Methods to reduce shoulder pain after gynaecological keyhole surgery |
Methotrexate alone or in combination with other medications for rheumatoid arthritis |
Methotrexate alone versus methotrexate in combination with other medications for rheumatoid arthritis |
Methotrexate as a steroid sparing agent for asthma in adults |
Methotrexate for ankylosing spondylitis |
Methotrexate for giant cell arteritis |
Methotrexate for high-grade osteosarcoma in children and young adults |
Methotrexate for keeping ulcerative colitis inactive |
Methotrexate for patients with primary biliary cirrhosis |
Methotrexate for polymyalgia rheumatica |
Methotrexate for psoriasis |
Methotrexate for psoriatic arthritis |
Methotrexate for treating rheumatoid arthritis |
Methotrexate for treatment of active treatment resistant Crohn's disease |
Methotrexate for treatment of chronic active ulcerative colitis |
Methotrexate for treatment of inactive Crohn's disease |
Methyldopa reduces blood pressure in people with high blood pressure |
Methylene blue for treating malaria |
Methylphenidate for attention deficit hyperactivity disorder (ADHD) in children and adolescents - assessment of harmful effects |
Methylxanthine for preventing morbidity and mortality in preterm infants: a network meta-analysis |
Methylxanthine treatment for apnoea in preterm infants |
Methylxanthines for exacerbations of chronic obstructive pulmonary disease |
Methylxanthines for prolonged non-specific cough in children |
Metoclopramide for accurate placement of naso-enteral feeding tube |
Metoclopramide for chronic nausea in adult palliative care patients with advanced cancer |
Metoclopramide, thickened feedings, and positioning for gastro-oesophageal reflux in children under two years |
Metrifonate for Alzheimer's disease |
Metronidazole for pain after haemorrhoid surgery |
mHealth-delivered education interventions in heart failure, using smartphone, tablet and internet-based programmes and apps |
mHealth-delivered education interventions in heart failure, using smartphone, tablet and internet-based programmes and apps |
Micro-invasive treatments for managing dental decay on adjacent tooth surfaces in children's and adults' teeth |
Microfinance-based interventions for health outcomes in persons of low socio-economic status |
Micronutrient supplementation for children with HIV infection |
Micronutrient supplementation interventions to reduce harm in pregnant and lactating women living with HIV |
Micronutrient supplements for non-pregnant adults with HIV infection |
Microwave coagulation for liver metastases |
Microwave therapy for cervical ectropion |
Mid-level health workers for improving the delivery of health services |
Mid-urethral sling operations for stress urinary incontinence in women |
Midazolam for sedation before procedures |
Midline or off-midline wound closure techniques: which works better to treat pilonidal sinus disease? |
Mifepristone for induction of labour |
Mifepristone for uterine fibroids |
Milk boosters (galactagogues) for mothers breastfeeding their healthy infants born at term |
Millions of lives could be saved if health evidence and communication is put at forefront of pandemic preparedness |
Milnacipran for fibromyalgia in adults |
Milnacipran for neuropathic pain in adults |
Milnacipran versus other antidepressive agents for depression |
Milrinone for persistent pulmonary hypertension of the newborn |
Milrinone for the treatment of cardiac dysfunction in neonates |
Milrinone to prevent reduced heart function and death after heart surgery in children |
Mind-body interventions during pregnancy for preventing or treating women's anxiety |
Mind-body movement therapies for Parkinson's disease |
Mindfulness for improving mental well-being in medical students and junior doctors |
Mindfulness-based interventions for adults with type 2 diabetes mellitus |
Mindfulness-based interventions for substance use disorders |
Mindfulness-based stress reduction for family carers of people with dementia |
Mindfulness-based stress reduction for women with breast cancer |
Mindfulness-enhanced parenting programs for improving outcomes for children and their parents |
Mindfulness-enhanced parenting programs for improving outcomes for children and their parents |
Mini keyhole operation versus standard keyhole operation for removal of the gallbladder |
Mini-Mental State Examination (MMSE) for the detection of dementia in people aged over 65 |
Minimal access drainage procedures for patients with necrotising pancreatitis |
Minimally invasive (keyhole) surgery versus radiotherapy alone or radiotherapy and chemotherapy for early-stage throat cancer |
Minimally invasive parathyroidectomy versus bilateral neck exploration for primary hyperparathyroidism in adults |
Minimally invasive surgery (robotic or laparoscopic) versus laparotomy for advanced ovarian cancer |
Minimally invasive surgery compared to open surgery for the treatment of solid tumours located in the chest or the abdomen of children |
Minimally invasive surgical approaches for total hip arthroplasty in adults with osteoarthritis |
Minimally invasive surgical techniques for kidney transplantation |
Minimally invasive surgical techniques versus open myomectomy for uterine fibroids |
Minimally invasive trabecular meshwork surgery for open-angle glaucoma |
Minimally invasive treatments to dissolve blood clots in the lungs (acute pulmonary embolism) |
Minimally invasive versus surgical treatment of an aneurysm of the popliteal artery |
Minocycline for acne vulgaris: efficacy and safety |
Minocycline for amyotrophic lateral sclerosis or motor neuron disease |
Mirror therapy for improving movement after stroke |
Mirror therapy, graded motor imagery and virtual illusion for the management of chronic pain |
Mirtazapine as an add-on treatment for schizophrenia |
Mirtazapine for treating fibromyalgia in adults |
Mirtazapine versus other antidepressive agents for depression |
Miscellaneous treatments for antipsychotic-induced tardive dyskinesia |
Misoprostol for cervical priming prior to IUD insertion in nulliparous women |
Misoprostol for induction of labour to terminate pregnancy in the second or third trimester for women with a fetal anomaly or following intrauterine fetal death |
Misoprostol for intrauterine device placement |
Mistletoe extracts for cancer treatment |
Mistletoe treatment in cancer patients |
Mitomycin C for glaucoma surgery |
Mitomycin C for prevention of postoperative haze following excimer laser surface ablation in moderate to high myopia |
Mitomycin C versus 5-Fluorouracil for wound healing in glaucoma surgery |
Mixed exercise programmes for adults with fibromyalgia |
Mobile clinics for women's and children's health |
Mobile health (m-health) technological support for women during pregnancy or the first six weeks postpartum, or both |
Mobile learning for delivering health professional education |
Mobile phone messaging - a telemedicine for people with diabetes mellitus |
Mobile phone messaging for communicating results of medical investigations |
Mobile phone messaging for facilitating self-management of long-term illnesses |
Mobile phone messaging for preventive health care |
Mobile phone messaging reminders for attendance at healthcare appointments |
Mobile phone text messaging for the prevention of sexually transmitted infections |
Mobile phone text messaging to help patients with HIV infection take their antiretroviral medications every day |
Mobile-based technologies to support client to healthcare provider communication and management of care |
Mobility management interventions to prevent, reduce, or delay driving in teenagers |
Mobility training for increasing mobility and functioning in older people who are frail |
Modafinil for excessive daytime sleepiness |
Modafinil for schizophrenia |
Model for end stage liver disease for prediction of mortality in people with cirrhosis |
Models of care for managing non-specific low back pain |
Moderately early (7-14 days) postnatal corticosteroids for preventing chronic lung disease in preterm infants |
Modern combined oral contraceptives for treatment of pain associated with endometriosis |
Modern radiotherapy techniques versus three-dimensional conformal radiotherapy for head and neck cancer |
Modest salt reduction lowers blood pressure in all ethnic groups at all levels of blood pressure without adverse consequences |
Modifications of the Epley manoeuvre for benign paroxysmal positional vertigo (BPPV) |
Modifying the consistency of food and fluids for swallowing difficulties in dementia |
Modifying therapies such as biologics, colchicine, corticosteroids, immunosuppressants and interferon-alpha for Neuro-Behçet's Syndrome |
Mohs micrographic surgery versus surgical excision for periocular basal cell carcinoma |
Molecular tests to detect infections in newborn babies |
Molindone for schizophrenia and severe mental illness |
Molnupiravir for treating COVID-19 |
Momordica charantia for type 2 diabetes mellitus |
Monetary incentives for schizophrenia |
Monitoring a baby's heart rate during labour with and without a computerised decision aid: a comparison of pregnancy outcomes |
Monitoring of stimulated cycles in fertility treatment involving in vitro fertilisation (IVF) and intra-cytoplasmic sperm injection (ICSI) |
Monitoring pregnant women at home for detecting preterm labour |
Mono and multifaceted allergen reducing interventions for the primary prevention of asthma in children at high risk of developing asthma |
Monoamine oxidase B inhibitors compared with other treatments in early Parkinson's |
Monoamine oxidase B inhibitors for early Parkinson's disease |
Monoamine oxidase inhibitors (MAOIs) for fibromyalgia |
Monoamniotic twins (sharing the same amniotic sac): do they do better if born early? |
Monosodium glutamate (MSG) avoidance for chronic asthma in adults and children |
Montreal Cognitive Assessment (MoCA) for the detection of dementia |
Mood stabilisers for schizoaffective disorder |
More chemotherapy helps women with advanced endometrial cancer; however, the best combination of chemotherapy drugs is still not clear |
More evidence is needed to show whether or not altering the physical home environment by removing potential hazards reduces injuries |
More evidence needed as to the best concentration of crystalloid to use in resuscitation fluids |
More research is needed into the effectiveness of printed educational materials for changing health care practice |
More than 10,000 users in its first month: Cochrane's COVID-19 Study Register supports rapid evidence synthesis in the global challenge to combat COVID-19 |
More than 1300 people from 75 countries gathered for the first ever Global Evidence Summit |
Morita therapy for anxiety disorders in adults |
Morita therapy for schizophrenia |
Morning versus evening induction of labour for improving outcomes for women and their babies |
Morphine for neuropathic pain in adults |
Morphine injections for pain relief after knee arthroscopy |
Morphine-like drugs for cancer pain |
Mosquito repellents for malaria prevention |
Mosquitoes and malaria: Cochrane is on the case |
Most antidepressants prescribed for chronic pain lack reliable evidence of efficacy or safety, scientists warn |
Most prokinetic drugs routinely used to support bowel recovery after major abdominal surgery are not supported by current research evidence |
Most widely followed COPD guideline updates their recommendations with Cochrane Airways reviews |
Mother and baby outcomes following normal delivery and caesarean (c-section) delivery in women with bleeding disorders and carriers |
Mother and baby units for schizophrenia |
Mother-to-child transmission (MTCT) of HIV is the primary way that children become infected with HIV. More than 2000 children worldwide are infected in this way every day. |
Mothers' position during the first stage of labour |
Mothers' positions in labour when baby is lying 'back-to-back' |
Motivational interviewing (MI) for preventing alcohol misuse in young adults is not effective enough |
Motivational interviewing for improving recovery after stroke |
Motivational interviewing for young people living with HIV |
Motor control exercise for acute non-specific low back pain |
Motor control exercise for chronic non-specific low-back pain |
Motor imagery for gait rehabilitation |
Motor neuroprosthesis for improving activities and participation of people in their natural environment after stroke |
Motorcycle helmet legislation for preventing injuries in motorcyclists |
Motorcycle rider training for preventing road traffic crashes |
Moulded foot insoles for adults with pain around the knee cap |
Mouth care for preventing pneumonia in nursing homes |
Mouthrinses for the treatment of halitosis |
Moxibustion for alleviating side effects of chemotherapy or radiotherapy in people with cancer |
Moxibustion for stroke rehabilitation |
Moxibustion for turning a baby in breech position |
MRI scoring indices for evaluation of disease activity and severity in Crohn’s disease |
MRI versus CT for detecting cartilage invasion in patients with laryngeal and hypopharyngeal squamous cell carcinoma |
MRI versus CT versus 18F-FDG PET-CT for detecting lymph node metastases in patients with head and neck squamous cell carcinoma |
Mu-opioid antagonists for bowel dysfunction due to opioids in people with cancer and people receiving palliative care |
Mucolytic agents for chronic bronchitis or chronic obstructive pulmonary disease |
Mucolytic drugs (to help make phlegm easier to cough up) for people with bronchiectasis |
Mucolytics for children with chronic suppurative lung disease |
Mulberry therapy for type 2 diabetes mellitus |
Multi-media social marketing campaigns to increase HIV testing uptake among men who have sex with men and transgender women |
Multi-nutrient fortification of breast milk for preterm infants |
Multicomponent fortification of human breast milk for preterm infants following hospital discharge |
Multidimensional rehabilitation programmes for adult cancer survivors |
Multidisciplinary biopsychosocial rehabilitation for neck and shoulder pain among working age adults. |
Multidisciplinary care for adults with amyotrophic lateral sclerosis (ALS)/motor neuron disease (MND) |
Multidisciplinary rehabilitation after brain tumour treatment |
Multidisciplinary rehabilitation as supportive treatment for adults with multiple sclerosis |
Multidisciplinary rehabilitation for fibromyalgia and musculoskeletal pain in working age adults |
Multidisciplinary rehabilitation for follow-up of women treated for breast cancer |
Multidisciplinary rehabilitation for Parkinson’s disease |
Multidisciplinary rehabilitation programmes following joint replacement at the hip and knee in chronic arthropathy |
Multidisciplinary rehabilitation programmes following treatment of spasticity after stroke |
Multidisciplinary treatment at the early stages of low back pain |
Multidisciplinary treatment for back pain |
Multidiscliplinary care for Guillain-Barré syndrome |
Multifaceted behavioral interventions to improve treatment adherence of glaucoma |
Multifocal versus monofocal intraocular lenses for people having cataract surgery |
Multimedia programs for educating patients about medications |
Multimedia-delivered cognitive behavioural therapy versus face-to-face cognitive behavioural therapy for depression in adults |
Multimodal interventions for cachexia management |
Multimodality treatment for malignant pleural mesothelioma (primary pleural cancer) |
Multiple drug combinations of bortezomib, lenalidomide and thalidomide for initial treatment of adults with transplant-ineligible multiple myeloma |
Multiple micronutrient supplementation for breastfeeding women for improving outcomes for the mother and her baby |
Multiple perceptions about implementing hospital at home |
Multiple risk factor interventions for coronary heart disease |
Multiple session early psychological interventions for prevention of post-traumatic stress disorder |
Multiple versus single lumen umbilical venous catheters for newborn infants |
Multiple vs. single doses of exogenous surfactant for the prevention or treatment of neonatal respiratory distress syndrome |
Multiple-micronutrient supplementation for women during pregnancy |
Muscle energy technique (MET) for non-specific low-back pain |
Muscle relaxants for non-specific low-back pain |
Muscle relaxants for pain management in rheumatoid arthritis |
Muscle stimulation for people with anterior knee pain |
Muscle stimulation for people with chronic obstructive pulmonary disease (COPD) |
Muscle stimulation for weakness in adults with advanced disease |
Muscle strengthening for children and adults with cerebral palsy |
Music during caesarean section under regional anaesthesia for improving maternal and infant outcomes |
Music education for improving reading skills in children and adolescents with dyslexia |
Music for insomnia in adults |
Music for insomnia in adults |
Music for pain relief |
Music for pain relief |
Music interventions for acquired brain injury |
Music interventions for mechanically ventilated patients |
Music therapy for attention deficit hyperactivity disorder (ADHD) in children and adolescents |
Music therapy for autistic people |
Music therapy for depression |
Music therapy for end-of-life care |
Music therapy for people with substance use disorder |
Music therapy for schizophrenia or schizophrenia-like disorders |
Music therapy strikes a chord |
Music to reduce stress and anxiety for people with coronary heart disease |
Music-based therapeutic interventions for people with dementia |
MVA85A vaccine as a booster to BCG for prevention of tuberculosis |
My OCD story: evidence-based medicine to the rescue! |
Mycophenolate mofetil (MMF) for the treatment of connective tissue disease-associated interstitial lung disease (ILD) |
Mycophenolate mofetil for induction of remission in Crohn's disease |
Mycophenolate mofetil for liver-transplanted patients |
Mycophenolate mofetil for relapsing-remitting multiple sclerosis |
Mycophenolate mofetil versus methotrexate for prevention of graft-versus-host disease following allogeneic hematopoietic stem cell transplantation |
Mycophenolic acid versus azathioprine as primary immunosuppression for kidney transplant recipients |
Myeloid growth factors for patients with myelodysplastic syndromes |
Myofunctional therapy (oropharyngeal - mouth and throat - exercises) for people with obstructive sleep apnoea |
N-acetylcarnosine (NAC) drops for age-related cataracts |
N-acetylcysteine for acute liver failure not caused by paracetamol overdose |
N-acetylcysteine taken with antibiotics for treatment of Helicobacter pylori infection |
Naftidrofuryl for acute stroke |
Naftidrofuryl for intermittent claudication |
Naftopidil for the treatment of lower urinary tract symptoms compatible with benign prostatic hyperplasia |
Naloxone for hepatic encephalopathy |
Naloxone for opioid-exposed newborn infants |
Naloxone for preventing morbidity and mortality in newborn infants of greater than 34 weeks' gestation with suspected perinatal asphyxia |
Naloxone for reducing mortality and adverse neurological outcomes following acute traumatic brain injury |