Cerivastatin for lowering lipids

Primary objective:

To learn more about the pharmacology of cerivastatin by characterizing the dose-related effect and variability of the effect of cerivastatin on the surrogate marker: low-density lipoprotein (LDL cholesterol). The effects of statins on morbidity and mortality is not the objective of this systematic review.

Secondary objectives:

To characterize the dose-related effect and variability of effect of cerivastatin on the surrogate markers: total cholesterol, high-density lipoprotein (HDL cholesterol), and triglycerides.

To quantify the effect of various doses of cerivastatin on withdrawals due to adverse effects.

This is a protocol.

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