To compare the effectiveness of oral medication with placebo and other treatments for painful bladder syndrome (interstitial cystitis) in adults.

The hypotheses to be tested are as follows:

1. Oral treatment is better than placebo or no treatment.
2. One oral treatment is better than another oral treatment.
3. Oral treatment is better than other methods of delivering pharmacological treatment.
4. Oral treatment is better than other modes of treatment eg. dietary and lifestyle changes.
5. Oral treatment combined with any other form of treatment is better than the other treatment alone.