Sentinel node biopsy for diagnosis of lymph node involvement in endometrial cancer

To assess the diagnostic accuracy of sentinel lymph node biopsy in the identification of pelvic lymph node involvement in women with apparent early stage endometrial cancer.

  • To compare the diagnostic accuracy of different detection methods (Tc-99m with or without methylene or patent blue dye versus near infrared fluorescence tracers, such as indicyanine green (ICG)) and injection sites (subserosal versus cervical versus combined subserosal and cervical).
  • To compare the accuracy of sentinel lymph node detection by lymph node basin studied, i.e. pelvic versus para-aortic region.

This is a protocol.