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Hormones for suspected impaired fetal growth

No evidence to show whether the unborn baby's growth improves when pregnant women take extra oestrogen.

Babies in the womb growing more slowly than expected (impaired fetal growth) may be receiving too few nutrients from their mother's blood. Hormones are chemicals produced by glands in the body for growth, metabolism (how the body uses food) and reproduction. Oestrogen (the female hormone) is thought to increase blood flow from pregnant women to their babies, thus potentially providing more nutrients. The review of trials has found no evidence to show whether the baby's growth improves when pregnant women take extra oestrogen. There is no evidence from trials on the effects of oestrogen supplementation on women and their babies.

研究背景

It has been suggested that oestrogens may improve fetal growth due to an increase in nutritional supply to the fetus from greater uterine blood flow.

研究目的

The objective of this review was to assess the effects of hormone administration for suspected impaired fetal growth and perinatal outcome.

检索策略

We searched the Cochrane Pregnancy and Childbirth Group's Trials Register (June 2009).

纳入排除标准

Acceptably controlled trials of hormone administration for suspected impaired fetal growth which report fetal, perinatal or maternal outcomes.

资料收集与分析

Eligibility and trial quality were assessed.

主要结果

No studies were included since none of the potentially relevant trials reported clinical outcomes.

作者结论

There is not enough evidence to evaluate the clinical use of hormone administration for suspected impaired fetal growth.

引用文献
Say L, Gülmezoglu AM, Hofmeyr GJ. Hormones for suspected impaired fetal growth. Cochrane Database of Systematic Reviews 2003, Issue 1. Art. No.: CD000109. DOI: 10.1002/14651858.CD000109.

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