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Cochrane EvidencePublished 27 Jan 2015
Screening with urinary dipsticks for reducing morbidity and mortality
Urinary dipsticks are sometimes used for screening healthy people and patients that do not have symptoms of urinary disease. Urinary dipsticks can be used to test for several different substances, such as blood, sugar, protein, white blood cells and nitrite in the urine, which may indicate the presence of disease. Identified abnormalities sometimes ... -
Cochrane EvidencePublished 31 Aug 2014
Treatment of severe or progressive Kaposi's sarcoma in HIV-infected adults
Kaposi’s sarcoma was the first tumor to be described in association with HIV infection and is an AIDS-defining condition. It is also known as Kaposi's sarcoma-associated herpes virus (KSHV) as Herpes virus 8 (HHV8) is recognized as an essential and necessary factor in the pathogenesis of KS. Nonetheless, not all HHV-8-infected individuals will develop ... -
Cochrane EvidencePublished 9 Mar 2014
Antibiotics to prevent surgical site infection after breast cancer surgery
Breast cancer accounts for one in 10 of all new cancer cases diagnosed and surgical removal of the breast is a common treatment approach. An infection of the surgical wound is often a complication of surgery and taking antibiotics just before the operation significantly reduces the chances of developing an infection. The review is not able to establish ... -
Cochrane EvidencePublished 27 Jan 2014
Treatment of Kaposi sarcoma in children with HIV-1 infection
Using ART and chemotherapy together increases the likelihood of KS remission and reduces the risk of death in HIV-infected children diagnosed with KS. We found four observational studies that examined this question. Overall, we found that, though data are sparse and not adequately statistically adjusted, ART and chemotherapy together compared to chemotherapy ... -
Cochrane EvidencePublished 25 Nov 2013
Antibiotics for preventing early central venous catheter Gram positive infections in people with cancer
What is the problem? People with cancer who undergo anti-cancer treatment (chemotherapy) often have a tube inserted into a large vein (central venous catheter or CVC) through which their chemotherapy is given. As chemotherapy is usually administered at regular intervals over several months to years, long-term, semi-permanent, tunnelled CVCs (TCVCs) ... -
Cochrane EvidencePublished 29 Oct 2013
Influenza (flu) vaccination for preventing influenza in adults with cancer
Adults with cancer are prone to serious complications from influenza, more than healthy adults. The influenza vaccine protects against influenza and its complications. However, its effectiveness among cancer patients is unclear, as the immune dysfunction that accompanies cancer and as a result of chemotherapy might lower immune response to the vaccine. ... -
Cochrane EvidencePublished 1 Aug 2013
Influenza vaccination in children being treated with chemotherapy for cancer
Children with cancer are prone to developing infections. One of the viral infections is influenza (flu). This can run an innocent course in these children but some can develop severe complications. This review therefore focused on the efficacy of influenza vaccination in children with cancer. We identified no studies which assessed the clinical efficacy ... -
Cochrane EvidencePublished 25 Jun 2013
Catheter lock treatments for catheter-related infections in children with cancer
Oncology patients require frequent venous access for their cancer treatment. Therefore, more permanent catheters (central venous catheters (CVCs)) are often inserted. However, these can become infected and once the CVC becomes occupied by bacteria it is difficult to eradicate these micro-organisms. Lock solutions are medicines that are placed in the ... -
Cochrane EvidencePublished 16 Mar 2011
Varicella and influenza vaccines may reduce morbidity in patients with blood cancers
Viral infections cause significant disease and even death in patients with blood cancers. In the current systematic review of randomized controlled trials (RCTs) we aimed to evaluate the efficacy and safety of viral vaccines in these patients. The pre-defined primary outcome was incidence of the infection concerned. Secondary outcomes were mortality ...
