Cochrane

Protocol: To evaluate the effectiveness of antiretroviral resistance testing (genotypic or phenotypic) in reducing mortality and morbidity in people living with HIV.

Protocol: To assess the effects of ribavirin for treating people with Crimean Congo Haemorrhagic Fever (CCHF).

Review question What is the effect of zinc supplementation in the treatment of children with measles? Background Measles infection has reduced globally over the last decade, but large outbreaks still occur, especially in low-income countries. Zinc is one of the essential micronutrients necessary for the optimal functioning of the immune system. ...

Review question We reviewed the evidence about the effect of a non-typeable Haemophilus influenzae (NTHi) vaccine in preventing repeated H influenzae infections in people with chronic obstructive pulmonary disease (COPD) or chronic bronchitis. Background People with COPD can have frequent infections that worsen symptoms of their lung disease, that ...

Review question We wanted to know whether antibiotics improve outcomes for people with acute bronchitis. We also assessed potential adverse effects of antibiotic therapy. Background Acute bronchitis is a clinical diagnosis (based on medical signs and patient-reported symptoms) for an acute cough, which may or may not be associated with coughing ...

Protocol: Primary objective To evaluate the impact of space spraying on malaria transmission and vector populations, or the incremental impact when applied in combination with other malaria control methods, in comparison to equivalent conditions with no space spraying intervention. Secondary objective To guide future evaluations of strategies ...

Review question We wanted to know if people suspected to have inflammation of the membranes covering the brain and spinal cord (meningitis) due to infection with the meningococcal bacteria should be given antibiotics before the diagnosis is confirmed in order to prevent death or disability. We found one relevant study. Background Meningococcal disease ...

Protocol: To evaluate whether indoor residual spraying (IRS) in combination with long-lasting insecticide-treated nets (LLINs)/insecticide-treated nets (ITNs) causes an additional reduction to malaria transmission versus LLINs/ITNs alone.

Why did we do this review? HIV is still a major cause of death worldwide, particularly in Africa. HIV multiplies in the blood and damages the immune system. Therefore if HIV-positive, one is more vulnerable to contract infections. The current drug treatment, antiretroviral therapy (ART), stops the virus from multiplying thereby allowing the body's ...

Cochrane researchers assessed the accuracy of commercially-available rapid diagnostic tests and their prototypes (including TUBEX, Typhidot, Typhidot-M, Test-it Typhoid, and other tests) for detecting typhoid and paratyphoid (enteric) fever in people living in countries where the estimated number of individuals with the disease at any one time is greater ...