Cochrane

Bottom line No firm conclusions could be drawn about the effectiveness or harms of tramadol, alone or with paracetamol, in cancer pain. Background One person in two or three who gets cancer will suffer from pain that becomes moderate or severe in intensity. The pain tends to get worse as the cancer progresses. Tramadol hydrochloride is an opioid ...

Background Over 75% of people with cancer experience pain. Around 30% to 50% of these people have moderate to severe pain, which can have a negative impact on daily life. Cancer pain is a distressing symptom that tends to worsen as the disease progresses. Hydromorphone may help relieve these symptoms. Cancer-related pain is usually treated with medicines ...

People with cancer often experience pain. Cancer pain or cancer-related pain is one of the worst factors for these patients. This type of pain tends to get worse as the cancer progresses. Despite better analgesics (pain killers) and techniques, cancer pain is still a problem for many people. Traditionally, cancer pain was controlled by drugs. When these ...

Background This is an update of a previously published review published in 2012 investigating the efficacy of psychological therapies for parents of children with a longstanding or life-threatening physical illness. This review updates includes studies that have been conducted in the previous two years to give an up-to-date review of the evidence. Parenting ...

Background Surgery remains a mainstay of treatment for patients with many types of cancer. However, surgical stress and certain anaesthesia and pain medications commonly given during anaesthesia for cancer surgery are known to suppress body defences. Therefore, surgery and anaesthesia might contribute to long-term cancer recurrence. Different types ...

Fentanyl patches placed on the skin produced good pain relief for most people with moderate or severe cancer pain. One person in two or three who gets cancer will suffer from pain that becomes moderate or severe in intensity. The pain tends to get worse as the cancer progresses. Morphine taken by mouth has been used since the 1950s for controlling cancer ...

Chronic pain due to damaged nerves is called neuropathic pain and is common. Some people consider that certain types of neuropathic pain (reflex sympathetic dystrophy and causalgia, now known collectively as Complex Regional Pain Syndrome (CRPS)) are caused by the sympathetic nervous system. Sympathectomy is a destructive procedure that interrupts the ...

Abdominal pain is a major symptom in patients with inoperable pancreatic cancer and is often difficult to treat. Celiac plexus block (CPB) is a safe and effective method for reducing this pain. It involves the chemical destruction of the nerve fibres that convey pain from the abdomen to the brain. We searched for studies comparing CPB with standard ...

Irrespective of the initial screening test, colonoscopy is the final step in colorectal cancer screening. With the advent of the colorectal cancer screening programs in many countries, an increasing number of colonoscopies are being performed each year. Sedation for colonoscopy can improve patients' tolerance of the procedure and enhance colonoscopy ...