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Cochrane EvidencePublished 28 Mar 2017
Treatment of very early- or early-stage primary liver cancer (hepatocellular carcinoma)
Background Hepatocellular carcinoma (primary liver cancer) arises from the liver cells and is distinct from cancer arising from other parts of the body and spreading to the liver. The Barcelona Clinic Liver Cancer (BCLC) group staging classifies cancer based on patient's life expectancy. It is broadly based on the size of the cancer, number of cancers ... -
Cochrane EvidencePublished 10 Mar 2017
Treatment of intermediate-stage primary liver cancer (hepatocellular carcinoma)
Background Hepatocellular carcinoma (primary liver cancer) arises from the liver cells and is distinct from secondary liver cancer, arising from other parts of the body and spreading to the liver. Hepatocellular carcinoma can be classified in many ways. One classification is by Barcelona Clinic Liver Cancer (BCLC) group stage which classifies the ... -
Cochrane EvidencePublished 7 Mar 2017
Radiotherapy administered externally for advanced hepatocellular carcinoma (primary liver cancer)
Review question What are the benefits and harms of radiotherapy administered externally in people with advanced liver cancer compared with other available therapies or no therapy? Background Hepatocellular carcinoma (primary liver cancer) is the most common cancerous tumour of the liver and the sixth most common cancerous tumour worldwide. In the ... -
Cochrane EvidencePublished 16 Feb 2016
Yttrium microsphere radioembolisation for advanced hepatocellular carcinoma (primary liver cancer)
Review question What are the benefits and harms of yttrium-90 microsphere radioembolisation in people with advanced liver cancer compared with other available therapies? Background Hepatocellular carcinoma (that is, primary liver cancer) is the most common malignant tumour of the liver and the fifth most common malignant tumour worldwide. In the ... -
Cochrane EvidencePublished 26 Jan 2015
Percutaneous ethanol injection for the treatment of early liver cancer
Background Liver cancer (hepatocellular carcinoma) is the fifth most common cancer worldwide. In the majority of people, liver cancer is diagnosed at advanced stages of the disease and is mostly accompanied by liver cirrhosis. In high-income countries, about 30% of people present with the more favourable early liver cancer. For these people, percutaneous ... -
Cochrane EvidencePublished 19 Dec 2013
Radiofrequency ablation for the treatment of liver cancer (hepatocellular carcinoma)
Background Liver cancer (hepatocellular carcinoma) is the fifth most common cancer worldwide. In the majority of patients, hepatocellular carcinoma is diagnosed at advanced stages of the disease and is mostly accompanied by liver cirrhosis. To date, there is no medical cure for patients with hepatocellular carcinoma, and treatment aims to slow tumour ... -
Cochrane EvidencePublished 13 Oct 2013
Microwave coagulation for liver metastases
Primary liver cancer and liver metastases from colorectal carcinoma are the two most common malignant tumours to affect the liver. The liver is second only to the lymph nodes as the most common site for metastatic disease. More than half of patients with metastatic liver disease will die from metastatic complications. Microwave coagulation involves ... -
Cochrane EvidencePublished 29 Jun 2013
Surgical resection versus liver transplantation for hepatocellular carcinoma
The two main treatments for hepatocellular carcinoma are liver transplantation and liver resection. To compare these two methods with each other, we searched literature databases until February 2013 for randomised clinical trials comparing hepatic resection versus liver transplantation as the methods of managing hepatocellular carcinoma. None of the ... -
Cochrane EvidencePublished 5 Jun 2013
Cryotherapy for liver metastases
Primary liver tumours and liver metastases from colorectal carcinoma are the two most common malignant tumours to affect the liver. The liver is second only to the lymph nodes as the most common site for metastatic disease. More than half of the patients with metastatic liver disease will die from metastatic complications. In cryoablation liquid nitrogen ... -
Cochrane EvidencePublished 31 May 2013
Percutaneous ethanol injection for liver metastases
Primary liver tumours and liver metastases from colorectal carcinoma are the two most common malignant tumours to affect the liver. The liver is second only to the lymph nodes as the most common site for metastatic disease. More than half of patients with metastatic liver disease will die from metastatic complications. In percutaneous ethanol injection, ...
