Cochrane

Background Cleft lip, also known as harelip, is one of the most common birth defects. The surgery to correct this defect can cause moderate to severe pain. Many of the drugs to reduce pain (analgesics) used in adults can have unwanted side effects in children. The treatment of the pain associated with the surgical correction of harelip can therefore ...

This updated review found there is limited evidence to support the use of pilocarpine hydrochloride in the treatment of radiation-induced salivary gland dysfunction ('dry mouth'). Salivary gland damage is a frequent and important complication of radiotherapy to the head and neck area; it causes dryness of the mouth with resultant problems with eating, ...

Review question This updated Cochrane systematic review aimed to look at evidence comparing use of sedation versus general anaesthesia to help children (up to 18 years of age) undergoing dental treatment. We wanted to see which (if any) approach allowed dental treatment to be carried out safely and effectively. We were also interested in the relative ...

Review question Do injections of local anaesthetic given whilst children and young people (aged 17 years or younger) are having dental treatment under general anaesthetic reduce the amount of pain felt afterwards? Background It can be difficult when giving dental treatment to children and young people to do it simply using a local anaesthetic (LA) ...