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Long-acting beta2-agonists for bronchiectasis

Long-acting bronchodilators are used in asthma, so may also benefit people with bronchiectasis. However, there is no good evidence for this at present.

Background

Symptoms of bronchiectasis include chronic productive cough, wheeze, breathlessness and recurrent infections of the lower respiratory tract. Long-acting bronchodilators are being used more frequently in the management of people with this condition.

Objectives

To determine the effectiveness of long-acting bronchodilators in the management of bronchiectasis that is not due to cystic fibrosis.

Search strategy

We searched the Cochrane Airways Group Specialised Register of bronchiectasis trials. The latest searches were carried out in August 2010.

Selection criteria

Randomised controlled trials, with or without masking.

Data collection and analysis

The results of searches were reviewed against pre-specified criteria.

Main results

We were unable to identify any randomised controlled trials investigating the effectiveness of long-acting bronchodilator therapy in the management of bronchiectasis. An update search in August 2010 did not identify any new studies.

Authors' conclusions

Further research is needed to establish if long-acting bronchodilators have a role in the management of people with bronchiectasis.

Citation
Sheikh A, Nolan D, Greenstone M. Long-acting beta2-agonists for bronchiectasis. Cochrane Database of Systematic Reviews 2001, Issue 4. Art. No.: CD002155. DOI: 10.1002/14651858.CD002155.

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