Screening tests for active pulmonary tuberculosis in children

To determine the sensitivity, specificity, and positive and negative predictive value of 1) the presence of one or more tuberculosis symptoms, or symptom combinations; 2) chest radiography; 3) Xpert MTB/RIF; 4) Xpert Ultra; and 5) combinations of the aforementioned tests as screening tests for detecting active pulmonary tuberculosis in children in the following groups.

This is a protocol.

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Health topics:

Child health > Diagnosis

Child health > Infectious disease > Tuberculosis

Child health > Lungs & airways > Respiratory infections: tuberculosis

Diagnosis > Diagnostic test accuracy

Infectious disease > Tuberculosis > Diagnosis

Lungs & airways > Respiratory infections > Tuberculosis

Published:

28 July 2020

Authors:

Vonasek B, Ness T, Takwoingi Y, Kay AW, van Wyk SS, Ouellette L, Marais BJ, Steingart KR, Mandalakas AM

Primary Review Group:

Infectious Diseases Group

See the full Review on

the Cochrane Library

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Citation
Vonasek B, Ness T, Takwoingi Y, Kay AW, van Wyk SS, Ouellette L, Marais BJ, Steingart KR, Mandalakas AM. Screening tests for active pulmonary tuberculosis in children (Protocol). Cochrane Database of Systematic Reviews 2020, Issue 7. Art. No.: CD013693. DOI: 10.1002/14651858.CD013693.

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