'As required' medication regimes for seriously mentally ill people in hospital
'Hospital at home' services to avoid admission to hospital
'Human' insulin versus animal insulin in people with diabetes mellitus
'Red-light cameras' cut casualty crashes at junctions with traffic lights
'Scared straight' and other juvenile awareness programs for preventing juvenile delinquency
'Third wave' cognitive and behavioural therapies versus other psychological therapies for depression
'Third wave' cognitive and behavioural therapies versus treatment as usual for depression
(1→3)β-D-glucan testing for the detection of invasive fungal infections in immunocompromised patients
(Oral antiviral treatment to prevent genital herpes outbreaks in immunocompetent and nonpregnant patients)
-ε4 allele for the diagnosis of Alzheimer's and other dementia disorders in people with mild cognitive impairment in a community setting
-ε4 allele for the diagnosis of Alzheimer's and other dementia disorders in people with mild cognitive impairment in a primary care setting
-ε4 allele for the diagnosis of Alzheimer's and other dementia disorders in people with mild cognitive impairment in a secondary care setting
11C-PIB-PET scan for early prediction of developing Alzheimer’s disease or other dementia in people with mild cognitive impairment (MCI)
21+7 day versus 24+4 day monophasic regimens of combined oral contraceptives for contraception
3,4-Diaminopyridine for myasthenia gravis
5-alpha-reductase inhibitors for lower urinary tract symptoms secondary to benign prostatic obstruction
5-ASA for management of symptomatic uncomplicated diverticular disease (SUDD)
5-ASA suppositories, enemas or foam for induction of remission in ulcerative colitis
5-Fluorouracil compared with placebo or no intervention during or after surgery for glaucoma
5-FU for genital warts in nonimmunocompromised individuals
A 'test and treat' strategy for elevated wound protease activity for healing in venous leg ulcers
A brief cogntive screening test (Mini-Cog) for the assessment of possible dementia
A coated, longer-lasting form of doxorubicin hydrochloride for the treatment of recurrent ovarian cancer
A Cochrane systematic review assessing topical antibiotics without steroids for treating chronically discharging ears with underlying eardrum perforations, in participants of any age
A Cochrane systematic review comparing systemic antibiotics and topical treatments for chronically discharging ears with underlying eardrum perforations, in participants of any age
A combination of chemotherapy and radiotherapy is more effective than radiotherapy alone for localised cancer of the esophagus (gullet).
A combination of graduated compression stockings and heparin seems to be the optimal prophylaxis for patients undergoing colorectal surgery.
A comparison of a local anaesthetic injection below the collarbone with other injection techniques for providing anaesthesia of the lower arm
A comparison of active cycle of breathing technique (ACBT) to other methods of airway clearance therapies in patients with cystic fibrosis
A comparison of botulinum toxin type A versus botulinum toxin type B for involuntary positioning of the head, or cervical dystonia.
A comparison of compression plates and locked nails for surgically fixing fractures of the upper arm bone (humerus) in adults
A comparison of endoscopic and surgical treatment of strictures in patients with Crohn’s disease
A comparison of multifocal and monofocal intraocular lens implants used in cataract surgery
A comparison of platinum-based and non-platinum-based chemotherapy regimens for the treatment of small cell lung cancer
A comparison of single and combined intravenous drug therapy for people with cystic fibrosis
A comparison of the effectiveness and safety of the two most common therapies for people with multiple sclerosis (MS)
A comparison of the effectiveness and safety of two different surgical treatments for heavy menstrual bleeding
A comparison of the efficacy of oral versus intravenous steroids in relapsing-remitting multiple sclerosis (RRMS)
A comparison of the healthy donor's experience of donating their blood stem cells to a patient who is to receive a stem cell transplant as treatment for cancer of their blood (e.g. leukaemia)
A comparison of two methods to join small and large bowel together in surgery
A comparison of usual chest physiotherapy to other methods of airway clearance in people with cystic fibrosis
A comparison of volume targeted ventilation modes with traditional pressure limited ventilation modes for newborn babies
A daily low dose of cotrimoxazole for preventing opportunistic infections in adults with HIV
A fixed daily dose of a low molecular weight heparin compared with an adjusted dose of unfractionated heparin for treating blood clots in the deep veins (venous thromboembolism)
A gentler form of mechanical breathing for people affected by severe lung failure
A long course (five days or more) of a low dose of corticosteroids may be considered as an adjunct therapy in patients with septic shock.
A meta-analysis of clinical trials comparing taxane containing chemotherapy with non-taxane containing chemotherapy for women following surgery for early breast cancer
A modified formulation of doxorubicin for the treatment of newly diagnosed ovarian cancer
A new, non-invasive diagnostic blood test - polymerase chain reaction - for people at risk of an invasive mould infection (aspergillosis)
A package of care to actively manage labour in women who are at low risk of complications to reduce caesarean section rates
A review of evidence on the use of interventions for people with autism spectrum disorder, based on the psychological model 'Theory of Mind'
A review of techniques for tubal sterilisation (blocking the fallopian tubes)
A review of the medical literature for evidence of whether the use of intravenous antibiotics, or devices impregnated with antibiotics, reduce the risks of infection during the surgical placement of catheters for the drainage of excess fluid from the brai
A review of the use of drugs that suppress the immune system (immunosuppressants) in myasthenia gravis.
A review of the ways in which healthcare professionals can be helped to involve their patients in the healthcare decision making process
A review of the ways that healthcare professionals can improve the use of suitable medicines for older people
A single beta lactam antibiotic versus a beta lactam-aminoglycoside combination for patients with severe infection
A single dose of ibuprofen administered orally to treat acute postoperative pain in adults
A single dose of primaquine added to malaria treatment to prevent malaria transmission
A spray containing ipratropium bromide administered into the nose to treat common cold symptoms
A structured collateral interview regarding cognition and function (the IQCODE) for assessment of possible dementia
A structured interview for assessing change in memory and other thinking skills (the IQCODE) for assessment of possible dementia
A systematic review and meta-analysis of randomised controlled trials of medication in treating anxiety disorders in children and adolescents
A tube fitted inside a vein to allow drug injections for people with cystic fibrosis
Ab interno trabecular bypass surgery with Trabectome for open angle glaucoma
Abacavir versus other nucleoside reverse transcriptase inhibitor (NRTI) backbone therapies for treatment of HIV infection
Abacavir-based triple nucleoside regimens for maintenance therapy in patients with HIV
Abatacept for rheumatoid arthritis
Abdominal decompression in normal pregnancy
Abdominal massage for the treatment of constipation
Abdominal surgical incisions for caesarean section
Abdominal wall lift for people undergoing gallbladder removal by a key-hole operation
Abortion after three months of pregnancy can be done by an operation or with medicines. This review looked at which way is better.
Absence of trials examining whether early removal of central venous catheters is beneficial or harmful in newborn infants with bloodstream infection.
Absorbable staples for uterine incision at caesarean section
Absorbable stitches for repair of episiotomy and tears at childbirth
Absorbable versus non-absorbable sutures for carpal tunnel release
Absorbent products for light urinary incontinence in women
Absorbent products for moderate-heavy urinary and/or faecal incontinence in women and men
Abstinence-only programs for preventing HIV infection in high-income countries (as defined by the World Bank)
Abstinence-plus programs for preventing HIV infection in high-income countries (as defined by the World Bank)
Academic support, career guidance, and social support might increase student enrollment and reduce drop-out rates among 'at-risk' health professional students
Acamprosate for alcohol dependent patients
Acanthopanax for acute ischaemic stroke
Acceptability, efficacy and safety of pharmacological interventions for cocaine dependence: an overview of Cochrane reviews
Acceptance and Commitment Therapy for schizophrenia and related disorders
Accommodative intraocular lenses compared with monofocal intraocular lenses in cataract surgery
Accuracy of assessment instruments for patients' competence to consent to medical treatment or research.
Accuracy of MRI, ultrasound and vaginal assessment for the diagnosis of levator ani muscle avulsion in women
ACE inhibitors for the treatment of high blood pressure
Acellular vaccines for preventing whooping cough (pertussis) in children
Acetaminophen (also called paracetamol) for the common cold in adults
Acetaminophen for osteoarthritis
Acetophenazine versus chlorpromazine for schizophrenia
Acetyl-L-carnitine for patients with hepatic encephalopathy
Acetyl-L-carnitine for the treatment of diabetic polyneuropathy
Acetylcholinesterase inhibitor treatment for myasthenia gravis
Acetylcholinesterase inhibitors versus antipsychotics for schizophrenia either alone or in combination with antipsychotics.
Acetylcysteine and carbocysteine to treat acute upper and lower respiratory tract infections in children without chronic broncho-pulmonary disease
Acetylcysteine for preventing contrast-induced nephropathy
Acid reflux treatment for globus pharyngeus
Action observation for upper limb rehabilitation after stroke
Action plans for chronic obstructive pulmonary disease
Action with problem drinkers can cut risk of injury
Active compression-decompression using a hand-held device for emergency heart massage
Active management of spontaneous labour versus routine care in women who have had one or more previous caesarean sections
Active management of third stage of labour with ergot alkaloid drugs (e.g. ergometrine)
Active versus expectant management in the third stage of labour
Active versus passive parental consent for improving participant recruitment and outcomes in studies targeting children
Active warming systems for preventing inadvertent perioperative hypothermia in adults
Activity restriction for short-term and medium-term outcomes following mild traumatic brain injury
Acupoint stimulation for postoperative ileus  following gastrointestinal surgery
Acupressure for motion sickness
Acupuncture and assisted conception
Acupuncture and dry-needling for low back pain
Acupuncture and related interventions for the symptoms of chronic kidney disease
Acupuncture and related interventions for the treatment of symptoms associated with carpal tunnel syndrome
Acupuncture and related interventions for treating plantar heel pain in adults
Acupuncture as a treatment modality for patients with glaucoma
Acupuncture for (sub)acute non-specific low-back pain
Acupuncture for acute hordeolum
Acupuncture for acute management and rehabilitation of traumatic brain injury
Acupuncture for acute stroke
Acupuncture for ADHD in children and adolescents
Acupuncture for adults with type 2 diabetes mellitus
Acupuncture for allergic rhinitis
Acupuncture for amblyopia in children
Acupuncture for angina pectoris
Acupuncture for Bell's palsy
Acupuncture for cancer-related pain in adults
Acupuncture for children with cerebral palsy
Acupuncture for chronic asthma
Acupuncture for chronic constipation
Acupuncture for chronic hepatitis B virus infection
Acupuncture for depression
Acupuncture for dysphagia in acute stroke
Acupuncture for elbow pain
Acupuncture for epilepsy
Acupuncture for female subfertility
Acupuncture for fibromyalgia
Acupuncture for Gilles de la Tourette's syndrome
Acupuncture for Guillain-Barré syndrome
Acupuncture for hypertension
Acupuncture for induction of labour
Acupuncture for insomnia
Acupuncture for irritable bowel syndrome
Acupuncture for menopausal hot flushes
Acupuncture for migraine prophylaxis
Acupuncture for multiple sclerosis
Acupuncture for mumps in children
Acupuncture for myofascial pain
Acupuncture for nausea and vomiting which has been induced by having chemotherapy treatment
Acupuncture for near-sightedness in children
Acupuncture for neck pain
Acupuncture for neuropathic pain in adults
Acupuncture for newborn babies with hypoxic ischemic encephalopathy (HIE)
Acupuncture for osteoarthritis
Acupuncture for overweight or obese people
Acupuncture for pain in endometriosis
Acupuncture for Parkinson's Disease
Acupuncture for people with autism spectrum disorders (ASD)
Acupuncture for period pain
Acupuncture for polycystic ovarian syndrome
Acupuncture for post-stroke upper limb pain
Acupuncture for postherpetic neuralgia
Acupuncture for premenstrual syndrome
Acupuncture for primary hypercholesterolaemia
Acupuncture for renal colic
Acupuncture for schizophrenia
Acupuncture for shoulder pain
Acupuncture for stress urinary incontinence in adults
Acupuncture for stroke rehabilitation
Acupuncture for sudden idiopathic sensorineural hearing loss
Acupuncture for sudden-onset ankle sprains in adults
Acupuncture for symptomatic gastroparesis
Acupuncture for symptomatic treatment of diabetic peripheral neuropathy
Acupuncture for tension-type headache
Acupuncture for the treatment of post-operative pain
Acupuncture for tinnitus
Acupuncture for treating functional dyspepsia
Acupuncture for treatment-related side effects in women with breast cancer
Acupuncture for turning a breech baby in pregnancy
Acupuncture for uterine fibroids
Acupuncture to treat vascular dementia
Acupunture and electroacupuncture for rheumatoid arthritis
Acupunture or acupressure for relieving pain in labour
Acute normovolaemic haemodilution versus preoperative autologous blood donation for patients undergoing major abdominal surgery
Acute tocolysis for uterine tachysystole or suspected fetal distress
Acyclovir can reduce the number of days with fever in otherwise healthy children with chickenpox, but its effect on sores and itching is not yet certain
Acyclovir for infectious mononucleosis (glandular fever)
Acyclovir for treating primary herpetic gingivostomatitis
AD-8 for diagnosis of dementia across a variety of healthcare settings
Adalimumab for rheumatoid arthritis
Adaptation of shift work schedules for preventing and treating sleepiness and sleep disturbances caused by shift work
Adding a second drug improved tumor response rate and survival rate in advanced non-small cell lung cancer (NSCLC). Adding a third drug had a weaker effect on tumor response and no effect on survival
Adding chemotherapy after surgery or radiotherapy in patients with invasive bladder cancer
Adding chemotherapy before surgery and/or radiotherapy in patients with invasive bladder cancer.
Adding plerixafor to G-CSF for stem cell mobilisation for autologous transplantation in people with certain cancers of the blood
Adding ribavirin to interferon increases the number of patients who clear hepatitis C virus but also leads to several adverse reactions
Adding the amino acid tyrosine to the diet of people with phenylketonuria
Addition of anti-leukotriene agents to inhaled corticosteroids for adults and adolescents with persistent asthma
Addition of d-cycloserine to cognitive and behavioural therapies for the treatment of anxiety and related disorders
Addition of drugs to a chemotherapy regimen for metastatic breast cancer
Addition of intravenous beta2-agonists to inhaled beta2-agonists for acute asthma
Addition of long-acting beta2-agonists to inhaled corticosteroids for chronic asthma in children
Additional bedtime medication for the control of night-time acid reflux from the stomach.
Additional chemotherapy with doxorubicin marginally improves tumour response but increases side effects with no improvement in survival
Additional exercise therapy for the recovery of function after stroke
Additional oxygen in the treatment of cystic fibrosis
Additional, non-surgical treatments for accelerating tooth movement in dental patients being treated with fixed braces
Adefovir dipivoxil for chronic hepatitis B
Adefovir dipivoxil for chronic hepatitis B
Adefovir dipivoxil versus other antiviral drugs for chronic hepatitis B
Adenoidectomy for recurrent of chronic nasal symptoms in children
Adenoidectomy for recurrent or chronic middle ear disease in children
Adenosine A2A receptor antagonist istradefylline for levodopa-induced complications in Parkinson's disease
Adenosine versus intravenous calcium channel antagonists for tachycardia in adults
Adenosine-diphosphate (ADP) receptor antagonists for the prevention of cardiovascular disease in patients with type 2 diabetes mellitus
Adenotonsillectomy for obstructive sleep apnoea in children
Adherence compounds in embryo transfer media for assisted reproductive technologies
Adhesive restorations for the treatment of dental non-carious cervical lesions
Adhesively or non-adhesively bonded amalgam restorations for dental caries
Adhesives for bonded molar tubes during fixed brace treatment
Adhesives for fixed orthodontic bands
Adhesives for fixed orthodontic brackets
Adjunctive antimicrobial photodynamic therapy for treating periodontal and peri-implant diseases
Adjunctive antioxidants for bipolar disorder
Adjunctive antithyroid drugs in radioiodine therapy for hyperthyroidism
Adjunctive corticosteroids for Pneumocystis jiroveci pneumonia in patients with HIV infection
Adjunctive medical expulsive therapy for kidney and ureteral stone fragments following shock wave lithotripsy
Adjunctive steroid therapy for managing pulmonary tuberculosis
Adjunctive therapies in addition to land-based exercise therapy for osteoarthritis of the hip or knee
Adjustable versus non-adjustable sutures for the eye muscles in strabismus surgery
Adjusted doses of oral misoprostol for treating slow progress in labour
Adjusted indirect comparison for estimating relative effects of competing healthcare interventions
Adjusting the pH of lidocaine solution for reducing pain on injection
Adjustment of antimicrobial agents for adults with sepsis, severe sepsis or septic shock
Adjuvant (supplementary treatment after initial treatment) platinum-based anti-cancer drugs for early stage cervical cancer
Adjuvant chemotherapy for small intestine adenocarcinoma
Adjuvant gonadotropin-releasing hormone analogues for chemotherapy induced premature ovarian failure in premenopausal women
Adjuvant radiotherapy for stage I endometrial cancer
Adjuvant therapy for completely resected stage II colon cancer
Adjuvant therapy for resected pancreatic adenocarcinoma
Adjuvant therapy for resected pancreatic cancer
Adjuvant treatment after hysterectomy for uterine leiomyosarcoma
Administering antimalarial drugs to prevent malaria in children during the malaria transmission season
Administration of antibiotic prophylaxis for elective inguinal hernia repair cannot be universally recommended.
Administration of antimalarial drugs to whole populations
Administration of prostaglandins to pregnant women before caesarean section to prevent breathing difficulties in newborn babies
Administration of uterotonic drugs before and after placental delivery as part of the management of the third stage of labour following vaginal birth