Cochrane

The issue: Low-grade gliomas (LGGs) are slow growing, less aggressive brain tumors. The most optimal surgical management is under debate. The aim of the review: There are two surgical management strategies (treatments) for a person with a suspected LGG. These are biopsy, the surgical sampling of a small amount of tumor tissue, or resection, where ...

Background Hodgkin lymphoma (HL) is a malignancy of the lymphatic system. It occurs in children and adults, but it is more common in the third decade of life. It is one of the most curable forms of cancer. There are four stages of HL, stages I and II are considered as early stage HL and stages III and IV as advanced stage. Using risk factors such ...

Review question We reviewed the evidence of the effectiveness and side effects of 131I-meta-iodobenzylguanidine (131I-MIBG) therapy in patients with newly diagnosed high-risk (HR) neuroblastoma (NBL). Background NBL is a rare solid cancer that develops from special nerves cells. Patients with newly diagnosed HR NBL have a poor outcome, despite intensive ...

Background There are different types of lung cancer. One type is called small-cell lung cancer. Small-cell lung cancer is considered limited-stage if it is still within the chest or extensive-stage if it has spread outside the chest. Currently, chemotherapy and radiation therapy is recommended for treatment of limited-stage small-cell lung cancer if ...

Review question We reviewed the evidence about the effect of high-dose chemotherapy (medicines to kill the cancer) followed by autologous hematopoietic stem cell transplantation compared to standard-dose chemotherapy on overall survival (time from cancer diagnosis, or treatment, to death from any cause) in people with nonrhabdomyosarcoma soft tissue ...

Background The pancreas is an organ in the abdomen that secretes pancreatic juice that aids digestion; and it contains cells that produce important hormones such as insulin. Partial removal of the pancreas (pancreatic resection) is performed to remove cancerous and non-cancerous growths in the pancreas. During this process, new connections (anastomoses) ...

Background Hepatocellular carcinoma (primary liver cancer) arises from the liver cells and is distinct from cancer arising from other parts of the body and spreading to the liver. The Barcelona Clinic Liver Cancer (BCLC) group staging classifies cancer based on patient's life expectancy. It is broadly based on the size of the cancer, number of cancers ...

Background For the treatment of subfertility (delay in becoming pregnant), several medications are used to stimulate ovulation - the process of maturation and release of eggs from the ovaries. These drugs may also affect the endometrium, which is the layer of tissue lining of the womb (uterus). However, conditions that cause subfertility are known ...

Background Hepatocellular carcinoma (primary liver cancer) arises from the liver cells and is distinct from secondary liver cancer, arising from other parts of the body and spreading to the liver. Hepatocellular carcinoma can be classified in many ways. One classification is by Barcelona Clinic Liver Cancer (BCLC) group stage which classifies the ...

Review question We reviewed the evidence for effects of online support groups for women with breast cancer on emotional distress, uncertainty, anxiety, depression and quality of life. Background Women with a diagnosis of breast cancer can be affected physically, psychologically and emotionally. They are uncertain about the future and may need information ...