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Cochrane EvidencePublished 2 May 2017
Alvimopan for recovery of bowel function after radical cystectomy
Review question In patients who have their bladder removed, does the drug alvimopan compared to placebo help them recover their bowel function more quickly? Background Surgical removal of the bladder is a major operation that requires a stay of several days in hospital. One of the issues that keeps patients in hospital is not being able to eat normal ... -
Cochrane EvidencePublished 7 Mar 2017
Local treatment of non-muscle-invasive bladder cancer with Bacillus Calmette-Guérin with or without interferon-alpha
Review question We reviewed the evidence on the effects of local treatment of the bladder with Bacillus Calmette-Guérin (BCG) and interferon (IFN)-alpha (α) for cancer of the superficial layers of the bladder (known as non-muscle-invasive bladder cancer). Background Bladder cancer is a common cancer worldwide. Bladder cancer that is non-muscle invasive ... -
Cochrane EvidencePublished 27 Jan 2015
Screening with urinary dipsticks for reducing morbidity and mortality
Urinary dipsticks are sometimes used for screening healthy people and patients that do not have symptoms of urinary disease. Urinary dipsticks can be used to test for several different substances, such as blood, sugar, protein, white blood cells and nitrite in the urine, which may indicate the presence of disease. Identified abnormalities sometimes ... -
Cochrane EvidencePublished 18 Jan 2012
Intravesical gemcitabine for early stage bladder cancer
When bladder cancer is confined to the lining of the bladder it is treated surgically to remove the tumours. However, the tumours may recur and so another type of treatment is often used following surgery called intravesical therapy, whereby agents are instilled directly into the bladder to prevent tumour recurrence. These agents, such as Bacillus Calmette-Guérin ... -
Cochrane EvidencePublished 11 May 2011
Intravesical Bacillus Calmette-Guérin versus epirubicin for Ta and T1 bladder cancer
Transurethral resection (TUR) is the usual treatment method for patients who, when examined with a cystoscope, are found to have abnormal growths on the urothelium (stage Ta) and/or in the lamina propria (stage T1). However post-operation tumour recurrence is a major clinical problem. Intravesical Bacillus Calmette-Guérin or epirubicin following surgery ... -
Cochrane EvidencePublished 13 Apr 2011
Gemcitabine for unresectable, advanced or metastatic bladder cancer
When bladder cancer has spread beyond the bladder and is unresectable or metastatic, the possibility of cure is severely diminished. Treatment at this stage of the disease aims to reduce the disease-related symptoms and to improve quality of life. Chemotherapy is the main treatment offered to patients with this condition and one drug that has recently ... -
Cochrane EvidencePublished 20 Apr 2005
Adding chemotherapy before surgery and/or radiotherapy in patients with invasive bladder cancer.
The standard treatment for invasive bladder cancer is surgery (to remove the bladder and surrounding tissues), and/or radiotherapy (to kill the cancer cells). This review suggests that 50 out of 100 patients will be alive at five years, when they are given chemotherapy using a platinum drug in combination with other drugs, before having surgery and/or ... -
Cochrane EvidencePublished 23 Jul 2001
Major bladder surgery improves chances of survival for people with bladder cancer that has invaded the muscle, but more studies are needed
Bladder cancer is common worldwide. In rare cases, cancer spreads to the bladder muscle. A combination of surgery and radiation therapy (radiotherapy) is used to try to treat bladder cancer that has invaded the muscle. One treatment involves some radiotherapy, followed by major surgery to remove the bladder. Another treatment uses intensive radiotherapy, ... -
Cochrane EvidencePublished 23 Oct 2000
Local treatment with Bacillus Calmette-Guérin following surgery for superficial bladder cancer reduces the risk of the cancer returning.
Worldwide, bladder cancer is common in both men and women. In most cases, the cancer occurs in the superficial layers of the bladder and can be surgically removed. However, in many people the cancer returns. Drugs placed directly into the bladder tissue following surgery are therefore often used to try to prevent the cancer recurring. Bacillus Calmette-Guérin ...
