Early planned removal versus expectant management of peripherally inserted central catheters to prevent infection in newborn infants

To determine the effectiveness of early planned removal of PICCs (up to two weeks after insertion), compared to an expectant approach or a longer fixed duration, in preventing infection in newborn infants. We will undertake subgroup analyses by gestational age at birth (< 32 weeks versus ≥ 32 weeks) (see: Subgroup analysis and investigation of heterogeneity).

This is a protocol.

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