There is insufficient evidence to support the use of hyperbaric oxygen for treatment of patients with carbon monoxide poisoning |
There is limited evidence from three small trials suggesting that the correction of metabolic acidosis trials may have some beneficial effects on both protein and bone metabolism |
There is limited evidence to support the assumption that the care of people with dementia in special care units is superior to care in traditional nursing units. |
There is no compelling evidence to support the use of the herbal medicines identified in this review for treatment of HIV infection and AIDS. |
There is no convincing evidence that Ginkgo biloba is efficacious for dementia and cognitive impairment |
There is no evidence from randomised controlled trials for or against the use of 'Yizhi capsule' as a treatment for vascular dementia |
There is no evidence of a positive effect that estrogen replacement therapy can maintain cognitive function for a longer period of time (> five months) in women with Alzheimer's disease |
There is no evidence of difference in clinical and microbiological efficacy of quinolones for uncomplicated acute cystitis in women, but there is some evidence of differences in occurrence and range of adverse reactions. |
There is no evidence that adjunctive therapies for AIDS dementia are effective, though they are well-tolerated and safe. |
There is no evidence that aspirin improves the symptoms of vascular dementia |
There is no evidence that MPACs (PBT1 or PBT2) are of benefit in Alzheimer's dementia |
There is no evidence that radiotherapy could help to cure or to prolong the survival of patients with malignant pleural mesothelioma |
There is no evidence to indicate whether placement of a shunt to remove fluid is effective in the management of normal pressure hydrocephalus |
There is no evidence to recommend that patients with non-small cell lung cancer receive prophylactic radiotherapy to the brain following potentially curative treatment with surgery or radiotherapy |
There is no evidence to support azathioprine for patients with primary biliary cirrhosis |
There is no evidence to support routine drain use after liver resections |
There is no evidence to support the use of donepezil for patients with mild cognitive impairment (MCI). The putative benefits are minor, short lived and associated with significant side effects |
There is no strong evidence that any of the variations in surgical technique described in this review for placing implants have superior success rates |
There is not enough evidence about the safety and effectiveness of amantadine for people with dyskinesia in Parkinson's disease. |
There is not enough evidence about the safety and effectiveness of amantadine for people with Parkinson's disease. |
There is not enough evidence on whether pelvic floor exercises can prevent incontinence after childbirth or prostate surgery, but the evidence is most promising for women at high risk after childbirth. |
There is not enough evidence that anti-reflux therapies are effective in treating hoarseness |
There is not enough evidence to establish precise criteria for the prescription of prosthetic ankle-foot mechanisms in individuals with a lower limb amputation. |
There is not enough evidence to show that lowering body temperature can reduce nerve damage during coronary artery bypass surgery. |
There is not enough high quality evidence to show that dietary magnesium supplementation during pregnancy is beneficial |
There is some evidence that human growth hormone may help reduce growth problems in children with chronic kidney disease |
Thermotherapy (heat treatment) for treating osteoarthritis of the knee |
Thermotherapy (heat treatment) for treating rheumatoid arthritis |
Thiamine for prevention and treatment of Wernicke-Korsakoff syndrome in people who abuse alcohol |
Thiazide diuretics and hip fracture |
Thiazide diuretics for the treatment of high blood pressure |
Thiazides best first choice for hypertension |
Thiazolidinediones for dementia and mild cognitive impairment |
Thiazolidinediones for people with chronic kidney disease and diabetes |
Thienopyridine derivatives versus aspirin for preventing stroke and other serious vascular events in high vascular risk patients |
Thioridazine for schizophrenia |
Third-line systemic chemotherapy for small cell lung cancer |
Third-line systemic treatment for non-small cell lung cancer |
This review addresses two questions. First, "Does the oral administration of water soluble contrast media followed by serial abdominal radiographs during the following 24 hours predict the need for early operation or resolution?" |
This review aimed to assess how effective contraceptive implants were at preventing pregnancy and how acceptable women found them compared to other methods of contraception. |
This review assesses the usefulness surgery for anal fissure, a painful ulcer at the anal opening, by comparing the efficacy of various surgical procedures and how likely they are to result in complications. |
This review compares the safety and effectiveness of two of the most popular treatments for haemorrhoids, rubber band ligation (RBL) and excisional haemorrhoidectomy (EH). |
This review compares two injectable hormonal contraceptives containing only progestogen, namely depot medroxyprogesterone acetate (DMPA) and norethisterone oenanthate (NET-EN), for the risks and reasons of their discontinuation and for their clinical effe |
This review did not find strong evidence to demonstrate the effect of traditional Chinese herbal products in the treatment of stable angina |
This review examines strategies to enable the continued use of the antibiotic cotrimoxazole in patients with HIV/AIDS to treat or prevent opportunistic infections in patients who previously experienced hypersensitivity to this drug. |
This review examines the net impact of providing written action plans to children with asthma and their parents |
This review is no longer appropriate for update as liquid based cytology has superceded smear technology. |
This review is not appropriate for update since radiotherapy is now routinely combined with cisplatin and there have been no further studies using hydroxyurea. |
This review searched for trials of women followed up after their first treatment for cervical cancer to find out the best approach to this care. |
This systematic review focuses on long-term outcome of laparoscopic versus open surgery for colorectal cancer, including long-term complications and cancer outcome. |
This systematic review is on comparative effectiveness of different therapies used in short term management of gastro-oesophageal reflux disease (GORD) |
This week Catherine Spencer starts as Cochrane’s new Chief Executive Officer |
Thoracic endoscopic stent graft versus open surgery for thoracic aneurysm |
Thoracic epidural anaesthesia combined with general anaesthesia versus general anaesthesia alone for one-lung ventilation |
Three dimensional imaging (3D) compared with two dimensional (2D) imaging for key hole removal of gallbladder |
Three versus two treatments for H pylori infection |
Three-drug versus two-drug induction therapy regimens for patients with transplant-eligible multiple myeloma |
Thrombolysis for aneurysmal subarachnoid haemorrhage |
Thrombolysis for cerebral vein and dural sinus thrombosis |
Thrombolysis for treatment of acute deep vein thrombosis |
Thrombolytic agents for arterial and venous thromboses in neonates |
Thrombophilia testing for the prevention of recurrent venous thromboembolism |
Thrombopoietin mimetics for patients with myelodysplastic syndromes |
Thrombopoietin receptor agonists for prevention and treatment of chemotherapy-induced thrombocytopenia in patients with solid tumours |
Through the skin pinning for treating wrist fractures in adults |
Thumb-in-palm surgery appears to lead to modest improvement in hand function and quality of life in people with cerebral palsy. |
Thymic peptides for treatment of cancer patients in addition to chemotherapy or radiotherapy, or both |
Thymosin alpha1 for chronic hepatitis B |
Thymosin-ɑ1 for people with chronic hepatitis B |
Thyroid dysfunction during treatment with systemic antineoplastic therapy for childhood cancer |
Thyroid hormone replacement for subclinical hypothyroidism |
Thyroid hormone supplementation for the prevention of morbidity and mortality in infants undergoing cardiac surgery |
Thyroid hormone therapy or minimally invasive treatments for benign thyroid nodules |
Thyroid hormones for acute kidney injury |
Thyroid hormones for preventing neurodevelopmental impairment in preterm infants |
Thyroid surgery for Graves' disease and Graves' opthalmopathy |
Thyrotropin-releasing hormone added to corticosteroids for women at risk of preterm birth for preventing neonatal respiratory disease |
Thyroxine replacement therapy for subfertile women with autoimmune thyroid disease or mildly underactive thyroid |
Tiagabine add-on therapy for drug-resistant focal epilepsy |
Tiagabine in the maintenance treatment of bipolar disorder |
Tiagabine to treat acute affective episodes in bipolar disorder |
Tianma Gouteng Yin Formula for primary hypertension |
Ticlopidine plus aspirin is better than oral anticoagulants alone for reducing the risk of revascularization, non-fatal myocardial infarction and bleeding following stenting of coronary arteries |
Tidal versus other forms of peritoneal dialysis for patients with acute kidney injury |
Tight control of mild-to-moderate high blood pressure for pregnant women with pre-existing or gestational hypertension (without protein in the urine) to improve health outcomes |
Time course for blood pressure lowering of alpha blockers |
Time course for blood pressure lowering of angiotensin receptor blockers |
Time course for blood pressure lowering of angiotensin-converting-enzyme inhibitors |
Time course for blood pressure lowering of beta one selective blockers |
Time course for blood pressure lowering of dual alpha and beta blockers |
Time course for blood pressure lowering of thiazides |
Time magazine cites Cochrane evidence in a story on lowering blood pressure |
Time spent in rehabilitation and effect on measures of activity after stroke |
Time to publication for results of clinical trials |
Time-lapse systems for embryo incubation and embryo assessment for couples undergoing in vitro fertilisation and intracytoplasmic sperm injection |
Time-limited home-care reablement services (up to 12 weeks) for supporting older adults to live independently |
Timed intercourse for couples trying to conceive |
Timed intercourse for couples trying to conceive |
Timed voiding for the management of urinary incontinence in adults |
Timing of antiretroviral therapy initiation in HIV-positive people with cryptococcal meningitis |
Timing of initiation of kidney replacement therapy (dialysis) for acute kidney injury |
Timing of surgery for aneurysmal subarachnoid haemorrhage |
Timing of surgery for premenopausal women with breast cancer |
Timing of tracheostomy for critically ill patients who are predicted to be on long-term artificial respiration |
Timing of treatment for people with recent symptoms from neck artery narrowing |
Tinnitus Retraining Therapy (TRT) for tinnitus |
Tiopronin for chronic hepatitis B |
Tiotropium for managing COPD |
Tiotropium for stable chronic obstructive pulmonary disease |
Tiotropium versus ipratropium bromide in the management of COPD |
Tiotropium versus long-acting beta2-agonists (LABAs) in the management of COPD |
Tirilazad for acute ischaemic stroke |
Tirilazad for aneurysmal subarachnoid haemorrhage |
Tissue adhesives for closure of surgical skin incisions |
Tissue adhesives for traumatic lacerations in children and adults |
Tissue graft surgery to treat a wing-shaped growth (pterygium) in the eye |
Title to be added |
Title: Botulinum toxin type A and casting versus botulinum toxin type A or casting in treating toe-walking in children with cerebral palsy. |
Title: Chinese herbal medicines for menopausal symptoms |
TMC207 for treatment of people with pulmonary tuberculosis |
TNF-alpha inhibitors for juvenile idiopathic arthritis |
TNF-alpha inhibitors for juvenile idiopathic arthritis |
TNF-alpha inhibitors for psoriatic arthritis |
TNF-α blockers intervention compared to placebo or additional treatment for children with Kawasaki disease |
To assess the optimal of timing of administering antibiotics to sepsis patients in the emergency department |
To assess whether metered dose inhalers or nebulizers are better for delivering inhaled drugs to mechanically ventilated patients |
To continue taking or to stop taking antiplatelet drugs for a few days before non-cardiac surgery in adults |
To evaluate the effectiveness and safety of intermittent androgen suppression compared to continuous androgen suppression for treating prostatic cancer. |
To investigate if using ultrasound to look at anal muscles after childbirth reduces women's suffering from gas, liquid or solid stool leakage |
Tobacco packaging design for preventing tobacco uptake |
Tocilizumab for rheumatoid arthritis |
Tocilizumab for thyroid eye disease |
Tocolysis for preventing fetal distress in second stage of labour |
Tocolytics for preterm premature rupture of membranes |
Tocolytics for suspected intrapartum fetal distress |
Toe-brachial index and toe systolic blood pressure for the diagnosis of peripheral arterial disease |
Tofacitinib for rheumatoid arthritis |
Toileting assistance programmes for the management of urinary incontinence in adults |
Token economy for schizophrenia |
Tolerability of selective cyclooxygenase 2 (COX-2) inhibitors used for the treatment of rheumatological manifestations of inflammatory bowel disease |
Tong-xin-luo capsule for patients with coronary heart disease after percutaneous coronary intervention |
Tongue scraping for treating halitosis |
Tongxinluo (a traditional Chinese medicine) capsules may help patients suffering from unstable angina |
Tongxinluo capsule for acute stroke |
Tonsillectomy for PFAPA syndrome (a rare cause of recurrent fever, mouth ulcers, sore throat and swollen neck glands) |
Tonsillectomy versus tonsillotomy for obstructive sleep-disordered breathing in children |
Tonsillectomy with or without adenoidectomy versus no surgery for obstructive sleep-disordered breathing in children |
Tooth-colored resin fillings compared with amalgam fillings for permanent teeth at the back of the mouth |
Tooth-coloured, non-metallic fillings: is it better to repair or replace faulty non-metallic fillings for adults? |
Topical (applied to the skin) phenytoin for treating pressure ulcers |
Topical agents and dressings for fungating wounds (ulcers caused by cancer) |
Topical agents or dressings for reducing pain in venous leg ulcers |
Topical anaesthesia for nasogastric tube insertion |
Topical anaesthesia for needle-related pain in newborn infants |
Topical anaesthetic or vasoconstrictor (blood vessel narrowing) preparations for flexible fibre-optic nasal pharyngoscopy and laryngoscopy |
Topical analgesics for acute otitis media |
Topical anti-inflammatory agents for seborrhoeic dermatitis of the face or scalp |
Topical anti-inflammatory treatments for eczema: network meta-analysis |
Topical antibiotics (applied to the skin) for preventing surgical site infection in wounds that are stitched or held together another way |
Topical antibiotics for acne |
Topical antibiotics for people with chronic suppurative otitis media |
Topical antibiotics for treating bacterial keratitis: a network meta-analysis |
Topical antibiotics to help reduce death and respiratory infections in people in intensive care receiving mechanical ventilation |
Topical antihistamines and mast cell stabilisers for treating seasonal and perennial allergic conjunctivitis |
Topical antimicrobial agents (antibacterial products applied directly to wounds) for treating foot ulcers in people with diabetes |
Topical antiseptics compared with antibiotics for people with chronic suppurative otitis media |
Topical antiseptics for chronic suppurative otitis media |
Topical azelaic acid, salicylic acid, nicotinamide, sulphur, zinc, and fruit acid (alpha-hydroxy acid) for acne |
Topical benzoyl peroxide for acne |
Topical corticosteroids for nasal polyps |
Topical corticosteroids for treating phimosis in boys |
Topical emollient for preventing infection in preterm infants |
Topical emollient therapy for preventing infection in preterm infants in low- or middle-income countries |
Topical fluoride (toothpastes, mouthrinses, gels or varnishes) for preventing dental caries in children and adolescents |
Topical fluoride for treating dental caries |
Topical glyceryl trinitrate for lateral elbow pain |
Topical herbal interventions for gingivitis |
Topical herbal therapy for treating osteoarthritis |
Topical imiquimod cream for the treatment of cervical intraepithelial neoplasia |
Topical immunosuppressants for blepharitis in adults |
Topical interventions for recurrent aphthous stomatitis (mouth ulcers) |
Topical lidocaine (a local anaesthetic) for the treatment of postherpetic neuralgia (nerve pain) |
Topical lidocaine for neuropathic pain in adults |
Topical medicine instillation techniques for glaucoma |
Topical nasal corticosteroids versus oral antihistamines for allergic rhinitis |
Topical nasal steroids for intermittent and persistent allergic rhinitis in children |
Topical negative pressure therapy for treating chronic wounds |
Topical non-steroidal anti-inflammatory agents for diabetic cystoid macular oedema |
Topical non-steroidal anti-inflammatory drugs (NSAIDs) for the treatment of pain in traumatic corneal abrasions |
Topical non-steroidal anti-inflammatory drugs for acute musculoskeletal pain in adults |
Topical nonsteroidal anti-inflammatory drugs for chronic musculoskeletal pain in adults |
Topical oils for the prevention or treatment of dry skin in term infants |
Topical or systemic antifungal therapy for chronic rhinosinusitis |
Topical pimecrolimus for eczema |
Topical preparations for preventing stretch marks in pregnancy |
Topical retinoids for the treatment of acne vulgaris |
Topical rubefacients for acute and chronic musculoskeletal pain in adults |
Topical silver diamine fluoride for managing dental caries in children and adults |
Topical silver for treating infected wounds. |
Topical steroid for chronic rhinosinusitis without polyps |
Topical steroids for nasal airway obstruction in children with moderately to severely enlarged adenoids |
Topical steroids versus placebo for giant papillary conjunctivitis |
Topical tacrolimus for atopic dermatitis |
Topical treatment for blepharokeratoconjunctivitis (BKC) in children |
Topical treatment for facial burns |
Topical treatment for hemorrhoids |
Topical treatment for vaginal candidiasis (thrush) in pregnancy |
Topical treatment with a blood-clot promoting drug to reduce bleeding |
Topical treatment with cyclosporine A eyedrops for inflammation of the surface of the eye |
Topical treatments and photodynamic therapy for actinic keratosis of the face and scalp |
Topical treatments and skin-resurfacing techniques for skin ageing |
Topical treatments for athlete's foot |
Topical treatments for eczema: a network meta-analysis |
Topical treatments for genital lichen sclerosus |
Topical treatments for HIV-related oral ulcers |
Topical treatments for psoriasis of the scalp |
Topical treatments for skin warts |
Topical treatments for vernal keratoconjunctivitis |
Topical umbilical cord care at birth |
Topical, light-based, and complementary interventions for acne: an overview of systematic reviews |
Topically applied anaesthetics for treating perineal pain after childbirth |
Topiramate add-on for drug-resistant focal epilepsy |
Topiramate for acute affective episodes in bipolar disorder |
Topiramate for juvenile myoclonic epilepsy |
Topiramate for preventing migraine attacks in adults |
Topiramate for treating neuropathic pain or fibromyalgia |
Topiramate versus carbamazepine as single drug treatment for epilepsy |
Topiramate versus carbamazepine monotherapy for partial onset seizures or generalized onset tonic-clonic seizures with or without other generalized seizure types |
Topotecan for advanced non-small cell lung cancer in first and second-line settings |
Topotecan is an active second line chemotherapeutic drug, used to treat patients with relapsed ovarian carcinoma |
Toremifene versus tamoxifen for advanced breast cancer |
Toric intraocular lenses versus limbal relaxing incisions for astigmatism in cataract surgery |
Toronto Colloquium - Early registration open |
Total and partial knee arthroplasty versus non-surgical interventions of the knee for moderate to severe osteoarthritis |
Total disc replacement for chronic low-back pain |
Total gastrectomy with splenectomy versus total gastrectomy alone for gastric cancer |
Total hip arthroplasty for osteoarthritis |
Total hip replacement surgery versus conservative care for hip osteoarthritis and other non-traumatic diseases |
Total joint replacement surgery for knee osteoarthritis and other non-traumatic diseases: a network meta-analysis |
Total joint replacement surgery versus conservative care for knee osteoarthritis and other non-traumatic diseases |
Total or near-total thyroidectomy versus subtotal thyroidectomy for multinodular non-toxic goitre in adults |
Total pancreatectomy and islet autotransplantation for chronic pancreatitis |
Total portosystemic shunt versus shunts preserving portal venous hepatic perfusion for variceal haemorrhage |
Touch therapies (Healing Touch, Therapeutic Touch and Reiki) for the treatment of pain relief for adults |
TPO receptor agonists for treating chronic idiopathic thrombocytopenic purpura |
Tracheal gas insufflation for the prevention of morbidity and mortality in mechanically ventilated newborn infants |
Tracheal suction at birth in non-vigorous neonates born through meconium-stained amniotic fluid |
Tracheal suctioning without disconnection in intubated, ventilated neonates |
Traction for hip osteoarthritis |
Traction for low-back pain |