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Summarising synthesis findings using GRADE

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Cochrane Learning Live

GRADE tables – known as ‘summary of findings’ tables – provide a transparent, standardised and concise format for reporting findings from an evidence synthesis. They are complemented by GRADE informative statements which are used to communicate intervention effects and certainty of evidence in plain language. 

Session 8 of the GRADE Learning Live series concludes how GRADE is used in systematic reviews of interventions. 

Topics include:-

  • Content of a summary of findings tables
  • Deciding on the overall certainty of evidence 
  • Reporting reasons for ratings and other explanations
  • Communicating effect sizes and certainty through informative statements
  • GRADEpro software for preparing summary of findings tables

This webinar is suitable for those wanting to use GRADE to interpret and summarise findings in a systematic review. Some understanding of systematic review and GRADE methods for assessing certainty of evidence is assumed.


Presenter Bio

Miranda Langendam is an epidemiologist with a background in health sciences and a keen interest in evidence-based health care. After her PhD in infectious diseases epidemiology she worked as senior researcher at the Dutch National Health Care Institute and senior staff member of Cochrane Netherlands. Currently she is an assistant professor and principal investigator at the department of Public and Occupational Health of the Amsterdam University Medical Center (University of Amsterdam). The focus of her research and teaching is evidence synthesis methodology, in particular guideline development and implementation. Her research line covers a broad spectrum of projects: from developing core outcome sets and risk of bias instruments to evaluation of guideline implementation and development of methodological frameworks. As methodologist she contributed to numerous guidelines on a variety of topics, for example for WHO and the European Commission. She is a board member of the GRADE working group, co-chair of the Dutch GRADE network and an active member of Cochrane. 

Her mission is to improve quality of care by developing, evaluating and implementing guideline methods with the aim to establish high quality and impactful guidelines.

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