Leukotriene receptor antagonists are a new class of drug which may have an anti-inflammatory action in some patients with asthma. In theory they may also be of benefit in bronchiectasis, but no randomised controlled trials have yet been reported so it is not possible to make a recommendation about their use in this condition.
阅读完整摘要
Leukotriene receptor antagonists are a new class of drug that were initially identified for use in asthma. As they have an effect on neutrophil mediated inflammation, they may be of benefit in bronchiectasis.
研究目的
To determine whether leukotriene receptor antagonists have any additive benefit over and above conventional treatment for bronchiectasis (usually consisting of antibiotics and postural drainage).
检索策略
The Cochrane Airways Group Specialised Regsiter of trials and CENTRAL were searched up to May 2011.
纳入排除标准
Only randomised, controlled trials were considered
资料收集与分析
The results of searches were analysed by both authors
主要结果
No randomised, controlled trials were identified. The latest search was in May 2011.
作者结论
Further research is required to establish any benefit from the use of leukotriene antagonists in bronchiectasis.
