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Cochrane EvidencePublished 29 Sep 2016
Psychosocial interventions for cocaine and amphetamines abusers
Review question We reviewed the evidence about the effect of psychosocial treatment, which encompasses a wide variety of strategies that aim to change behaviour and support adults who are affected by harmful use, abuse or dependence on cocaine or amphetamines, including MDMA (ecstasy). Background Globally, cocaine and amphetamines are the two main ... -
Cochrane EvidencePublished 27 Sep 2016
Efficacy of psychostimulant drugs for cocaine dependence
Review question We investigated whether psychostimulant substitution was safe and effective for treating patients with cocaine dependence. Background Cocaine dependence is a frequent disorder for which no medication has been approved for treatment. Substitution therapy involves the replacement of the abused drug, which is often illegal and used ... -
Cochrane EvidencePublished 19 Mar 2016
Antipsychotic medications for cocaine dependence
Background Cocaine dependence is often associated with medical, psychological and social problems for individual and public health, generating problems for the community. Users play a role in the spread of infectious diseases such as AIDS, hepatitis and tuberculosis, as well as in crime, violence and neonatal drug exposure. Use of drugs such as antidepressants, ... -
Cochrane EvidencePublished 27 May 2015
Dopamine agonists for the treatment of people who misuse cocaine
Background A pharmacological agent with proven efficacy does not exist for treatment of cocaine misuse. Cocaine is an alkaloid derived from the erythroxylon coca leaf that is used as powder for intranasal or intravenous use or as crack, a free-base form which is smoked. Cocaine misuse is a major public health problem because its use can be associated ... -
Cochrane EvidencePublished 17 Apr 2015
Anticonvulsants for cocaine dependence
Background Cocaine is an illicit drug available as a powder for intranasal or intravenous use or smoked as crack. Short- and long-term use of this drug results in the spread of infectious diseases (for example, AIDS, hepatitis, tuberculosis), crime, violence and prenatal drug exposure. Cocaine dependence is associated with medical and psychosocial ... -
Cochrane EvidencePublished 7 Dec 2011
Antidepressants for cocaine abuse and dependence
A pharmacological agent with proven efficacy does not exist for treatment of cocaine dependence. Cocaine is an alkaloid derived from the erythroxylon coca leaf that is used as powder for intranasal or intravenous use or as crack, a free-base form which is smoked. Cocaine dependence is a major public health problem because its use can be associated with ... -
Cochrane EvidencePublished 20 Jan 2010
Disulfiram as a medication for the treatment of cocaine dependence
Cocaine is used as powder for intranasal or intravenous use, or smoked as crack. Dependence on cocaine can cause major public health problems because of its psychological, social and medical impacts, including the spread of infectious diseases such as AIDS, hepatitis and tuberculosis. No proven pharmacological treatment of cocaine dependency exists ... -
Cochrane EvidencePublished 25 Jan 2006
Auricular acupuncture for cocaine dependence
There are no effective drugs for the treatment of cocaine dependence, and doctors do not agree on a best method of treatment. More than 400 substance abuse clinics in the USA and Europe offer a treatment for cocaine dependence called auricular acupuncture. In this treatment, needles are usually inserted into five specific points in the ear, but some ...
