Cochrane

Venous thromboembolism (VTE) refers to blood clots in leg veins (known as deep venous thrombosis (DVT)), which can travel to the lungs (causing pulmonary embolism (PE)). PE can often be fatal. Signs of DVT include pain and swelling of the leg while signs of PE include breathlessness and chest pain. Risk factors for VTE include surgery, prolonged bed ...

Background Research evidence suggests that blood thinners may improve the survival of patients with cancer. This benefit could be related to a direct antitumor effect in addition to preventing blood clots. Study characteristics We searched the scientific literature for studies of anticoagulants in people with cancer. The evidence is current to February ...

Background Patients with cancer are at an increased risk of developing blood clots and might respond differently to blood thinners (anticoagulants) compared with patients without cancer. Study characteristics We searched scientific databases for clinical trials looking at the effects of long-term treatment with different blood thinners on blood ...

Background This review assessed the effects of oral anticoagulation (blood-thinning drugs) in people with cancer on survival, thromboembolic events, and bleeding outcomes. Study characteristics We searched the scientific literature for studies of anticoagulants in people with cancer. The evidence is current to February 2013. Key results We found ...

Background Patients with cancer undergoing surgical procedures are at an increased risk of blood clots. The blood thinner administered to prevent these clots can be either an unfractionated heparin (UFH) or low molecular weight heparin (LMWH). These two blood thinners may have different effectiveness and safety profiles. Study characteristics We ...

Background Patients with cancer are at an increased risk of blood clots. The blood thinner (anticoagulant) administered in the first few days can consist of unfractionated heparin (infused intravenously) or low molecular weight heparin (injected subcutaneously once or twice per day). These two blood thinners may have different effectiveness and safety ...

Children with cancer are at higher risk of thrombosis than children without cancer. This is a result of the disease itself but also of the cancer treatment and the presence of a central venous catheter. In this review, we investigated whether systemic treatments can prevent thrombosis. We identified six studies; two studies investigated low molecular ...

It is estimated that as many at 1.9 million deaths worldwide are attributable to physical inactivity, and that inactivity is a key risk factor in the development of most chronic diseases and cancers. This is alarming particularly because it is known that physical activity patterns track from childhood into adulthood. There is some evidence to suggest ...