Naloxone may improve blood pressure in people who are in shock but more trials are needed to show whether this reduces deaths |
Naltrexone and nalmefene for alcohol dependent patients |
Naltrexone for cocaine dependence treatment |
Naproxen for acute migraine in adults |
Naratriptan for acute migraine headaches in adults |
Narrow band imaging colonoscopy is not better than white light colonoscopy in detecting the patients with colorectal polyps. |
Narrow-band ultraviolet B phototherapy versus broad-band ultraviolet B or psoralen ultraviolet A photochemotherapy for treating psoriasis |
Nasal continuous positive airway pressure (nCPAP) for term neonates with respiratory distress |
Nasal continuous positive airway pressure for sleep-disordered breathing after stroke |
Nasal continuous positive airway pressure for sleep-disordered breathing after stroke |
Nasal continuous positive airway pressure levels for the prevention of morbidity and mortality in preterm infants |
Nasal continuous positive airways pressure immediately after extubation for preventing morbidity in preterm infants |
Nasal decongestants for the common cold |
Nasal decontamination (cleaning the nose with anti-bacterial products) for the prevention of surgical site infection in people carrying S aureus |
Nasal high flow therapy for breathing support in preterm babies |
Nasal intermittent positive pressure ventilation (NIPPV) versus nasal continuous positive airway pressure (NCPAP) for apnea of prematurity |
Nasal intermittent positive pressure ventilation (NIPPV) versus nasal continuous positive airway pressure (NCPAP) for preterm neonates after extubation |
Nasal intermittent positive pressure ventilation (NIPPV) versus nasal continuous positive airway pressure (NCPAP) for preterm neonates after extubation |
Nasal irrigation with saline (salt water) for the symptoms of chronic rhinosinusitis |
Nasal masks versus nasal prongs for continuous positive airway pressure in preterm infants |
Nasal packing for reducing morbidity following septal surgery |
Nasal saline for allergic rhinitis |
Nasal saline for allergic rhinitis |
Nasal saline irrigation for acute upper airway infection symptoms |
Nasal versus oral intubation for mechanical ventilation of newborn infants |
Nasal versus oral route for placing feeding tubes in preterm or low birth weight infants |
Nasogastric decompression used routinely after abdominal surgery does not speed recovery. |
Nasogastric tubes versus nasojejunal tube for feeding people with severe acute pancreatitis |
Natalizumab for multiple sclerosis |
Natalizumab for treatment of active Crohn's disease |
National Eye Institute Awards $5 Million for Cochrane Eyes and Vision US Project |
National government initiatives to reduce salt intake in populations |
National one-click access to evidence-based Cochrane Reviews for South Africans |
Natriuretic peptide-guided treatment for preventing death and cardiovascular events among patients with risk factors for heart disease |
Natriuretic peptides for acute heart failure |
Natural cycle in vitro fertilisation for subfertile couples |
Near-infrared spectroscopy for fetal assessment during labour |
Nebulised adrenergic agonists for acute croup |
Nebulised deoxyribonuclease for viral bronchiolitis in children younger than 24 months |
Nebulised morphine for severe interstitial lung disease |
Nebulised surfactant in preterm infants with or at risk of respiratory distress syndrome |
Nebulisers for giving medication for cystic fibrosis |
Nebulized epinephrine for croup in children |
Nebulized racemic epinephrine for extubation of newborn infants |
Nedocromil sodium for chronic asthma in children |
Nedocromil sodium for preventing exercise-induced bronchoconstriction |
Nedocromil sodium versus sodium cromoglycate for preventing exercise-induced bronchoconstriction |
Need for further randomised clinical trials to assess the role of cholecystectomy in patients with suspected gallbladder dyskinesia |
Needle aspiration compared to incision and drainage for the treatment of peritonsillar abscess (quinsy) |
Needle characteristics that reduce the occurrence of post-dural puncture headache (PDPH) |
Needle size for vaccination procedures in children and adolescents |
Needle suspension surgery for urinary incontinence in women |
Needling for encapsulated trabeculectomy filtering blebs |
Negative pressure wound therapy (NPWT) for treating partial-thickness burns |
Negative pressure wound therapy for managing the open abdomen after midline laparotomy |
Negative pressure wound therapy for open traumatic wounds |
Negative pressure wound therapy for treating foot wounds in people with diabetes mellitus |
Negative pressure wound therapy for treating leg ulcers |
Negative pressure wound therapy for treating pressure ulcers |
Negative pressure wound therapy for treating surgical wounds healing by secondary intention (open surgical wounds) |
Neo-adjuvant and adjuvant hormone therapy for localised and locally advanced prostate cancer |
Neoadjuvant chemotherapy and surgery versus chemoradiotherapy for locally advanced cervical cancer |
Neoadjuvant chemotherapy for patients having resection or ablation of liver metastases from colorectal cancer. |
Neoadjuvant chemotherapy in locally advanced rectal cancer |
Neoadjuvant chemotherapy or chemoradiotherapy versus upfront surgery alone for resectable or borderline resectable pancreatic cancer |
Neoadjuvant chemotherapy versus none for resectable gastric cancer |
Neonatal vitamin A supplementation for prevention of mortality and morbidity among term neonates in low and middle income countries |
Neostigmine for reversing muscle paralysis in children following surgery |
Neostigmine for the treatment of acute colonic pseudo-obstruction |
Nerve blocks for initial pain management of thigh bone fractures in children |
Nerve growth factor for neuropathic pain |
Nerve-sparing radical hysterectomy for early stage cervical cancer |
Neurally adjusted ventilatory assist for neonatal respiratory support |
Neuraminidase inhibitors for preventing and treating influenza in children |
Neuraxial anaesthesia for surgical correction of arterial vascular obstruction in the lower limbs |
Neuroaid for improving recovery after ischemic stroke |
Neurodevelopmental treatment approaches for children with cerebral palsy |
Neurokinin-1 receptor antagonists for prevention of chemotherapy-related nausea and vomiting in adults |
Neuromodulation (desynchronisation) for tinnitus in adults |
Neuromodulators for pain management in rheumatoid arthritis |
Neuromuscular blocking agents for acute respiratory distress syndrome |
Neuromuscular blocking agents for patients with acute respiratory distress syndrome |
Neuromuscular electrical stimulation for the prevention of venous thromboembolism |
Neuromuscular paralysis for newborn infants receiving mechanical ventilation |
Neurophysiological model-based treatments for tinnitus |
Neuroprotection (medicines to protect nerves involved in sight) for treatment of glaucoma in adults |
Neuroprotective effect of sulfonylurea drugs for people with ischemic stroke |
Neuropsychological and psychological treatments for adults with newly diagnosed epilepsy |
Neuropsychological tests for the diagnosis of Alzheimer’s disease dementia and other dementias: a generic protocol for cross-sectional and delayed-verification studies |
Neuroreflexotherapy for non-specific low-back pain |
Neurosurgery for obsessive-compulsive disorder, other anxiety disorders and depressive disorders |
Neurosurgical interventions for the treatment of classical trigeminal neuralgia |
New (test) |
New appointments to Cochrane’s Governing Board |
New Campbell review confirms little or no effect of community deworming |
New Cochrane Handbook for Systematic Reviews of Interventions |
New Cochrane health evidence challenges belief that omega 3 supplements reduce risk of heart disease, stroke or death |
New Cochrane Library Special Collection: Indigenous Health |
New Cochrane Review assesses different HPV vaccines and vaccine schedules in adolescent girls and boys |
New Cochrane review assesses how accurate antibody tests are for detecting COVID-19 |
New Cochrane review assesses the benefits and harms of exercise for preventing falls in older people living in the community |
New Cochrane Review evidence suggests that nutritional labelling on menus in restaurants and cafes may reduce our calorie intake |
New Cochrane Review finds Alcoholics Anonymous and 12-Step Facilitation programs help people to recover from alcohol problems |
New Cochrane Review of chondroitin for relieving pain in osteoarthritis |
New Cochrane review on family-centred interventions for Indigenous early childhood well-being by primary healthcare services |
New Cochrane-wide peer review policy |
New collaborative website launched by UoM Cochrane Review Groups |
New evidence finds standardized cigarette packaging may reduce the number of people who smoke. |
New evidence helps health workers in the fight against Ebola |
New evidence shows how technology is actively supporting patients in managing their own health |
New generation antipsychotics for first episode schizophrenia |
New health evidence gives women informed choice in the prolapse surgery debate |
New health evidence gives women informed choice in the stress urinary incontinence surgery debate |
New independent study finds Cochrane’s transparency over reporting financial conflicts of interest is leading the way |
New learning opportunities in evidence-based health care for medical students in Sweden |
New monitoring strategies for clinical trials |
New national licence agreement offers Switzerland full access to Cochrane evidence |
New National License Agreement Provides Brazil with Unlimited Access to the Cochrane Library |
New national license agreement provides India with unlimited access to the Cochrane Library |
New on the Cochrane Library: Best of 2016 Special Collection |
New on the Cochrane Library: Best of 2019 Special Collection |
New prognostic review: Predicting relapse or recurrence of depression |
New research finds omega-3 fatty acids reduce the risk of premature birth |
New research shows that exercise to improve skill and coordination can help reduce lower back pain |
New study finds that health literacy lessons help children make sense of health claims |
New treatments versus established treatments in randomized trials |
New types of anticoagulants to prevent deep vein thrombosis and pulmonary embolism following total hip or knee replacement surgery |
New WHO position statement on public disclosure of clinical trial data |
Newborn circumcision for the prevention of urinary tract infections in infancy |
Newborn resuscitation training programmes for improving the health and survival of newborns |
Newborn resuscitation with intact cord for non-vigorous term or late preterm infants |
Newborn screening for homocystinuria |
Newer alternative fat emulsions versus the conventional pure soybean oil based fat emulsions for intravenous nutrition in preterm infants. |
Newer anticonvulsants in the treatment of anxiety disorders |
Newer antidepressants for depression in children and adolescents |
Newer atypical antipsychotic medication versus clozapine for schizophrenia |
Newer generation antidepressants for depression in children and adolescents: a network meta-analysis |
Newer, third generation cephalosporins versus conventional antibiotics for treating acute bacterial meningitis |
News from Cochrane UK |
Next-generation sequencing for guiding matched targeted therapies in people with relapsed or metastatic cancer |
NHS Choices highlights new Cochrane evidence on yoga and asthma |
Niacin for people with or without established cardiovascular disease |
Nicergoline may improve cognition and behavioural function of people with mild to moderate dementia |
Nickel-titanium versus stainless steel instrumentation for orthograde endodontic therapy |
Nicotine for postoperative pain |
Nicotine for schizophrenia |
Nicotine receptor partial agonists for alcohol dependence |
Nidotherapy for schizophrenia |
Nifedipine for primary dysmenorrhoea (period pain) |
Nifuratel-Nystatin combination for the treatment of mixed infections of bacterial vaginosis, vulvovaginal candidiasis, and trichomonal vaginitis |
Nipple- and areola-sparing mastectomy for the treatment of breast cancer |
Nitazoxanide for chronic hepatitis C |
Nitrates (medicines) for achalasia (impaired swallowing) |
Nitrates for acute heart failure syndromes |
Nitrates for chronic heart failure |
Nitrates for reducing death and cardiac complications in participants during non-cardiac surgery |
Nitrates for stable angina |
Nitric oxide donors (nitrates), L-arginine, or nitric oxide synthase inhibitors for acute stroke |
Nitric oxide donors for cervical ripening and induction of labour |
Nitric oxide donors for the treatment of preterm labour |
Nitric oxide for preventing pre-eclampsia and its complications |
Nitric oxide for respiratory failure in infants born at or near term |
Nitroimidazole drugs are effective in the treatment of trichomoniasis in women. |
Nitrous oxide (laughing gas)-based techniques versus nitrous oxide-free techniques for general anaesthesia |
Nitrous oxide-based versus nitrous oxide-free general anaesthesia and accidental awareness during general anaesthesia in surgical patients |
Nivolumab for adults with Hodgkin's lymphoma |
No apparent differences in quality of life are found in rectal cancer patients with a permanent stoma when compared to non-stoma patients. |
No assured evidence on traditional Chinese medicine herbs (TCMHs) stopping bleeding from haemorrhoids but limited evidence on TCMHs alleviating some symptoms caused by haemorrhoids. |
No benefit from immunotherapy with Mycobacterium vaccae in people with tuberculosis |
No clear evidence that any pharmacological intervention is better than another in decreasing ischaemia reperfusion injury in liver resections |
No clear evidence that Cisapride relieves symptoms related to constipation or irritable bowel disease. |
No clear evidence to show any one optimal surgical technique is superior for treating pre-cancerous cervix abnormalities |
No consistent evidence of efficacy of galantamine in vascular cognitive impairment |
No convincing evidence either to support or refute the use of colchicine for patients with primary biliary cirrhosis |
No convincing evidence from one trial of the efficacy of cholinesterase inhibitors for delirium |
No convincing evidence from one trial of the efficacy of cholinesterase inhibitors for dementia with Lewy bodies |
No convincing evidence of a cognitive enhancing effect of Panax ginseng. |
No current evidence for an improvement in memory or other aspects of cognitive function of non-demented older people following DHEA supplements |
No current evidence to support the use of specialist epilepsy clinics |
No difference found in pregnancy rates for women using either the LNG-20 intrauterine system (IUS) or intra-uterine device (IUD) for contraception |
No evidence for an improvement in memory or other aspects of cognitive function following DHEA treatment in normal older people. |
No evidence for effectiveness of multidisciplinary team interventions for delirium in patients with chronic cognitive impairment |
No evidence for efficacy and safety of indomethacin for treatment of mild to moderate Alzheimer's disease |
No evidence for optimal management of patients with unresectable liver spread originating from intestinal hormone cells |
No evidence found from randomised trials for drugs to treat pregnant women with hyperthyroidism |
No evidence from randomised clinical trial for optimal management of resectable liver spread originating from intestinal hormone cells |
No evidence from randomised clinical trials for optimal management of patients with large bowel cancer spread to lymph glands draining the liver |
No evidence from randomised clinical trials for optimal treatment for gallbladder polyp |
No evidence from randomised controlled trials for or against the use of huperzine A in the treatment of people with mild cognitive impairment |
No evidence from randomised controlled trials for or against the use of Zhiling concoction in the treatment of people with vascular dementia |
No evidence from trials on the effects of non-surgical treatments for late radiation cystitis, and more research on drugs inserted into the bladder is worthwhile |
No evidence has been found of any significant general improvement in manifestations of agitation, other than aggression, among demented patients treated with haloperidol, compared with controls |
No evidence indicates that any of the measures used to protect patients' kidneys during the perioperative period are beneficial |
No evidence of benefit from vitamin B6 supplementation on mood or cognition of older people with normal vitamin B6 status or with vitamin B6 deficiency |
No evidence of benefit of Acetyl-l-carnitine for dementia |
No evidence of benefit of Ibuprofen for the treatment of Alzheimer's disease |
No evidence of benefit of partial liquid ventilation in adults with acute lung injury and some evidence of increased risk associated with its use |
No evidence of benefit of selegiline for Alzheimer's disease |
No evidence of efficacy of alpha lipoic acid for dementia |
No evidence of the efficacy and safety of D-cycloserine in the treatment of patients with Alzheimer's disease |
No evidence of the efficacy of nicotine for Alzheimer's disease |
No evidence of the efficacy of non-pharmacological interventions for domestic wandering in people with dementia due to lack of trials |
No evidence of the efficacy of snoezelen or multi-sensory stimulation programmes for people with dementia |
No evidence of the efficacy of vitamin B12 supplementation for cognitive function |
No evidence so far to support use of isotonic saline as a maintenance fluid instead of hypotonic saline |
No evidence supporting or refuting milk thistle for alcoholic and/or hepatitis B or C virus liver diseases |
No evidence that cannabinoids are effective in the improvement of disturbed behaviour in dementia or in the treatment of other symptoms of dementia |
No evidence that cooling patients undergoing brain surgery helps to either reduce death and severe disability or increase harm |
No evidence that folic acid with or without vitamin B12 improves cognitive function of unselected elderly people with or without dementia. Long-term supplementation may benefit cognitive function of healthy older people with high homocysteine levels |
No evidence that homeopathy is effective in treating dementia |
No evidence that insertion of drains after plastic and reconstructive surgery of the breast reduces complications |
No evidence that ischaemic preconditioning has a protective role in liver resections performed utilising vascular occlusion. |
No evidence that medical anti-shock trousers improve survival for people with trauma, and some suggestion they may worsen outcomes, but more trials are needed |
No evidence that oral antibiotic therapy is less effective for treating urinary tract infection than intravenous antibiotics |
No evidence that oximes are a useful treatment for organophosphate pesticide poisoning |
No evidence that subjective barriers prevent wandering of cognitively impaired people |
No evidence that treatment with gangliosides reduces death rate or improves life for survivors after spinal cord injury |
No evidence to assess surgical treatment in asymptomatic gallstones |
No evidence to evaluate the potential benefits and harms of cryotherapy in the treatment of hepatocellular carcinoma |
No evidence to show whether removing nail polish and finger rings prevents wound infection after surgery |
No evidence to suggest tamoxifen benefits patients with relapsed ovarian cancer |
No evidence to support anabolic-androgenic steroids for alcoholic liver disease |
No evidence to support or refute antioxidant supplements for patients with non-alcoholic fatty liver disease and/or steatohepatitis |
No evidence to support or refute drugs trying to influence insulin resistance in patients with non-alcoholic fatty liver disease and/or steatohepatitis |
No evidence to support or refute elective surgery for benign liver tumours |
No evidence to support or refute endoscopic retrograde cholangiopancreaticography (ERCP) with stenting in patients with malignant pancreaticobiliary diseases, awaiting surgery |
No evidence to support or refute glucocorticosteroids for patients with primary biliary cirrhosis |
No evidence to support or refute glucocorticosteroids for viral hepatitis C |
No evidence to support or refute probiotics for patients with non-alcoholic fatty liver disease and/or steatohepatitis |
No evidence to support or refute S-adenosyl-L-methionine for alcoholic liver diseases |
No evidence to support or refute the use of ischaemic preconditioning in liver transplantation |
No evidence to support the use of electrical stimulation in the management of rheumatoid arthritis |
No evidence to support the use of thioridazine for dementia |
No evidence to support use of adjuvant progestagens to prevent recurrence of endometrial cancer after surgery |
No evidence-based treatment option for inhalant dependence or abuse |
No major difference between the various surgical interventions for Anorectal fistula used as far as recurrence rates are concerned. |
No new evidence of the efficacy of validation therapy for people with dementia or cognitive impairment has been identified. The new study identified Schrijnemaekers 2002 was excluded because it was not deemed to be validation therapy. |
No randomised trials were found testing short-acting beta-2 agonists in people with bronchiectasis. |
No strong evidence about the effectiveness of Argon Plasma Coagulation therapy over other interventions for gastrointestinal bleeding. |
No strong evidence about the effects of sensory stimulation for a brain-injured person in a coma |
No strong evidence for any interventions for preventing infection in nephrotic syndrome |
No trials on effectiveness of treatments to prevent latent tuberculosis from developing into active disease in people exposed to multiple-drug-resistant tuberculosis (MDR-TB) |
Non pharmacological interventions for treatment of spasticity in Multiple Sclerosis (MS) |
Non surgical therapy for anal fissure. |
Non-acute percutaneous coronary intervention versus medical therapy in patients with ischaemic heart disease |
Non-antibiotic treatments for sore throat |
Non-antipsychotic catecholaminergic drugs for antipsychotic-induced tardive dyskinesia |
Non-aspirin, non-steroidal anti-inflammatory drugs for treating osteoarthritis of the knee |
Non-biologic pharmaceutical interventions for fatigue in rheumatoid arthritis |
Non-clinical interventions for reducing unnecessary caesarean section |