Normal pressure hydrocephalus is a rare but potentially treatable cause of dementia. Since the condition was first described in 1965, it has conventionally been treated by placement of a shunt to remove cerebrospinal fluid (CSF) from the ventricles of the brain. No trial has yet compared the placement of a shunt versus no shunt in a randomized controlled manner. Nor have the long-term outcomes of treated and untreated normal pressure hydrocephalus been compared. There is, therefore, no evidence for the use of shunts in the management of normal pressure hydrocephalus.
阅读完整摘要
Since the condition was first described in 1965, the syndrome of normal pressure hydrocephalus (NPH) has conventionally been managed by placement of a cerebrospinal fluid (CSF) shunt.
研究目的
To determine the effectiveness of shunting procedures in promoting stability or improvement in the neurological symptoms and signs of NPH.
检索策略
The Specialized Register of the Cochrane Dementia and Cognitive Improvement Group (CDCIG), The Cochrane Library, MEDLINE, EMBASE, PsycINFO, CINAHL and LILACS were searched on 27 March 2008 using the terms: "Shunt*" AND "normal pressure hydrocephalus". The CDCIG Specialized Register contains records from all major health care databases (The Cochrane Library, MEDLINE, EMBASE, PsycINFO, CINAHL, LILACS) as well as from many trials databases and grey literature sources.
纳入排除标准
Studies included for analysis were those involving the placement of a CSF shunt for the treatment of NPH as part of a randomized controlled trial.
资料收集与分析
No data matching the selection criteria were found.
主要结果
No randomized controlled trials of shunt placement versus no shunt were found.
作者结论
There is no evidence to indicate whether placement of a shunt is effective in the management of NPH.
