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Microwave therapy for cervical ectropionYang KH, Liu YL, Wu T, Roberts H, Li J, Tian JH, Ma B, Tan JY, Zhang P SummaryMicrowave therapy for cervical ectropionIn western countries, cervical ectropion or erosion is considered to be a normal physiological process not requiring intervention. However, in China, cervical ectropion is considered as one of the most common types of chronic cervicitis and is often treated. One of the topical treatments widely used is microwave tissue coagulation. The authors identified 92 potential randomised clinical trials (RCTs) that compared microwave to no treatment or other treatments from Chinese databases but only three studies were identified as RCTs. The other studies were either retrospective records, or had incorrectly allocated the participants. For some studies we failed to make contact with the original study authors or could not obtain the full text to check the randomization methods that had been used. The review protocol also required participants to be symptomatic with mucopurulent discharge or have contact bleeding before treatment. The authors of the review considered that they could not answer the question about the rationale use of microwave therapy as only three low quality RCTs were found. Although the trials showed improved appearance of the cervix with microwave treatment compared with control therapy, it was not possible to ascertain whether the women were symptomatic before treatment. Further high quality studies are needed.
This is a Cochrane review abstract and plain language summary, prepared and maintained by The Cochrane Collaboration, currently published in The Cochrane Database of Systematic Reviews 2010 Issue 1, Copyright © 2010 The Cochrane Collaboration. Published by John Wiley and Sons, Ltd.. The full text of the review is available in The Cochrane Library (ISSN 1464-780X).
This version first published online:
October 17. 2007 AbstractBackgroundCervical ectropion is considered as one of the most common types of chronic cervicitis in China. Topical treatments for cervical ectropion including microwave tissue coagulation, are widely used in many hospitals in China. Nowadays, the necessary intervention for inflammatory cervical ectopy is controversial. ObjectivesTo compare the efficacy and potential side effects of microwave tissue coagulation with other interventions or no intervention in the treatment of cervical ectropion. Search strategyWe searched the Cochrane Menstrual Disorders and Subfertility Group Trials Register, Cochrane Central Register of Controlled Trials (CENTRAL, The Cochrane Library 2006, Issue 1), MEDLINE (1966 to 2005), EMBASE (1974 to 2005); The Chinese Biomedical Database (CBM, 1978 to 2005), The Chinese Medical Current Contents (CMCC, 1994 to 2005), CAJ Full-text Database (1994 to 2005) and Chinese Scientific Journals Database (1989 to 2005). We also searched related literature on the Internet with search engines such as Google, searched the reference lists of articles and hand searched relevant Chinese journals. Selection criteriaOnly authentic randomised controlled trials (RCTs) were included. Data collection and analysisTwo authors independently interviewed the original authors of claimed RCTs published in China and then assessed the quality of the three included RCTs and extracted data. Main resultsNo studies were found that met the participant inclusion criteria of the protocol. Although three studies were identified as authentic RCTs from 92 potential RCTs, it was not possible to confirm that the participants were symptomatic prior to treatment. Of these three studies two trials compared microwave therapy with laser and one compared microwave therapy with interferon-alpha suppository therapy. Microwave therapy showed a better effect on cervical appearance over laser therapy in the women with grade II and III and also improved cervical appearance over interferon-alpha suppository therapy. There was no difference in grade I women. Microwave therapy showed less adverse bleeding than laser therapy during the treatment. However, the methodological quality of the three RCTs was generally low. No trial compared treatment to no intervention and most trials didn't assess relief of symptoms or quality of life and satisfaction, which are very important to women. Authors' conclusionsThere are no RCTs comparing microwave therapy with other treatments or no treatment in symptomatic women with cervical ectropion. Although microwave therapy improved the appearance of the cervix over both laser therapy and interferon-alpha suppository therapy it is not clear if there is any other benefit for women. |