaneous bleeding on the surface of the brain |
| Early versus delayed selective surfactant treatment for neonatal respiratory distress syndrome |
| Early versus delayed timing of vitrectomy after open-globe injury |
| Early versus late antiepileptic drug withdrawal for people with epilepsy in remission |
| Early versus late discontinuation of oxygen in preterm or low birth weight infants |
| Early versus late erythropoietin for preventing red blood cell transfusion in preterm and/or low birth weight infants |
| Early versus late hormonal treatment for advanced prostate cancer |
| Early versus late initiation of epidural analgesia for labour |
| Early versus late intravenous nutrition in critically ill term and late preterm babies |
| Early versus late surgical start times for on-pump cardiac surgery |
| Early versus late tracheostomy in people with multiple trauma |
| Early versus late ureteric stent removal after kidney transplantation |
| Early versus late urethral catheter removal after kidney transplantation |
| Early volume expansion for prevention of morbidity and mortality in very preterm infants |
| Early volume expansion versus inotrope for prevention of morbidity and mortality in very preterm infants |
| Easier access to emergency contraception to help women prevent unwanted pregnancy |
| Easing of bone pain caused by metastatic cancer: single versus multifraction radiotherapy |
| Eating and drinking in labour |
| Eating nuts to prevent cardiovascular disease |
| Echinacea for preventing and treating the common cold |
| Economic incentives to enhance safety behaviour in workers for preventing occupational injuries |
| Economic interventions for prevention of HIV risk and HIV infection |
| Eculizumab for treating patients with paroxysmal nocturnal hemoglobinuria |
| Edaravone for acute intracerebral haemorrhage |
| Edaravone for acute ischaemic stroke |
| Edaravone for traumatic brain injury |
| Edinburgh Colloquium 2018: Round-Up |
| Edinburgh Colloquium schedule sign-up and app are now launched |
| Editor in Chief discusses the journey to the new Cochrane Library |
| Editor in Chief to present on panel about COVID-19 transmission on September 18 |
| Editorial peer review for improving the quality of reports of biomedical studies |
| Editorial: Achieving sustainable healthcare through deprescribing |
| Educating healthcare staff to prevent pressure ulcers |
| Educating people with diabetes about foot care to help reduce foot ulcers and amputations |
| Education about family planning for women who have just given birth |
| Education and training for preventing sharps injuries and splash exposures in healthcare workers |
| Education and training interventions for healthcare workers to prevent sexual harassment |
| Education for nursing home staff and/or residents to improve residents' oral health |
| Education for people with coronary heart disease |
| Education for the management of cancer-related fatigue |
| Education interventions for adults who attend the emergency room for acute asthma |
| Education of family members to support weaning to solids and nutrition in infants born preterm |
| Education of health professionals for preventing diabetic foot ulceration |
| Education programmes for patients with inflammatory bowel disease (IBD) |
| Educational and behavioural interventions to increase the time in the therapeutic range for patients with atrial fibrillation on anticoagulant therapy |
| Educational benefits of deworming children questioned by re-analysis of flagship study |
| Educational games for mental health professionals |
| Educational games to improve health care professional practice and care for patients |
| Educational interventions for asthma in children |
| Educational interventions for health professionals managing people with COPD in primary care |
| Educational interventions for improving complementary feeding practices |
| Educational interventions for improving the communication skills of general practice trainees in the clinical consultation |
| Educational interventions for improving the skills of medical practitioners to detect, diagnose, and manage people with cognitive impairment and dementia |
| Educational interventions for preventing eye injuries |
| Educational interventions for promoting stroke literacy in the general public |
| Educational outreach visits to change health care professional care for patients |
| Educational programmes for primary prevention of skin cancer |
| Educational programs and training to prevent lead uptake in workers exposed to lead |
| EEG for children with complex febrile seizures |
| EEG neurofeedback for executive functions in children with neurodevelopmental challenges |
| EEG neurofeedback for inattention in children with Attention Deficit Hyperactivity Disorder (ADHD) |
| Effect of antihypertensive drugs on mortality, morbidity and blood pressure in blacks |
| Effect of applying cricoid pressure during rapid sequence induction of general anaesthesia |
| Effect of atorvastatin on cholesterol |
| Effect of birth control pills and patches on weight |
| Effect of birth control pills on acne in women |
| Effect of cocoa on blood pressure |
| Effect of cutting down on the saturated fat we eat on our risk of heart disease |
| Effect of cutting down the amount of fat on bodyweight in children |
| Effect of cutting down the fat we eat on body weight |
| Effect of cutting down the fat we eat on body weight |
| Effect of decision-support tools on mobile phones on primary health care |
| Effect of drugs to treat intestinal worms from contaminated soil in pregnant women |
| Effect of exchange transfusion on mortality in neonates with septicemia |
| Effect of high feedback versus low feedback of prenatal ultrasound on maternal anxiety and health behaviour in pregnancy |
| Effect of immunotherapy on the prognosis for stages I to III non-small cell lung cancer treated with surgery or radiotherapy with curative intent |
| Effect of lipid-based nutrient supplementation on infants and young children |
| Effect of methylphenidate for inattentiveness, impulsivity and/or hyperactivity in children aged 6 to 18 years with autistic spectrum disorder |
| Effect of molecular-targeted therapy on the progress and survival of people in the late stages of stomach cancer |
| Effect of natural sweetener Xylitol in preventing tooth decay still unproven |
| Effect of nonsteroidal anti-inflammatory medicines on kidney function in patients with normal kidney function undergoing surgery |
| Effect of partograph use on outcomes for women in spontaneous labour at term |
| Effect of phosphodiesterase 5 inhibitors on blood pressure |
| Effect of pre-exchange albumin infusion on neonatal hyperbilirubinaemia and long-term developmental outcomes |
| Effect of preventive interventions for malaria on HIV-1 disease progression in non-pregnant adults |
| Effect of restricted pacifier use on duration of breastfeeding in full-term infants |
| Effect of return-to-work coordination programmes for workers on sick leave |
| Effect of taurine supplementation on growth and development in preterm or low birth weight infants |
| Effect of the long-term use of proton pump inhibitors on the rate of pre-cancerous lesions in the stomach |
| Effect of the treatment of Type 2 diabetes mellitus on the development of cognitive impairment and dementia |
| Effect of the vaginal sponge and the diaphragm in preventing pregnancy |
| Effect of timing of umbilical cord clamping of term infants on mother and baby outcomes |
| Effectiveness and cost-effectiveness of home-based palliative care services for adults with advanced illness and their caregivers |
| Effectiveness and cost-effectiveness of hospital-based specialist palliative care (HSPC) for adults with advanced illness and their unpaid caregivers |
| Effectiveness and safety of devices designed to close femoral artery puncture sites |
| Effectiveness and safety of first-line tenofovir + emtricitabine + efavirenz for patients with HIV |
| Effectiveness and safety of HIV post-exposure prophylaxis after sexual, injecting-drug-use or other non-occupational exposure. |
| Effectiveness and safety of inhalers containing the drug aclidinium bromide for managing patients with stable COPD |
| Effectiveness and safety of switching IBD patients from the originator to the biosimilar infliximab |
| Effectiveness and safety of topiramate for drug dependents |
| Effectiveness and safety of two types of tools used in LASIK (a type of refractive surgery) for nearsightedness |
| Effectiveness of angioplasty compared with stenting in atherosclerotic disease of the iliac arteries |
| Effectiveness of anticholinergic drugs for treating people with overactive bladder syndrome |
| Effectiveness of brief alcohol interventions in primary care populations |
| Effectiveness of Copper-containing intra-uterine devices (coil) |
| Effectiveness of creatine analogues in cardiac disease |
| Effectiveness of dental auxiliaries performing clinical tasks traditionally provided by a dentist |
| Effectiveness of dressings and other devices that are used to keep a peripheral venous catheter in place |
| Effectiveness of EFV compared to NVP in the suppression of HIV infection when used as part of initial three-drug combination |
| Effectiveness of equivalent schedules of full-dose inactivated poliovirus vaccine injected into muscle compared to a smaller dose injected into skin |
| Effectiveness of intermediate care in nursing-led in-patient units |
| Effectiveness of knowledge translation interventions to improve cancer pain management |
| Effectiveness of paracetamol as a treatment for acute or chronic pain conditions |
| Effectiveness of SARS-CoV-2 testing strategies |
| Effectiveness of staffing models in residential/subacute/extended aged-care settings |
| Effectiveness of surgery for people with leg or back pain due to symptomatic spinal stenosis |
| Effectiveness of tools developed and disseminated by guideline producers to improve uptake of their guidelines |
| Effectiveness of Transcutaneous Electrical Nerve Stimulation (TENS) alone in the management of chronic pain |
| Effectiverness of epidural, subarachnoid and intracerebroventricular opioid drugs to treat patients with pain due to cancer |
| Effects and safety of long-term use of colchicine on heart disease |
| Effects of a gluten-reduced or gluten-free diet for the primary prevention of cardiovascular disease |
| Effects of antiepileptic drugs for the primary and secondary prevention of seizures after stroke |
| Effects of antihistamines on eczema |
| Effects of blood pressure lowering drugs given in the first 24 hours of heart attack or stroke |
| Effects of changing practitioner empathy and patient expectations in healthcare consultations |
| Effects of clinical pathways in hospitals on patient outcomes, length of hospital stay, hospital costs and charges, and adherence to recommended practice. |
| Effects of computerised clinical decision support systems (CDSS) on nursing and allied health professional performance and patient outcomes |
| Effects of daily oral iron supplementation during pregnancy |
