To assess the benefits and harms of fibrin-based haemostatic agents in reducing intraoperative blood loss in adults undergoing liver resection.
This is a protocol.
Fibrin-based haemostatic agents for reducing blood loss in adult liver resection
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- Haemodilution shows promise in decreasing blood loss and blood transfusion requirements during liver resection
- No evidence that ischaemic preconditioning has a protective role in liver resections performed utilising vascular occlusion.
- Further trials are necessary to find the optimal method of vascular occlusion in liver resection
- No clear evidence that any pharmacological intervention is better than another in decreasing ischaemia reperfusion injury in liver resections
- Pharmacological interventions show potential for a protective role against ischaemia-reperfusion injury in liver resections
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