To learn more about the pharmacology of cerivastatin by characterizing the dose-related effect and variability of the effect of cerivastatin on the surrogate marker: low-density lipoprotein (LDL cholesterol). The effects of statins on morbidity and mortality is not the objective of this systematic review.Secondary objectives:
To characterize the dose-related effect and variability of effect of cerivastatin on the surrogate markers: total cholesterol, high-density lipoprotein (HDL cholesterol), and triglycerides.
To quantify the effect of various doses of cerivastatin on withdrawals due to adverse effects.
This is a protocol.