To determine if early (within the first 48 hours of life) oropharyngeal administration of mother’s own colostrum can reduce rates of NEC, late onset invasive infections, and/or mortality in preterm infants. We will also assess trials for evidence of harm and safety (e.g. aspiration pneumonia). We will compare the use of early OPC with no OPC use, placebo, late OPC use and nasogastric colostrum use.
This is a protocol.