| Discontinuation of epidural analgesia late in labour for reducing the adverse delivery outcomes associated with epidural analgesia |
| Discontinuation of intravenous oxytocin used to stimulate uterine contractions in the active phase of induced labour |
| Discounts announced for Latin American Colloquium registrants |
| Discover Cochrane Engage: Your gateway to volunteering in health evidence work |
| Disease management interventions for improving self-management in lower-limb peripheral arterial disease |
| Disease management programmes for heart failure |
| Disease modifying immunosuppressant drugs for juvenile-onset systemic lupus erythematosus |
| Disease-modifying anti-rheumatic drugs (DMARDs) for Sjogren’s syndrome |
| Disease-modifying anti-rheumatic drugs for rheumatoid arthritis: a systematic review and network meta-analysis |
| Disease-modifying drugs for people with a first clinical attack suggestive of multiple sclerosis |
| Disease-modifying pharmacological treatments for amyotrophic lateral sclerosis/motor neuron disease: an overview of intervention reviews |
| Disease-modifying therapy for HIV-related distal symmetrical polyneuropathy (including antiretroviral toxic neuropathy) |
| Disposable surgical face masks for preventing surgical wound infection in clean surgery |
| Dissection versus diathermy for tonsillectomy |
| Distal aortic perfusion during thoracoabdominal aneurysm repair for prevention of paraplegia |
| Distraction techniques for schizophrenia |
| Disulfiram as a medication for the treatment of cocaine dependence |
| Disulfiram for alcohol use disorder |
| Diuretic therapy for newborn infants with posthemorrhagic ventricular dilatation |
| Diuretics acting on the distal renal tubule for preterm infants with (or developing) chronic lung disease |
| Diuretics effective in lowering blood pressure when given as a second drug |
| Diuretics for heart failure in adults |
| Diuretics for people with chronic kidney disease |
| Diuretics for preventing pre-eclampsia |
| Diuretics for respiratory distress syndrome in preterm infants |
| Diuretics for the treatment of Ménière's disease or syndrome |
| Diuretics for transient tachypnoea of the newborn (TTN) |
| Diverse strategies for preventing high altitude illness |
| DNA technology increases pregnancy rate for women on IVF |
| Do a group of drugs known as monoaminergic agonists help the brain recovery after a severe injury? |
| Do acetylcholinesterase inhibitors reduce the core impairments associated with autism spectrum disorder |
| Do activity monitors help adults with stroke become more physically active? |
| Do acupuncture and related therapies help smokers who are trying to quit |
| Do additional surgical techniques at the lower end of bypasses in the leg improve the chance of the bypass working and saving the leg from amputation? |
| Do amphetamines increase blood pressure? |
| Do antibiotics prevent surgical site infection after breast cancer surgery? |
| Do antidepressants help people with non-specific low-back pain and spine-related leg pain? |
| Do antifungal medicines for vaginal yeast infections (thrush) work better if taken by mouth (orally) or placed in the vagina (intravaginally)? |
| Do antioxidant supplements help people with sickle cell disease (unusually shaped red blood cells)? |
| Do antioxidant vitamin and mineral supplements slow down the progression of age-related macular degeneration (AMD)? |
| Do antioxidant vitamin and mineral supplements slow down the progression of age-related macular degeneration (AMD)? |
| Do antipsychotic medicines reduce agitated behaviour and psychotic symptoms in people with Alzheimer's disease and vascular dementia? |
| Do any treatments help people who have successfully quit smoking to avoid starting smoking again? |
| Do automated mandatory boluses of epidural medications provide superior labour pain relief than basal infusion? |
| Do azole medicines taken as a cream or drops work for treating otomycosis (a fungal ear infection)? |
| Do bans on smoking and intensive educational campaigns reduce smoking in public places |
| Do beds, mattresses and mattress toppers that apply constant pressure to the skin and are not air-filled or made of foam prevent pressure ulcers? |
| Do beds, mattresses and mattress toppers with air-filled surfaces that apply constant pressure to the skin prevent pressure ulcers? |
| Do beds, mattresses and mattress toppers with air-filled surfaces that regularly redistribute pressure under the body prevent pressure ulcers? |
| Do biosimilar monoclonal antibodies perform as well as the original medicine for cancer treatment? |
| Do biosimilar monoclonal antibodies perform as well as the original medicine for cancer treatment? |
| Do blood pressure-lowering medications help protect transplanted kidneys and help prevent heart-related complications? |
| Do blood thinner injections given after abdominal surgery further reduce blood clots if continued after discharge from the hospital? |
| Do blood thinners prevent blood clots in children who are treated using central lines? |
| Do blood thinners prevent people who are hospitalised with COVID-19 from developing blood clots? |
| Do blood thinners prevent people who are hospitalised with COVID‐19 from developing blood clots? |
| Do bone-modifying medicines help reduce bone loss in women with early or locally advanced breast cancer? |
| Do bone-modifying medicines help reduce bone loss in women with early or locally advanced breast cancer? |
| Do braces correct or improve 'underbite' (prominent lower front teeth) in children and teens? |
| Do burns patients who receive early (within 24 hours) nutritional support have better outcomes than those whose nutritional support is delayed (after 24 hours)? |
| Do calcium supplements during pregnancy improve the health of babies and mothers (omitting studies on high blood pressure) |
| Do calcium supplements help people with overweight or obesity lose weight? |
| Do cancer vaccines help people with advanced non-small cell lung cancer? |
| Do combined inhalers (steroid plus bronchodilator) offer additional benefits or harms in people with COPD compared with the bronchodilator alone? |
| Do competitions help smokers to quit in the medium to long term? |
| Do courses aimed at improving the way healthcare professionals communicate with people who have cancer impact on their physical and mental health? |
| Do diet and physical activity strategies help prevent obesity in children (aged 0 to 18 years)? |
| Do dietary and activity strategies help prevent obesity in children aged 5 to 11 years? |
| Do dietary and activity strategies help prevent obesity in children and young people aged 12 to 18 years? |
| Do different methods of nutritional support affect recovery and complications in adults after pancreaticoduodenectomy? |
| Do different settings and techniques for measuring blood pressure during pregnancy help to improve outcomes for women and babies? |
| Do different ways of giving blood or blood products to treat bleeding affect the risk of death or the risk of developing a blood clot in people who are bleeding heavily after a traumatic injury? |
| Do digital technologies help people with cystic fibrosis stick to their inhaled treatments? |
| Do dressings and securement devices prevent complications for people with peripheral arterial catheters? |
| Do drugs that enhance the beating force of the heart prevent low cardiac output syndrome and death in children undergoing surgery for congenital heart disease? |
| Do drugs that suppress the immune system improve outcomes in those with or at risk from atherosclerosis? |
| Do early intervention programmes improve physical and mental development in babies born too early? |
| Do earplug fit tests plus training on how to fit earplugs help people who work in noisy environments? |
| Do education and training programs reduce aggressive behavior toward healthcare workers? |
| Do education programmes improve outcomes in people with both chronic kidney disease and diabetes? |
| Do electronic or robotic gait-training devices help people walk better after a stroke? |
| Do epidermal growth factor receptor (EGFR) inhibitors, alone or with chemotherapy, improve outcomes for women with epithelial ovarian cancer (EOC)? |
| Do epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs) after lung cancer surgery help people live longer and prevent cancer from returning? |
| Do group-based smoking cessation programmes help people to stop smoking? |
| Do H1 antihistamine tablets or liquids help improve eczema symptoms in people who are already using creams or ointments for their eczema? |
| Do health education interventions lead to early treatment for women with symptoms of endometrial (womb) cancer |
| Do health promotion programmes in the workplace increase people's physical activity if they include a pedometer? |
| Do heart surgery patients benefit from preventive treatment with inotropic drugs? |
| Do heated tobacco products help people to quit smoking, are they safe for this purpose, and have they led to falls in smoking rates? |
| Do imitations of anti-VEGF medicines (biosimilars) work as well as the original anti-VEGF medicines for people with neovascular age-related macular degeneration (nAMD)? |
| Do imitations of anti-VEGF medicines (biosimilars) work as well as the original anti-VEGF medicines for people with neovascular age-related macular degeneration (nAMD)? |
| Do incentives help keep young people from starting to smoke in the medium to long term? |
| Do inhaled corticosteroids reduce growth in children with persistent asthma? |
| Do inhaled steroids increase the risk of pneumonia in people with chronic obstructive pulmonary disease (COPD)? |
| Do injectable pneumococcal vaccines prevent pneumonia in people with COPD? |
| Do interventions in families prevent children and adolescents from starting to smoke |
| Do interventions that reduce the cost of smoking cessation treatment increase quit rates, quit attempts or use of treatments? |
| Do interventions to enhance one-to-one support provided by partners, family members, or 'buddies' help smokers quit? |
| Do interventions to help adults stop smoking cigarettes work differently depending on people’s socioeconomic background? |
| Do interventions to stop children and adolescents from using electronic cigarettes work? |
| Do intravenous antibiotics improve pulmonary exacerbations (flare-ups) in people with cystic fibrosis? |
| Do invitations, lay health worker interventions and educational interventions increase the uptake of cervical screening? |
| Do local anaesthetic nerve blocks provide effective pain relief for adults with a hip fracture? |
| Do long-term antibiotics help to reduce rheumatic fever recurrence and progression of rheumatic heart disease? |
| Do low blood pressure targets provide additional benefits for people with chronic kidney disease and high blood pressure compared to standard targets? |
| Do low glycaemic index or low glycaemic load diets help people with overweight or obesity to lose weight? |
| Do magnesium sulfate infusions reduce the need for hospital admission in adults with acute asthma? |
| Do magnesium sulfate infusions reduce the need for hospital admission in children with acute asthma? |
| Do mattresses and mattress toppers made of foam prevent pressure ulcers? |
| Do measures that aim to reduce aerosol production during dental procedures prevent the transmission of infectious diseases? |
| Do media campaigns prevent young people from using illicit drugs? |
| Do medicinal interventions reduce radiation-related bone fractures and risk of avascular necrosis in adults undergoing pelvic radiotherapy? |
| Do medicines for anaemia help prevent acute kidney injury? |
| Do medicines for depression help people to quit smoking? |
| Do medicines for weight loss affect blood pressure, and reduce the effects of high blood pressure (hypertension)? |
| Do medicines that restrict new blood vessel growth (angiogenesis inhibitors) help women with epithelial ovarian cancer? |
| Do mobility strategies improve and restore mobility after hip fracture surgery in adults? |
| Do mobility strategies improve and restore mobility after hip fracture surgery in adults? |
| Do nasal decongestants used alone relieve cold symptoms? |
| Do newer laser treatments work better than standard laser treatments for proliferative diabetic retinopathy? |
| Do non-corticosteroid immunosuppressive medicines for steroid-sensitive nephrotic syndrome in children help prevent relapse? |
| Do nonsteroidal anti-inflammatory drugs (NSAIDs) increase the risk of bleeding in children having their tonsils out? |
| Do nutritional interventions reduce gastrointestinal toxicity in adults undergoing radical pelvic radiotherapy? |
| Do opioid antagonists such as naltrexone help people to stop smoking? |
| Do organizational changes to support people quitting smoking improve services and help more people to quit? |
| Do painkillers rubbed on the skin really work? |
| Do PARP inhibitors improve survival in women with ovarian cancer, and what are the side effects? |
| Do patients manage their health care better if they can access their electronic health records? |
| Do people recover from exacerbations of chronic obstructive pulmonary disease (COPD) better in their own home than in the hospital emergency room? |
| Do people with asthma have fewer serious adverse events when taking formoterol and inhaled corticosteroids compared to salmeterol and inhaled corticosteroids? |
| Do people with type 1 diabetes mellitus benefit from using a different type of insulin as their basal insulin? |
| Do pharmacological and non-pharmacological strategies reduce weight in obese women with subfertility? |
| Do pharmacotherapies which reduce anxiety help smokers to quit |
| Do physical activity interventions in outside-school hours care services help increase children's overall daily physical activity? |
| Do physical measures such as hand-washing or wearing masks stop or slow down the spread of respiratory viruses? |
| Do pressure redistributing static chairs help to prevent pressure ulcers? |
| Do printed self-help materials help people to quit smoking? |
| Do probiotics help to treat acute infectious diarrhoea? |
| Do programmes offered through sporting organisations promote healthy behaviour and improve people's health? |
| Do proton pump inhibitors prevent ulcers and stomach discomfort caused by non-steroidal anti-inflammatory drugs? |
| Do psychological and social interventions prevent mental health disorders in low- and middle-income countries affected by humanitarian crises? |
| Do psychological and social interventions promote improved mental health in people living in low- and middle-income countries affected by humanitarian crises? |
| Do psychological interventions reduce depression and anxiety in patients with coronary heart disease, heart failure or atrial fibrillation compared to no psychological intervention? |
| Do psychological interventions work for people with both depression and substance use disorders? |
| Do psychological therapies help diabetic foot ulcers to heal and prevent their recurrence? |
| Do psychosocial interventions help parents reduce how often they drink heavily or use drugs? |
| Do psychosocial treatments help people with stimulant use disorder? |
| Do psychosocial treatments help people with stimulant use disorder? |
| Do school tobacco policies prevent uptake of smoking? |
| Do school-based physical activity interventions increase moderate to vigorous physical activity and improve physical fitness among children and adolescents? |
| Do school-based physical activity interventions increase moderate to vigorous physical activity and improve physical fitness among children and adolescents? |
| Do services to support the education of children and teenagers with chronic health conditions help to engage them more in school activities and improve learning outcomes? |
| Do short periods of artificially blocking blood flow to the limbs in people undergoing vascular surgery reduce death and organ injury? |
| Do smoking bans at an institutional level help to stop people smoking? |
| Do social support interventions help people with heart disease? |
| Do speed cameras reduce road traffic crashes, injuries and deaths? |
| Do statins prevent kidney failure in adults after surgery where cardiac bypass is used? |
| Do strengthening exercises help in the treatment of people with patellar tendinopathy (jumper's knee)? |
| Do supplements (like lutein and zeaxanthin) reduce illnesses and death in preterm infants? |
| Do supportive, educational and behavioural interventions improve usage of continuous positive airway pressure in adults with obstructive sleep apnoea? |
| Do synbiotics prevent necrotising enterocolitis in very preterm or very low birth weight infants? |
| Do systemic corticosteroids improve treatment outcomes in flare-ups of chronic obstructive pulmonary disease? |
| Do tobacco cessation interventions provided during substance abuse treatment or recovery help tobacco users to quit? |
| Do treatment effects in randomised trials differ when using active placebo compared to standard placebo? |
| Do typhoid conjugate vaccines prevent acute typhoid fever and are they safe? |
| Do upper limb exercise programs work for arteriovenous fistula maturation in people with kidney failure? |
| Do vaginal packing, tranexamic acid, interventional radiology or other interventions control vaginal bleeding in women with advanced cervical cancer? |
| Do ventilators that manage the reduction of ventilator support (weaning) reduce the duration of weaning compared to strategies managed by clinicians? |
| Do video-assisted instruments for inserting breathing tubes in adults work better than direct-view instruments and do they cause unwanted effects? |
| Do video-assisted instruments for inserting breathing tubes in adults work better than direct-view instruments and do they cause unwanted effects? |
| Do weight loss programs have beneficial effects on asthma outcomes in people with asthma? |
| Do weight-loss diets affect blood pressure, and reduce the effects of high blood pressure (hypertension)? |
| Doctors and patients making decisions together could reduce the number of antibiotics prescribed for acute respiratory infections |
| Does 5-ASA prevent the recurrence of diverticulitis? |
| Does a combination of stop smoking medication and behavioural support help smokers to stop? |
| Does a group of drugs known as calcium channel blockers reduce mortality and unfavourable complications in patients with traumatic brain injury? |
| Does a local anaesthetic injection in children and young people having dental treatment under general anaesthetic reduce pain after treatment? |
| Does a strategy of extended-duration blood thinners for preventing the development of blood clots in the legs and lungs improve the outcomes of patients admitted to the hospital for an acute medical illness? |
| Does a tax on the fat content of foods reduce obesity and help people to eat less fat and less saturated fat? |
| Does adding a long-acting muscarinic antagonist (LAMA) to an inhaled steroid help people with uncontrolled asthma more than an inhaled steroid alone? |
| Does adding antileukotriene agents to usual care when people are suffering an asthma attack in the emergency department help? |
| Does adding fluoride to water supplies prevent tooth decay? |
| Does adding iron to wheat flour reduce anaemia and increase iron levels in the general population? |
| Does adding rapid diagnostic tests to community-based malaria programmes improve the treatment of people with malaria or fever? |
| Does adding tiotropium, a long-acting muscarinic antagonist (LAMA), to combination therapy (LABA/ICS) help to control asthma? |
| Does administering colony-stimulating factors plus antibiotics in people with fever and low white cell count reduce hospitalization? |
| Does advice from doctors encourage people who smoke to quit |
| Does alendronate help prevent fractures caused by osteoporosis in postmenopausal women? |
| Does altering the dose of inhaled corticosteroids make a difference in growth among children with asthma? |
| Does an aminophylline injection in addition to bronchodilators for an asthma attack improve lung function and other outcomes or cause harm? |
| Does banning or restricting advertising for alcohol result in less drinking of alcohol? |
| Does behavioural support help people to stop smoking? |
| Does breastfeeding reduce vaccination pain in babies aged 1 to 12 months? |
| Does cardiovascular training relieve cancer-related fatigue before, during, or after anticancer therapy? |
| Does chewing gum after a caesarean section lead to quicker recovery of bowel function? |
| Does chromoscopy (dye-spraying) improve rates of polyp detection when compared to conventional colonoscopy? |
| Does cleaning hands with ash stop or reduce the spread of viral and bacterial infections compared with soap or other materials? |
| Does cleaning venous leg ulcers help them to heal? |
| Does clonidine help smokers to quit |
| Does collective leadership improve healthcare professionals' actions, patient health care and staff well-being? |
| Does communicating DNA-based risk estimates motivate people to change their behaviour? |
| Does controlling exposure to house dust mites improve asthma? |
| Does Daikenchuto reduce postoperative ileus in persons undergoing elective abdominal surgery? |
| Does daily sedation interruption reduce the time critically ill adults spend on breathing machines compared to other sedation strategies? |
| Does daily treatment with formoterol result in more serious adverse events compared to placebo or daily salbutamol? |
| Does daily treatment with salmeterol result in more serious adverse events compared with placebo or a salbutamol? |
| Does deep muscle relaxation during laparoscopic surgery improve outcomes? |
| Does delaying cord clamping or using cord milking at birth improve the health of babies born too early? |
| Does delaying the initiation or starting calcineurin inhibitors at a lower dose reduce the risk of delayed recovery of a transplanted kidney? |
| Does delivery of home care by outreach nurses improve outcomes for people with chronic obstructive pulmonary disease? |
| Does denser compared to normal bupivacaine, given as a lower back injection, give more effective and safer anaesthesia during caesarean section |
| Does dermoscopy improve the accuracy of diagnosing basal cell or squamous cell skin cancer (BCC or cSCC) compared to using the naked eye alone? |
| Does diabetes increase the risk of tuberculosis? |
| Does diabetes increase the risk of tuberculosis? |
| Does dietary fibre prevent the recurrence of colorectal adenomas and carcinomas? |
| Does donor human milk prevent severe bowel disorders in very preterm or very low-birthweight infants? |
| Does electromagnetic field stimulation help heal fractures that are failing or have failed to heal? |
| Does encouraging people to wash their hands stop them having diarrhoea? |
| Does enhanced external counterpulsation reduce symptoms of chronic and refractory angina pectoris? |
| Does etidronate prevent fractures caused by osteoporosis in postmenopausal women? |
| Does exercise after surgery to restore or improve blood circulation to the legs help people with peripheral arterial disease? |
| Does exposure to the smell and taste of milk accelerate feeding in tube-fed preterm infants? |
| Does extended-field radiotherapy reduce death from locally advanced cervical cancer and what are the side effects? |
| Does follow-up with ultrasound after lower limb arterial vascular surgery improve limb salvage rate and maintenance of the open artery? |
| Does galantamine help people with dementia due to Alzheimer's disease and people with mild cognitive impairment? |
| Does galantamine help people with dementia due to Alzheimer's disease and people with mild cognitive impairment? |
| Does giving chemotherapy before surgery improve survival or quality of life in women with advanced epithelial ovarian cancer? |
| Does giving chemotherapy straight away or waiting for symptoms prolong life for persons who have incurable colorectal cancer without symptoms? |
| Does giving chemotherapy, radiotherapy or both improve survival in people with rare (anaplastic oligodendrogliomas and oligoastrocytomas) brain tumours? |
| Does giving daily small, steadily increasing amounts of egg protein help people with egg allergy? |
| Does giving money to people, in low- and middle-income countries, without conditions attached lead to better health and other life improvements? |
| Does giving patients carbohydrate supplements before planned surgery lead to improved recovery? |
| Does giving people feedback on the effects of smoking on their body help them quit smoking? |
| Does group therapy improve well-being in people living with HIV? |
| Does haemodialysis membrane type influence outcomes in people with kidney disease? |
| Does hair removal before surgery prevent infections after surgery? |
| Does heparin locking prevent blocking of central venous catheters in adults when compared to locking with normal saline? |
| Does hormone therapy help transgender women undergoing gender reassignment to transition? |
| Does hormone therapy improve sexual function in women going through or after menopause? |
| Does HPV vaccination prevent the development of cervical cancer? Are there harms associated with being vaccinated? |
| Does hyperbaric oxygen therapy improve outcome after heart attack? |
| Does hyperbaric oxygen therapy improve the survival and quality of life in patients with traumatic brain injury? |
| Does hypnotherapy help people who are trying to stop smoking? |
| Does individually-delivered counselling help people to stop smoking? |
| Does legislation to ban smoking reduce exposure to secondhand smoke and smoking behaviour? |
| Does limiting the times you eat (intermittent fasting) prevent cardiovascular disease? |
| Does mecamylamine help people to stop smoking |
| Does meditation help prevent people from developing cardiovascular disease or from worsening cardiovascular disease? |
| Does meditation help prevent people from developing cardiovascular disease or from worsening cardiovascular disease? |
| Does moisturising baby skin prevent eczema or food allergies? |
