The AllTrials campaign calls for all past and present clinical trials to be registered and their results reported. Hundreds of thousands of clinical trials have been conducted from which no or limited data have been made available; data critical to enabling doctors and regulators to make informed decisions about which treatments to use and fund. This is a serious problem for evidence-based healthcare researchers, including Cochrane, because all the evidence about a treatment is needed to understand its risks and benefits. Without a complete picture of trial results available, information is lost; bad treatment decisions may be made; financial investment into ineffective treatments are approved by governments and regulators; opportunities for better and more effective treatment are missed; and trials are repeated unnecessarily, duplicating effort and wasting resources.
AllTrials founders were Ben Goldacre, author of Bad Science, along with the charity Sense About Science; the Centre for Evidence Based Medicine in Oxford; the James Lind Initiative; the BMJ; and Cochrane.