Statins for Smith-Lemli-Opitz syndrome

  1. To evaluate the efficacy of statin therapy in reducing the frequency or severity of the neurobehavioral abnormalities seen in people with SLOS (e.g. aggression, anxiety, irritability, self-mutilation, autistic behaviors, sleep disturbances, etc.) (Wassif 2017).
  2. To evaluate the potential effects of statin therapy on survival.

This is a protocol.