| Delivering the placenta in the third stage of labour |
| Delivery of intravenous anti-cancer therapy at home versus in hospital or community settings for adults with cancer |
| Delivery of nutrition (food) to critically ill adults other than by the person eating and swallowing the food/nutrition |
| Dementia Awareness Week |
| Dengzhanhua preparations for acute cerebral infarction |
| Denosumab for preventing fractures in postmenopausal women with osteoporosis |
| Denosumab for the treatment and prevention of postmenopausal osteoporosis |
| Dental cavity liners under tooth-colored resin fillings placed into permanent teeth in the back of the mouth |
| Dental extractions prior to radiotherapy to the jaws for reducing post-radiotherapy dental complications |
| Dental filling materials for managing carious lesions in the primary dentition |
| Dental fillings for the treatment of caries in the primary dentition |
| Dental hygiene in addition to drug treatment for Helicobacter pylori eradication |
| Dental imaging methods for the detection of early tooth decay |
| Dental treatments for preventing damage to the jawbones in people with cancer receiving radiotherapy to the head and neck |
| Depot bromperidol decanoate for schizophrenia |
| Depot flupenthixol decanoate for schizophrenia or other similar mental illnesses |
| Depot fluphenazine decanoate and enanthate for schizophrenia |
| Depot fluspirilene for schizophrenia |
| Depot haloperidol decanoate for schizophrenia |
| Depot perphenazine decanoate and enanthate for schizophrenia |
| Depot pipotiazine palmitate and undecylenate for schizophrenia |
| Deprescribing of chronic benzodiazepine receptor agonists for insomnia in adults |
| Depression rating scales for detection of major depression in people with dementia |
| Desferrioxamine mesylate (desferrioxamine) for managing excess iron levels in the blood of people with thalassaemia who depend on blood transfusions |
| Design-based methods to influence the completeness of response to self-administered questionnaires |
| Desipramine for neuropathic pain in adults |
| Desmopressin acetate (DDAVP) for preventing and treating acute bleeds during pregnancy in women with congenital bleeding disorders |
| Desmopressin acetate (DDAVP) for preventing and treating bleeding in people with mild or moderate haemophilia A |
| Desmopressin for bedwetting in children |
| Desmopressin for treating nocturia in men with lower urinary tract symptoms |
| Desmopressin use for reducing the need for blood transfusion for people having an operation |
| Despite their widespread use, the value of antibiotics in exacerbations of chronic obstructive pulmonary disease (COPD) remains controversial |
| Detecting recurrent colorectal cancer by testing for blood carcino-embryonic antigen (CEA). |
| Determining the optimal method of securely closing the base of the appendix during keyhole surgery after removal of the inflamed appendix |
| Detoxification treatments for opiate dependent adolescents |
| Development of type 2 diabetes mellitus in people with intermediate hyperglycaemia ('prediabetes') |
| Developmental care for promoting development and preventing morbidity in preterm infants |
| Device-modified trabeculectomy for glaucoma |
| Devices and pressure sources for administration of nasal continuous positive airway pressure (NCPAP) in preterm neonates |
| Devices that drain on to the surface of the eye beneath the surface layer to reduce eye pressure in people with or at risk of glaucoma |
| Devices to continuously monitor sugar (glucose) levels in the blood in newborns born preterm |
| Devices with safety features for preventing percutaneous exposure injuries in healthcare staff |
| Deworming school children in low- and middle-income countries |
| Dexamethasone and peripheral nerve block |
| Dexmedetomidine and clonidine for long-term sedation during mechanical ventilation in critically ill patients |
| Dexmedetomidine for prevention of acute pain after abdominal surgery in adults |
| Dexmedetomidine for procedural sedation in children |
| Dextropropoxyphene in a single dose taken on its own and also with paracetamol to treat postoperative pain |
| Diabetes as a risk factor for tuberculosis disease |
| Diabetes drugs for preventing stroke and other blood vessel disease in people who have had a previous stroke or transient ischaemic attack |
| Diabetes management in primary care, outpatient and community settings can be improved by interventions targeting health professionals, and organisational interventions that increase continuity of care |
| Diabetes self-management education and support delivered by mobile health (m-health) interventions for adults with type 2 diabetes mellitus |
| Diacerein for osteoarthritis |
| Diagnosis of SARS-CoV-2 infection and COVID-19: accuracy of signs and symptoms; molecular, antigen, and antibody tests; and routine laboratory markers |
| Diagnostic accuracy of different scans following a CT scan for assessing whether pancreatic and periampullary cancer is resectable |
| Diagnostic accuracy of total serum bile acids or individual bile acids for intrahepatic cholestasis of pregnancy in woman claiming pruritus |
| Diagnostic accuracy of ultrasound screening for fetal structural abnormalities during the first and second trimester of pregnancy in low-risk and unselected populations |
| Diagnostic instruments for autism spectrum disorder (ASD) |
| Diagnostic test accuracy of self-administered cognitive assessment questionnaires for dementia |
| Diagnostic tests for assessing rotator cuff tears in people with shoulder pain for whom surgery is being considered |
| Diagnostic tests for pregnancy-related deep vein thrombosis |
| Dialysate sodium levels for chronic haemodialysis |
| Dialysate temperature reduction for intradialytic hypotension for people with chronic kidney disease requiring haemodialysis |
| Dialyser reuse for people with end-stage kidney disease requiring haemodialysis |
| Dialysis versus conservative management for stage 5 chronic kidney disease in the elderly |
| DianaHealth portal to improve clinical appropriateness of recommendations |
| Diaphragm compared to diaphragm with spermicide for birth control |
| Diaphragm pacing systems for amyotrophic lateral sclerosis / motor neuron disease |
| Diaphragm-triggered non-invasive respiratory support for preventing respiratory failure in preterm infants |
| Diaries for recovery from critical illness |
| Diazepam for treating tetanus |
| Diazepam monotherapy for epilepsy |
| Diclofenac for pain relief in children |
| Diclofenac with or without an antiemetic for acute migraine headaches in adults |
| Diet and exercise interventions for preventing excessive weight gain during pregnancy |
| Diet changes for infant colic |
| Diet or exercise, or both, for weight reduction in women carrying excess weight after childbirth |
| Diet, physical activity and behavioural interventions for the treatment of overweight or obese adolescents aged 12 to 17 years |
| Diet, physical activity and behavioural interventions for the treatment of overweight or obese children from the age of 6 to 11 years |
| Diet, physical activity or both for prevention or delay of type 2 diabetes mellitus and its associated complications in people at increased risk |
| Diet, physical activity, and behavioural interventions for the treatment of overweight or obesity in preschool children up to the age of 6 years |
| Dietary advice by dietitians to lower blood cholesterol can be more effective than advice by doctors, but may not be more effective than self-help resources. |
| Dietary advice during pregnancy to prevent gestational diabetes |
| Dietary advice for people with schizophrenia |
| Dietary advice for reducing cardiovascular risk |
| Dietary advice for the prevention of type 2 diabetes mellitus in adults |
| Dietary advice for treatment of type 2 diabetes mellitus in adults |
| Dietary Approaches to Stop Hypertension (DASH) for the primary and secondary prevention of cardiovascular diseases |
| Dietary changes in the treatment of Ménière's disease or syndrome |
| Dietary exclusions for improving established atopic eczema in adults and children |
| Dietary fibre to prevent cardiovascular disease |
| Dietary flavonoid for preventing colorectal neoplasms |
| Dietary intake in people living beyond cancer |
| Dietary interventions for lowering cholesterol in dialysis patients |
| Dietary interventions for maintaining cognitive function in cognitively healthy people in late life |
| Dietary interventions for maintaining cognitive function in cognitively healthy people in mid life |
| Dietary interventions for managing glucose abnormalities in people with cystic fibrosis |
| Dietary interventions for multiple sclerosis-related outcomes |
| Dietary interventions for preventing complications in idiopathic hypercalciuria |
| Dietary interventions for prevention of dementia in people with mild cognitive impairment |
| Dietary interventions for recurrent abdominal pain in children |
| Dietary interventions for stomach ache with no identifiable cause in children |
| Dietary interventions for the management of chronic constipation in children |
| Dietary marine fatty acids (fish oil) for asthma in adults and children |
| Dietary modifications for managing familial hypercholesterolaemia |
| Dietary patterns for adults with chronic kidney disease |
| Dietary regulation for 'gestational diabetes' |
| Dietary supplements for chronic gout |
| Dietary supplements for established atopic eczema in adults and children |
| Dietary supplements for pain during menstruation |
| Dietary supplements for preventing postnatal depression |
| Dietary supplements for treating foot ulcers in people with diabetes |
| Dieting to lose weight may lower blood pressure in overweight people with hypertension, but effects are modest and so dieting may not be effective alone. |
| Diets for inducing and maintaining remission in inflammatory bowel disease (IBD) |
| Diets for primary prevention of gallbladder stones in adults |
| Differences in effectiveness and adverse effects between different types of progestogens combined with ethinyl oestradiol (combined contraceptive pill) |
| Different anthracycline derivates for reducing cardiotoxicity in cancer patients |
| Different antibiotic regimens for treating pregnant women with bacteria in their urine and without symptoms of urinary tract infection |
| Different antibiotics for community-acquired pneumonia in otherwise healthy children younger than 18 years of age in hospital and outpatient settings |
| Different antibiotics for group A streptococcal pharyngitis |
| Different combinations of inhaled steroids and long-acting beta-agonists for chronic asthma (fluticasone/salmeterol versus budesonide/formoterol) |
| Different communication strategies for disclosing a diagnosis of schizophrenia and related disorders |
| Different communication strategies for disclosing results of diagnostic prenatal testing |
| Different corticosteroid treatments before early birth for improving outcomes for babies |
| Different devices for airway management in obese patients during general anaesthesia |
| Different dosage schedules for reducing damage to the heart in people with cancer receiving anthracycline chemotherapy |
| Different doses and durations of oral steroids for asthma attacks |
| Different doses of platelet transfusion for preventing bleeding in people with low platelet counts due to treatment-induced bone marrow failure |
| Different dressings used to protect the central venous catheter site with the aim of reducing the chance of developing a catheter-related infection |
| Different fluid therapy strategies for sepsis and septic shock |
| Different follow-up strategies for women after breast cancer treatment |
| Different formats and timing of educational interventions for surgical patients |
| Different functional treatment strategies for acute lateral ankle ligament injuries in adults |
| Different gases for insufflation of the abdominal cavity during keyhole abdominal surgery |
| Different implants used to fix certain types of hip fractures |
| Different infusion durations for preventing platinum-induced hearing loss in children with cancer |
| Different insulin regimens for type 2 diabetes mellitus |
| Different localization techniques during surgery of non-palpable breast lumps |
| Different magnesium sulphate regimens given to mothers to prevent preterm labour |
| Different magnesium sulphate regimens given to women at risk of preterm birth to help protect the baby’s brain and improve long-term outcomes |
| Different methods and settings for glucose monitoring for women with gestational diabetes during pregnancy |
| Different methods of cystic duct occlusion in patients undergoing laparoscopic cholecystectomy |
| Different methods of external fixation for treating distal radial fractures in adults |
| Different methods of manipulation for reducing pulled elbow in young children |
| Different methods of providing automatic external defibrillators to out-of-hospital cardiac arrests to prevent sudden cardiac death |
| Different methods of treating fractures of the shaft of the thigh bone in children and adolescents |
| Different methods of ventilation (controlling pressure vs volume) for people with acute respiratory failure due to lung injury |
| Different rate-controlling agents for the management of atrial fibrillation with rapid ventricular rate in the emergency department: a network meta-analysis |
| Different regimens of intravenous sedatives or hypnotics for electroconvulsive therapy (ECT) in adult patients with depression |
| Different regimens of penicillin antibiotics given to women routinely for preventing infection after caesarean section |
| Different stent graft types to repair thoracic aortic aneurysms |
| Different stent grafts for repair of abdominal aortic aneurysms |
| Different strains of probiotics for preventing morbidity and mortality in preterm infants: a network meta-analysis |
| Different strategies for diagnosing gestational diabetes mellitus (GDM) to improve maternal and infant health |
| Different strategies for using topical corticosteroids for established eczema |
| Different surgical approaches to access the infrarenal abdominal aorta during an operation to repair an abdominal aortic aneurysm |
| Different surgical techniques for treating blockage of the tear duct |
| Different systemic corticosteroid regimens for the emergency management of acute asthma |
| Different techniques of blood glucose monitoring in women with gestational diabetes for improving maternal and infant health |
| Different timing and dosages of corticosteroids to prevent lung injury |
| Different treatments for an esotropia (eye turns inward) that occurs within the first six months of life |
| Different types of dietary advice for women with gestational diabetes mellitus |
| Different types of energy source surgical instruments used in key-hole bowel surgery |
| Different types of implants for reconstructive breast surgery after mastectomy |
| Different types of intermittent pneumatic compression devices for preventing venous thromboembolism after total hip replacement |
| Different types of intranasal steroids for chronic rhinosinusitis |
| Different types of percutaneous endovascular treatments for acute ischemic stroke |
| Different types of powered toothbrushes for plaque control and healthy gums |
| Different ways of giving antibiotics to clear Pseudomonas aeruginosa infection in people with cystic fibrosis |
| Different-sized incisions for cataract surgery in people with age-related cataract |
| Digital behavioural interventions for people with sickle cell disease |
| Digital devices for tuberculosis treatment adherence |
| Digital interventions for delivering exercise in people with Cystic Fibrosis |
| Digital interventions for people with chronic obstructive pulmonary disease (COPD) |
| Digital retinal imaging for diagnosing diabetic retinopathy |
| Digital serious games for emotional recognition in people with autism spectrum disorder |
| Digital technologies to help people with asthma take their medication as prescribed |
| Digital technology for early identification of chest infections in people with cystic fibrosis |
| Digital tracking, provider decision support systems, and targeted client communication via mobile devices to improve primary health care |
| Digitalis for treatment of heart failure in patients in sinus rhythm |
| Digoxin for preventing or treating neonatal respiratory distress syndrome |
| Dihydroartemisinin-piperaquine for treating uncomplicated malaria |
| Dihydrocodeine in a single dose in the treatment of acute postoperative pain |
| Dilute versus full-strength formula in exclusively formula-fed preterm or low birth weight infants |
| Dimebon for Alzheimer's disease |
| Dimethyl fumarate (BG-12) first line oral treatment for people with multiple sclerosis |
| Dipeptidyl peptidase 4 (DPP-4) inhibitors for people with chronic kidney disease and diabetes |
| Dipeptidyl peptidase-4 (DPP-4) inhibitors for type 2 diabetes mellitus |
| Dipeptidyl-peptidase (DPP)-4 inhibitors and glucagon-like peptide (GLP)-1 analogues for prevention or delay of type 2 diabetes mellitus |
| Diposable nappies for preventing nappy rash in babies and infants. |
| Dipyridamole for preventing stroke and other vascular events in patients with vascular disease |
| Dipyrone for the acute treatment of migraine attacks in children and adults |
| Dipyrone for the treatment of headaches |
| Direct (primary) repair for penetrating colon injuries |
| Direct comparison of two antipsychotics (chlorpromazine versus clotiapine) for treating schizophrenia |
| Direct electrical current to the brain for language difficulties after stroke |
| Direct electrical current to the brain to improve rehabilitation outcomes |
| Direct factor Xa inhibitors versus low molecular weight heparins or vitamin K antagonists for prevention of venous thromboembolism in elective primary hip or knee replacement or hip fracture repair |
| Direct injection of corticosteroids into the fetus compared with injection into the mother for improving fetal outcomes when the mother is at risk of preterm birth |
| Direct oral anticoagulants for prevention of stroke in atrial fibrillation patients with chronic kidney disease |
| Direct renin inhibitors for preventing the progression of diabetic kidney disease |
| Direct thrombin inhibitors and factor Xa inhibitors for acute coronary syndromes: a network meta-analysis |
| Direct thrombin inhibitors and factor Xa inhibitors for atrial fibrillation |
| Direct thrombin inhibitors compared with vitamin K antagonists in people with atrial fibrillation for preventing stroke |
| Direct versus indirect bonding for bracket placement in orthodontic patients |
| Direct versus indirect veneer restorations for intrinsic dental stains |
| Direct-acting antivirals for chronic hepatitis C |
| Directly observing people with TB take their drugs to help them complete their treatment |
| Director of Cochrane South Africa honoured |
| Discharge planning from hospital |
| Disclaimer |
| Disclosing to parents newborn carrier status identified by routine blood spot screening |
| Discontinuation of epidural analgesia late in labour for reducing the adverse delivery outcomes associated with epidural analgesia |
| Discontinuation of intravenous oxytocin used to stimulate uterine contractions in the active phase of induced labour |
| Discounts announced for Latin American Colloquium registrants |
| Discover Cochrane Engage: Your gateway to volunteering in health evidence work |
| Disease management interventions for improving self-management in lower-limb peripheral arterial disease |
| Disease management programmes for heart failure |
| Disease modifying immunosuppressant drugs for juvenile-onset systemic lupus erythematosus |
| Disease-modifying anti-rheumatic drugs (DMARDs) for Sjogren’s syndrome |
| Disease-modifying anti-rheumatic drugs for rheumatoid arthritis: a systematic review and network meta-analysis |
| Disease-modifying drugs for people with a first clinical attack suggestive of multiple sclerosis |
| Disease-modifying pharmacological treatments for amyotrophic lateral sclerosis/motor neuron disease: an overview of intervention reviews |
| Disease-modifying therapy for HIV-related distal symmetrical polyneuropathy (including antiretroviral toxic neuropathy) |
| Disposable surgical face masks for preventing surgical wound infection in clean surgery |
| Dissection versus diathermy for tonsillectomy |
| Distal aortic perfusion during thoracoabdominal aneurysm repair for prevention of paraplegia |
| Distraction techniques for schizophrenia |
| Disulfiram as a medication for the treatment of cocaine dependence |
| Disulfiram for alcohol use disorder |
| Diuretic therapy for newborn infants with posthemorrhagic ventricular dilatation |
| Diuretics acting on the distal renal tubule for preterm infants with (or developing) chronic lung disease |
| Diuretics effective in lowering blood pressure when given as a second drug |
| Diuretics for heart failure in adults |
| Diuretics for people with chronic kidney disease |
| Diuretics for preventing and treating acute kidney injury |
| Diuretics for preventing pre-eclampsia |
| Diuretics for respiratory distress syndrome in preterm infants |
| Diuretics for the treatment of Ménière's disease or syndrome |
| Diuretics for transient tachypnoea of the newborn (TTN) |
| Diverse strategies for preventing high altitude illness |
| DNA technology increases pregnancy rate for women on IVF |
| Do a group of drugs known as monoaminergic agonists help the brain recovery after a severe injury? |
| Do acetylcholinesterase inhibitors reduce the core impairments associated with autism spectrum disorder |
| Do activity monitors help adults with stroke become more physically active? |
| Do acupuncture and related therapies help smokers who are trying to quit |
| Do additional surgical techniques at the lower end of bypasses in the leg improve the chance of the bypass working and saving the leg from amputation? |
| Do antibiotics prevent surgical site infection after breast cancer surgery? |
| Do antifungal medicines for vaginal yeast infections (thrush) work better if taken by mouth (orally) or placed in the vagina (intravaginally)? |
| Do antioxidant vitamin and mineral supplements slow down the progression of age-related macular degeneration (AMD)? |
