To determine the diagnostic accuracy of rapid tests at point of care (POC) for detecting syphilis infection in pregnant women, as verified with the combination of both reactive non-treponemal and treponemal tests as the reference standard.
To assess the accuracy of rapid POC testing according to type (non-treponemal and treponemal), infection stage (active versus inactive) and setting (low/middle-income vs high-income countries). In addition, we will to determine the diagnostic accuracy of POC test by brand without realize a formal comparison.
This is a protocol.