| Does monitoring oxygen level with a pulse oximeter during and after surgery improve patient outcomes? |
| Does more support increase success amongst people using medications to quit smoking? |
| Does motivational interviewing help people reduce their use of alcohol, drugs, or both? |
| Does motivational interviewing help people reduce their use of alcohol, drugs, or both? |
| Does motivational interviewing help people to quit smoking? |
| Does music-based therapy help people with dementia? |
| Does Nicobrevin help people to stop smoking |
| Does non-invasive brain stimulation or language training help people with primary progressive aphasia? |
| Does oestrogen therapy help to treat pelvic organ prolapse in postmenopausal women? |
| Does perineal hyaluronidase injection during the second stage of labour reduce genital damage in a woman giving birth? |
| Does perioperative blood transfusion affect the recurrence rate of potentially curable operations for colorectal cancer? |
| Does personalised advice via computer or mobile devices reduce heavy drinking? |
| Does physical exercise have beneficial or harmful effects in cirrhosis? |
| Does physiotherapy improve pain and disability in adults with complex regional pain syndrome? |
| Does pioglitazone prevent or delay type 2 diabetes and its complications in people at risk of developing type 2 diabetes mellitus? |
| Does placing a tiny tube (microstent) under the surface of the eye relieve long-lasting high pressure inside the eye (glaucoma)? |
| Does platelet-rich plasmapheresis (PRP) reduce the need for donor blood |
| Does pre-emptive treatment with antiviral agents help to reduce the risk of cytomegalovirus disease in transplant recipients? |
| Does pre-transfusion washing of red blood cells for preterm babies improve their health outcomes? |
| Does preconception lifestyle advice help people with infertility to have a baby? |
| Does prophylactic mesh placement around a stoma prevent the development of future hernia and general patient discomfort? |
| Does quarantine, alone or in combination with other public health measures, control coronavirus (COVID-19)? |
| Does quit-smoking support delivered by community pharmacy staff help people to stop smoking? |
| Does random drug and alcohol testing prevent injuries in workers? |
| Does reducing the amount of salt in a diet improve asthma symptoms? |
| Does reducing your salt intake help to prevent and treat chronic kidney disease in people with diabetes? |
| Does reduction of dialysate temperature affect blood pressure during haemodialysis? |
| Does releasing Wolbachia-carrying mosquitoes prevent dengue infection? |
| Does reminding people to have vaccinations increase the number of people who receive vaccinations? |
| Does repair of torn rotator cuff tendons work? |
| Does respiratory syncytial virus (RSV) vaccination during pregnancy reduce RSV-related hospitalisations in infants? |
| Does respiratory syncytial virus (RSV) vaccination during pregnancy reduce RSV-related hospitalisations in infants? |
| Does routine monitoring of stomach aspirates (partially digested milk and gut hormones withdrawn from the feeding tube) avoid necrotising enterocolitis in premature babies? |
| Does selecting targeted therapies based on genetic testing of an individual's cancer prolong their life or delay disease progression in people with advanced cancer? |
| Does shared decision-making help women when making decisions about whether or not to participate in breast cancer screening? |
| Does shared decision-making help women when making decisions about whether or not to participate in breast cancer screening? |
| Does silver acetate help people stop smoking |
| Does smoking in a way that is unpleasant help smokers to quit |
| Does special assessment of older people getting surgery improve their recovery after surgery? |
| Does statin therapy improve survival or reduce risk of heart disease in people on dialysis? |
| Does stopping smoking improve mental health? |
| Does stopping smoking make people with heart disease less likely to have another heart attack? |
| Does subfascial endoscopic perforator surgery (leg-vein surgery) help heal venous leg ulcers? |
| Does supplementation of human milk with calcium and phosphorus improve growth and development in preterm infants? |
| Does support and intervention from nurses help people to stop smoking? |
| Does surgical glue prevent postoperative pancreatic fistula (leaking of fluid from the pancreas) and promote healing after surgery? |
| Does surgical removal of fibroids improve fertility outcomes? |
| Does surgical removal of the lower leg (amputation) through the knee offer patients improved surgical recovery and better rehabilitation than amputation above the knee? |
| Does taking a supplement of myo-inositol work as an effective treatment for women who develop diabetes during pregnancy? |
| Does taking inhaled steorids either before or after being intubated (having a tube down the throat to help you breathe) prevent the painful swelling that can result? |
| Does taking statins prevent blood clots from forming in the veins of people who have not previously had a blood clot? |
| Does taxation of unprocessed sugar or foods with added sugar reduce their consumption and prevent obesity or other adverse health outcomes? |
| Does telephone counselling help people stop smoking? |
| Does testing for cancer in people with unprovoked blood clots in the legs and lungs reduce cancer- and blood clot-related death and illness? |
| Does testosterone work in men who have problems with erections? |
| Does the addition of radiotherapy to chemotherapy improve survival or increase side effects in adults with early-stage Hodgkin's lymphoma compared to chemotherapy alone? |
| Does the administration of nalbuphine provide effective and safe postoperative pain treatment in children? |
| Does the DASH diet help people with or at risk of cardiovascular diseases? |
| Does the design of replacement lenses used in cataract surgery help to stop clouding of the new lens once inside the eye? |
| Does the measles, mumps, rubella and varicella (MMRV) vaccine protect children, and does it cause harmful effects? |
| Does the number of doses of PEG-asparaginase affect survival and risk of toxicities? |
| Does the perioperative administration of tramadol provide effective and safe postoperative analgesia in children? |
| Does the placement of a breathing tube using video assistance (videolaryngoscopy) increase the success and safety of the procedure in newborn babies? |
| Does the placement of a breathing tube using video assistance (videolaryngoscopy) increase the success and safety of the procedure in newborn babies? |
| Does the prescription of low-calorie (hypocaloric) nutrition support improve the recovery of critically-ill adult patients? |
| Does the risk of death differ between female and male adult patients with pulmonary embolism (a blood clot in the lungs)? |
| Does the separation or grouping, or both of newborn infants in the newborn unit decrease spread of infections? |
| Does the speed of injection make a difference in the amount of pain and bruising in people receiving heparin injections? |
| Does the timing and route of nutritional support have an effect on survival and disability in head-injured patients? |
| Does the type of anaesthesia for recanalisation therapies for acute ischaemic stroke affect patient outcomes? |
| Does the use of antibiotics prevent leptospirosis? |
| Does the use of antimicrobial mouthwash or nasal spray by people who are not actively suspected of having COVID-19 - or by their healthcare workers - protect their healthcare workers when they undertake 'aerosol-generating procedures' on them? |
| Does tobacco advertising and promotion make it more likely that adolescents will start to smoke |
| Does tranexamic acid (a medicine used to improve blood clotting) reduce bleeding during endoscopic surgery for chronic rhinosinusitis? |
| Does tranexamic acid given before an operation reduce blood loss for women with advanced ovarian cancer? |
| Does treating obstructive sleep apnoea in children who also have chronic cough improve their cough? |
| Does treating reduced blood flow to the legs using cells taken from the bone marrow help improve symptoms? |
| Does treating Streptococcal throat infection help improve psoriasis? |
| Does treating the coronary arteries of the heart help prevent heart attacks during major blood vessels surgeries? |
| Does treatment for gum disease help people with diabetes control blood sugar levels? |
| Does treatment with GLP-1 receptor agonists prevent complications for people with chronic kidney disease and diabetes? |
| Does treatment with SGLT2 inhibitors prevent complications for people with chronic kidney disease and diabetes? |
| Does undernutrition increase the risk of tuberculosis? |
| Does undernutrition increase the risk of tuberculosis? |
| Does use of an electronic health record improve the delivery of stop smoking treatment to patients? |
| Does use of mouth rinse before a dental procedure reduce the risk of infection transmission from patient to health professional? |
| Does using a thin sheet of rubber (rubber dam) to isolate teeth from the rest of the mouth during a dental procedure improve the success of tooth repairs? |
| Does using low-sodium salt substitutes (LSSS) instead of regular salt reduce blood pressure and heart disease risks, and is it safe? |
| Does using medication to block the hormone oxytocin help women who are undergoing embryo transfer for fertility treatment increase their chance of having a baby? |
| Does using the Xpert MTB/RIF diagnostic test instead of smear microscopy when evaluating people for tuberculosis reduce death and successful treatment completion? |
| Does vitamin D reduce risk of severe asthma attacks or improve control of asthma symptoms? |
| Does vitamin D supplementation benefit, harm, or have no effects on pregnant women or their babies? |
| Does vitamin D supplementation benefit, harm, or have no effects on pregnant women or their babies? |
| Does weekly dosing of paclitaxel improve survival, compared with tri-weekly dosing of paclitaxel in the initial treatment of ovarian cancer? |
| Does written information reduce antibiotic use for upper airway infections among people treated in primary care settings? |
| Does yoga relieve cancer-related fatigue in people with cancer? |
| Domestic violence screening and intervention programmes for adults with dental or facial injury |
| Domiciliary oxygen for chronic obstructive pulmonary disease |
| Domiciliary oxygen for interstitial lung disease |
| Dominican Republic will now have free access to Cochrane Reviews |
| Donate |
| Donepezil for dementia in people with Down Syndrome |
| Donepezil for people with dementia due to Alzheimer's disease |
| Donor organ preservation techniques for kidney transplantation |
| Donor versus no donor comparison of hematopoietic cell transplantation for adult acute lymphoblastic leukemia in first complete remission |
| Dopamine agents for hepatic encephalopathy |
| Dopamine agonist therapy in early Parkinson's disease |
| Dopamine agonists for idiopathic hyperprolactinaemia and prolactinoma in adults |
| Dopamine agonists for preventing future miscarriage in women with high prolactin levels and a history of recurrent miscarriage |
| Dopamine agonists for restless legs syndrome |
| Dopamine agonists for the treatment of people who misuse cocaine |
| Dopamine agonists for traumatic brain injury |
| Dopamine for prevention of morbidity and mortality in term newborn infants with suspected perinatal asphyxia |
| Dopamine transporter imaging for the diagnosis of dementia with Lewy bodies |
| Dopamine versus dobutamine for hypotensive preterm infants |
| Dopamine versus no treatment to prevent renal dysfunction in indomethacin-treated preterm newborn infants |
| Dopaminergic agents versus control for enhancing stroke recovery and rehabilitation |
| Dopaminergic antagonists for alcohol dependence |
| Doppler trans-thoracic echocardiography for detection of pulmonary hypertension in adults |
| Doppler ultrasound for fetal assessment in high risk pregnancies |
| Doppler ultrasound of blood vessels in the placenta and uterus of pregnant women as a way of improving outcome for babies and their mothers |
| Doppler ultrasound of fetal blood vessels in normal pregnancies |
| Doppler ultrasound of fetal vessels in pregnancies at increased risk of complications |
| Doppler ultrasound, CT angiography, MR angiography, and contrast-enhanced MR angiography versus intra-arterial angiography for moderate and severe carotid stenosis in symptomatic patients |
| Dornase alfa, an inhaled drug, for treating lung disease in cystic fibrosis |
| Dosage intervals of amoxicillin for the treatment of acute middle ear infection |
| Dose reduction and discontinuation of biologic and targeted synthetic disease-modifying anti-rheumatic drugs (DMARDs) for people with psoriatic arthritis in remission or low disease activity |
| Dose reduction and discontinuation of biologic and targeted synthetic disease-modifying anti-rheumatic drugs (DMARDs) in people with axial spondyloarthritis and low disease activity |
| Dose reduction and discontinuation of disease-modifying anti-rheumatic drugs (DMARDs) for juvenile idiopathic arthritis |
| Dose-escalated radiotherapy for curative treatment in men with clinically localized prostate cancer |
| Double gloving to reduce surgical cross-infection |
| Double versus single intrauterine insemination for subfertile couples |
| Double wall versus single wall incubator for reducing heat loss in very low birth weight infants in incubators |
| Double-bundle versus single-bundle reconstruction for anterior cruciate ligament rupture in adults |
| Double-stapled anastomosis versus mucosectomy and handsewn anastomosis in ileal pouch-anal anastomosis for ulcerative colitis or familial adenomatous polyposis |
| Doubtful effect of lecithin as a treatment for dementia |
| Doxapram for ventilatory failure due to exacerbations of chronic obstructive pulmonary disease |
| Doxapram treatment for apnea in preterm infants |
| Doxapram versus methylxanthine for apnea in preterm infants |
| Doxazosin for benign prostatic obstruction |
| Doxorubicin after initial treatment for sarcoma reduces risk of recurrence |
| Doxycycline plus ivermectin for preventing and treating river blindness (onchocerciasis) |
| Doxycycline for osteoarthritis |
| Dr Matthew Page on winning the 2018 Bill Silverman Prize |
| Dr. Christian Osadnik wins Monash University 2018 Faculty Early Career Research prize for Cochrane Review |
| Dr. David Tovey awarded Emeritus Editor-in-Chief |
| Drainage tube placement after lymph gland removal from the armpit for breast cancer |
| Drains are often used after thyroid operations. |
| Drains for leg artery surgery |
| Drains increase the harms to patients undergoing open cholecystectomy |
| Drains versus no drains after pelvic lymphadenectomy to prevent lymphocyst formation in women with gynaecological cancer |
| Drama therapy for schizophrenia or schizophrenia-like illnesses |
| Dressings and securement for central venous catheters (CVCs) |
| Dressings and topical agents (gels, ointments and creams) for treating venous leg ulcers |
| Dressings and topical agents for arterial leg ulcers |
| Dressings and topical agents for donor sites of split-thickness skin grafts |
| Dressings and topical agents to help surgical wounds heal by secondary intention |
| Dressings for healing venous leg ulcers |
| Dressings for the prevention of surgical site infection |
| Dressings for treating superficial and partial thickness burns |
| Dressings that use negative pressure for closed surgical wounds |
| Dressings to treat foot ulcers in people with diabetes |
| Drinking extra water or other non-caloric beverages for promoting weight loss or preventing weight gain |
| Driving assessment for maintaining mobility and safety in drivers with dementia |
| Driving rehabilitation for stroke |
| Droperidol for psychosis-induced aggression or agitation |
| Droperidol for the treatment of nausea and vomiting (sickness) in people with advanced disease |
| Drug and nutritional treatment for McArdle disease |
| Drug combinations for chronic neuropathic pain in adults |
| Drug delivery technique using electrical current for the treatment of non-muscle invasive bladder cancer |
| Drug interventions for deliberately altering blood pressure in acute stroke |
| Drug interventions for the treatment of obesity in children and adolescents |
| Drug interventions versus placebo for the treatment of Raynaud’s phenomenon: generic protocol |
| Drug management for acute tonic-clonic convulsions (fits), including convulsive status epilepticus in children |
| Drug or psychological interventions for preventing depression in people with long-term physical conditions |
| Drug therapy for chronic idiopathic axonal polyneuropathy |
| Drug therapy for delirium in terminally ill adults |
| Drug therapy for Mycetoma |
| Drug therapy for obstructive sleep apnoea in adults |
| Drug therapy for pain in amyotrophic lateral sclerosis or motor neuron disease |
| Drug therapy for treating idiopathic thrombocytopenic purpura during pregnancy |
| Drug therapy for treating systemic intravascular activation of coagulation in patients with leukemia |
| Drug therapy to treat high levels of uric acid in people with high blood pressure |
| Drug treatment for borderline personality disorder |
| Drug treatment for children with bedwetting (nocturnal enuresis) but not including the drug types desmopressin or tricyclics |
| Drug treatment for depression in multiple sclerosis |
| Drug treatment for faecal incontinence in adults |
| Drug treatment for familial amyloid polyneuropathy |
| Drug treatment for lower urinary tract symptoms in women with voiding dysfunction |
| Drug treatment for pain in Guillain-Barré syndrome |
| Drug treatment for small abdominal aortic aneurysms |
| Drug treatment for spinal muscular atrophy type I |
| Drug treatment of recurrent abdominal pain in children |
| Drug treatment other than corticosteroids, intravenous immunoglobulin and plasma exchange for acute Guillain Barré syndrome |
| Drug treatments and electronic cigarettes for stopping smoking in pregnancy |
| Drug treatments for apathy in Alzheimer's disease |
| Drug treatments for chronic cognitive impairment in traumatic brain injury |
| Drug treatments for chronic hair-pulling (trichotillomania) |
| Drug treatments for constipation caused by antipsychotic medications |
| Drug treatments for dysthymia |
| Drug treatments for managing cystic fibrosis-related diabetes |
| Drug treatments for pain in children and young people with life-limiting conditions |
| Drug treatments for pain relief in hysterosalpingography |
| Drug treatments for sexual offenders or those at risk of offending |
| Drug treatments for the prevention of attacks of hereditary angioedema |
| Drug treatments that specifically target ammonia for adults with cirrhosis and hepatic encephalopathy |
| Drug treatments to ease breathlessness in cystic fibrosis |
| Drug-based and non-drug-based interventions to improve the bone mineral density in patients living with HIV |
| Drug-eluting balloon angioplasty versus uncoated balloon angioplasty for stenosis of stents in lower limb arteries |
| Drug-eluting bead transarterial chemoembolisation for unresectable hepatocellular carcinoma |
| Drug-eluting stents versus bare metal stents for angina or acute coronary syndromes |
| Drug-eluting stents versus bare-metal stents for non-acute ischaemic heart disease |
| Drugs (with the exception of botulinum toxin) to treat spasticity after stroke |
| Drugs against parasites for prevention of Chagas heart disease |
| Drugs and natural products for self-harm in adults |
| Drugs and natural products for self-harm in adults |
| Drugs and pacemakers for transient loss of consciousness |
| Drugs as treatment for self-injurious behaviour in adults with intellectual disabilities |
| Drugs commonly-used for preventing high altitude illness |
| Drugs for cancer-related fatigue |
| Drugs for discoid lupus erythematosus |
| Drugs for general anaesthesia for caesarean section |
| Drugs for motor complications in people with Parkinson´s disease who are already taking levodopa |
| Drugs for nocturia in adults |
| Drugs for perineal pain in the early postpartum period: generic protocol |
| Drugs for preventing blood clot dissolution (antifibrinolytic therapy) to improve recovery after subarachnoid haemorrhage from a ruptured aneurysm (aneurysmal) |
| Drugs for preventing dry mouth and problems with saliva after radiotherapy |
| Drugs for preventing graft versus host disease |
| Drugs for preventing headache after a lumbar puncture |
| Drugs for preventing hepatitis B recurrence after liver transplantation |
| Drugs for preventing kidney disease in people with diabetes |
| Drugs for preventing lung cancer in healthy people |
| Drugs for preventing major morbidity and mortality related to blood pressure and heart rate changes associated with tracheal intubation |
| Drugs for preventing migraine headaches in children |
| Drugs for preventing nausea and vomiting after surgery |
| Drugs for reducing iron in people with acute stroke |
| Drugs for reducing stomach acid for people with cystic fibrosis |
| Drugs for the acute treatment of migraine in children and adolescents |
| Drugs for the prevention and treatment of pruritus in patients receiving neuraxial opioids |
| Drugs for the prevention of postoperative urinary retention in adults |
| Drugs for treating Buruli ulcer (Mycobacterium ulcerans disease) |
| Drugs for treating giardiasis |
| Drugs for treating giardiasis |
| Drugs for treating headache after a lumbar puncture |
| Drugs for treating people with sleepiness during shift work and sleep problems after shift work |
| Drugs for treating Schistosoma mansoni infection |
| Drugs for treating urinary schistosomiasis |
| Drugs for treatment of urinary retention after surgery in adults |
| Drugs for treatment of very high blood pressure during pregnancy |
| Drugs given to pregnant women and their babies to keep them still during fetal surgery and other invasive procedures on the baby |
