Bronchiectasis is a chronic respiratory disease. People with the condition experience difficulty in clearing mucus from their lungs, leaving them prone to infections. Atrovent and other anticholinergic agents are bronchodilators which could help with opening up the airways in people with bronchiectasis. We looked for randomised studies addressing this question but we could not identify any evidence for or against the use of anticholinergic drugs in the treatment of bronchiectasis.
阅读完整摘要
Anticholinergic agents block bronchoconstriction mediated by the vagus nerve and may also dry up bronchial secretions. They are effective in obstructive airways disease and may be beneficial in bronchiectasis
研究目的
To determine the effect of anticholinergic therapy in acute exacerbations and stable bronchiectasis.
检索策略
The Cochrane Airways Group Specialised Register was searched and bibliographies of retrieved papers were checked. Searches are current as of May 2011.
纳入排除标准
Only randomised controlled trials were considered.
资料收集与分析
Two reviewers assessed the retrieved studies working independently.
主要结果
Twelve studies were identified, of which six were obtained for further scrutiny. One was translated from Italian. None met the inclusion criteria. An update search conducted in May 2011 did not yield any new studies.
作者结论
No formal recommendations can be made about the use of anticholinergic therapy in acute or stable bronchiectasis based on the literature currently available.
