Non-pharmacological care for opioid withdrawal in newborns

To evaluate the efficacy and safety of non-pharmacological treatment of infants at risk for or having symptoms of opioid withdrawal on the need for pharmacological treatment and hospitalization.

Comparison 1: In infants at risk for or having early symptoms of opioid withdrawal, does non-pharmacological treatment reduce the need for pharmacological treatment and reduce the length of hospitalization?

Comparison 2: In infants on pharmacological treatment for symptoms of opioid withdrawal, does concurrent non-pharmacological treatment reduce duration of pharmacological treatment, maximum and cumulative doses of opioid medication, and length of hospitalization?

This is a protocol.

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