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Calorie-controlled diets for chronic asthma

It is thought that high calorie diets may contribute to the development of asthma. Theoretically, reducing the amount of calorie consumed as part of a diet may help to alleviate the symptoms of asthma. This review was limited by the small size of the studies and the obese population of asthma patients recruited to the study. No firm conclusions can be drawn regarding the effects of dietary manipulation, and more research is required.

研究背景

The prevalence of asthma has increased in recent years. Epidemiological studies suggest a correlation between the onset of asthma and dietary nonallergic factors especially high calorie diet. These can be regarded as other potentially important risk factors.

研究目的

To observe the effect of dietary calorie reduction on chronic asthma in adults or children.

检索策略

We searched the Cochrane Airways Group Specialised Register of trials using prespecified terms. We assessed bibliographies from included studies, and contacted authors of known studies for additional information about published and unpublished trials. Date of most recent search: May 2006

纳入排除标准

Randomised-controlled trials of dietary calorie reduction were included.

资料收集与分析

Three authors assessed each study independently. Disagreement was resolved by consensus. Quality assessment was performed independently.

主要结果

One trial of fair methodological quality with a total of 38 patients suffering from chronic asthma was included. There were significant increases in FEV1 and FVC in the active treatment group compared with control. No data pertaining serious adverse effects were reported from the interventions.

作者结论

There is currently a very small amount of evidence assessing the effects of dietary interventions intended as part of a wide-ranging weight-loss programme. Whilst we are unable to recommend these strategies as concomitant interventions with drug-based therapy for the specific management of asthma, dietary interventions such as weight-loss programmes may provide benefits in specific patients. However, the impact of a calorie-controlled diet on the signs and symptoms of asthma in the general asthmatic population is yet to be established.

引用文献
Cheng J, Pan T. Calorie controlled diet for chronic asthma. Cochrane Database of Systematic Reviews 2005, Issue 3. Art. No.: CD004674. DOI: 10.1002/14651858.CD004674.pub2.

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