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Oral corticosteroids for bronchiectasis (stable and acute exacerbations)

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Bronchiectasis is a chronic respiratory disease. People with the condition experience difficulty in clearing mucus from their lungs, leaving them prone to infections. Oral steroids have a place in the management of acute and severe asthma. In bronchiectasis, inhaled steroids have small benefits but there is no evidence for or against the use of oral steroids for this condition.

Latar Belakang

Inflammation plays a significant role in the pathophysiology of bronchiectasis. Two small studies have shown small benefits from inhaled corticosteroids and oral corticosteroids may be of benefit in bronchiectasis

Matlamat

To determine the efficacy of oral corticosteroids in acute and stable bronchiectasis

Kaedah Pencarian

The Cochrane Airways Group Specialised Register was searched and bibliographies of retrieved papers were checked. Searches are current as of May 2011.

Kriteria Pemilihan

Only randomised controlled trials were considered

Pengumpulan Data dan Analisis

No trials met the inclusion criteria for the review.

Keputusan Utama

No randomised controlled trials were identified

Kesimpulan Pengarang

There are no randomised trials upon which to base recommendations about the use of oral corticosteroids in acute or stable bronchiectasis.

Petikan
Lasserson TJ, Holt K, Milan SJ, Greenstone M. Oral corticosteroids for bronchiectasis (stable and acute exacerbations). Cochrane Database of Systematic Reviews 2001, Issue 4. Art. No.: CD002162. DOI: 10.1002/14651858.CD002162.

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